Cover ImageCover picture: Syncytia formed by the fusion of two cells expressing either CD4/CXCR4 or HIV-1 envelope glycoprotein complex undergo apoptosis. A critical step of the process leading to apoptosis is mitochondrial membrane permeabilization, leading to the dissipation of the mitochondrial transmembrane potential (top right), translocation of apoptosis-inducing factor from mitochondria to the nucleus (left), and mitochondriocystolic translocation of cytochrome c (bottom right). Nuclear apoptosis can be seen in the three panels as chromatin condensation. See related article in this issue by Ferri et al., pp. 1081-1092.
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Combined Stimulation with the T Helper Cell Type 2 Cytokines Interleukin (Il)-4 and IL-10 Induces Mouse Mast Cell Apoptosis
C. Fitzhugh Yeatman, II,Sarah M. Jacobs-Helber,Paria Mirmonsef,Sheila R. Gillespie,Lawrence Andrew Bouton,Henrietta A. Collins,Stephen T. Sawyer,Christopher P. Shelburne,John J. Ryan
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