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Journal Articles

Autoimmunity affecting the biliary tract fuels the immunosurveillance of cholangiocarcinoma

In Special Collection:

JEM Cancer Immunotherapy 2021

J Exp Med (2021) 218 (10): e20200853.

https://doi.org/10.1084/jem.20200853

Published: 08 September 2021

View article titled, Autoimmunity affecting the biliary tract fuels the immunosurveillance of cholangiocarcinoma

Includes: Supplementary data

Journal Articles

Ferroptosis in infection, inflammation, and immunity

In Special Collection:

Lipid Mediators in Immunity

Xin Chen, Rui Kang, Guido Kroemer, Daolin Tang

J Exp Med (2021) 218 (6): e20210518.

https://doi.org/10.1084/jem.20210518

Published: 12 May 2021

View article titled, Ferroptosis in infection, inflammation, and immunity

Journal Articles

Immune checkpoint inhibitors

Guido Kroemer, Laurence Zitvogel

J Exp Med (2021) 218 (3): e20201979.

https://doi.org/10.1084/jem.20201979

Published: 16 February 2021

View article titled, Immune checkpoint inhibitors

Journal Articles

Effects of interleukin-2 in immunostimulation and immunosuppression

In Special Collection:

Cytokines 2019

Jonathan G. Pol, Pamela Caudana, Juliette Paillet, Eliane Piaggio, Guido Kroemer

J Exp Med (2019) 217 (1): e20191247.

https://doi.org/10.1084/jem.20191247

Published: 14 October 2019

View article titled, Effects of interleukin-2 in immunostimulation and immunosuppression

Journal Articles

Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection

J Exp Med (2011) 208 (9): 1823–1834.

https://doi.org/10.1084/jem.20101805

Published: 22 August 2011

View article titled, Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection

Includes: Supplementary data

Journal Articles

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

J Exp Med (2011) 208 (4): 869.

https://doi.org/10.1084/jem.201002692084c

Published: 21 March 2011

View article titled, Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

Journal Articles

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

J Exp Med (2011) 208 (3): 491–503.

https://doi.org/10.1084/jem.20100269

Published: 07 March 2011

View article titled, Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

Includes: Supplementary data

Journal Articles

Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia

Changlian Zhu, Xiaoyang Wang, Johanna Deinum, Zhiheng Huang, Jianfeng Gao, Nazanine Modjtahedi, Martha R. Neagu, Michael Nilsson, Peter S. Eriksson, Henrik Hagberg, Jeremy Luban, Guido Kroemer, Klas Blomgren

J Exp Med (2007) 204 (8): 1741–1748.

https://doi.org/10.1084/jem.20070193

Published: 16 July 2007

View article titled, Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia

Journal Articles

Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

Noelia Casares, Marie O. Pequignot, Antoine Tesniere, François Ghiringhelli, Stéphan Roux, Nathalie Chaput, Elise Schmitt, Ahmed Hamai, Sandra Hervas-Stubbs, Michel Obeid, Frédéric Coutant, Didier Métivier, Evelyne Pichard, Pierre Aucouturier, Gérard Pierron, Carmen Garrido, Laurence Zitvogel, Guido Kroemer

J Exp Med (2005) 202 (12): 1691–1701.

https://doi.org/10.1084/jem.20050915

Published: 19 December 2005

View article titled, Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

Includes: Supplementary data

Journal Articles

Tumor cells convert immature myeloid dendritic cells into TGF-β–secreting cells inducing CD4⁺CD25⁺ regulatory T cell proliferation

François Ghiringhelli, Pierre E. Puig, Stephan Roux, Arnaud Parcellier, Elise Schmitt, Eric Solary, Guido Kroemer, François Martin, Bruno Chauffert, Laurence Zitvogel

J Exp Med (2005) 202 (7): 919–929.

https://doi.org/10.1084/jem.20050463

Published: 26 September 2005

View article titled, Tumor cells convert immature myeloid dendritic cells into TGF-β–secreting cells inducing CD4<sup> + </sup>CD25<sup> + </sup> regulatory T cell proliferation

Includes: Supplementary data

Journal Articles

Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope

Jean-Luc Perfettini, Maria Castedo, Roberta Nardacci, Fabiola Ciccosanti, Patricia Boya, Thomas Roumier, Nathanael Larochette, Mauro Piacentini, Guido Kroemer

J Exp Med (2005) 201 (2): 279–289.

https://doi.org/10.1084/jem.20041502

Published: 10 January 2005

View article titled, Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope

Journal Articles

NF-κB and p53 Are the Dominant Apoptosis-inducing Transcription Factors Elicited by the HIV-1 Envelope

Jean-Luc Perfettini, Thomas Roumier, Maria Castedo, Nathanael Larochette, Patricia Boya, Brigitte Raynal, Vladimir Lazar, Fabiola Ciccosanti, Roberta Nardacci, Josef Penninger, Mauro Piacentini, Guido Kroemer

J Exp Med (2004) 199 (5): 629–640.

https://doi.org/10.1084/jem.20031216

Published: 01 March 2004

View article titled, NF-κB and p53 Are the Dominant Apoptosis-inducing Transcription Factors Elicited by the HIV-1 Envelope

Includes: Supplementary data

Journal Articles

Lysosomal Membrane Permeabilization Induces Cell Death in a Mitochondrion-dependent Fashion

Patricia Boya, Karine Andreau, Delphine Poncet, Naoufal Zamzami, Jean-Luc Perfettini, Didier Metivier, David M. Ojcius, Marja Jäättelä, Guido Kroemer

J Exp Med (2003) 197 (10): 1323–1334.

https://doi.org/10.1084/jem.20021952

Published: 19 May 2003

View article titled, Lysosomal Membrane Permeabilization Induces Cell Death in a Mitochondrion-dependent Fashion

Journal Articles

Mitochondrial Apoptosis and the Peripheral Benzodiazepine Receptor : A Novel Target for Viral and Pharmacological Manipulation

Maria Castedo, Jean-Luc Perfettini, Guido Kroemer

J Exp Med (2002) 196 (9): 1121–1126.

https://doi.org/10.1084/jem.20021758

Published: 04 November 2002

View article titled, Mitochondrial Apoptosis and the Peripheral Benzodiazepine Receptor : <subtitle>A Novel Target for Viral and Pharmacological Manipulation </subtitle>

Journal Articles

Human Immunodeficiency Virus 1 Envelope Glycoprotein Complex-Induced Apoptosis Involves Mammalian Target of Rapamycin/Fkbp12-Rapamycin–Associated Protein–Mediated P53 Phosphorylation

Maria Castedo, Karine F. Ferri, Julià Blanco, Thomas Roumier, Nathanael Larochette, Jordi Barretina, Alessandra Amendola, Roberta Nardacci, Didier Métivier, José A. Este, Mauro Piacentini, Guido Kroemer

J Exp Med (2001) 194 (8): 1097–1110.

https://doi.org/10.1084/jem.194.8.1097

Published: 15 October 2001

View article titled, Human Immunodeficiency Virus 1 Envelope Glycoprotein Complex-Induced Apoptosis Involves Mammalian Target of Rapamycin/Fkbp12-Rapamycin–Associated Protein–Mediated P53 Phosphorylation

Journal Articles

Control of Mitochondrial Membrane Permeabilization by Adenine Nucleotide Translocator Interacting with HIV-1 Viral Protein R and Bcl-2

J Exp Med (2001) 193 (4): 509–520.

https://doi.org/10.1084/jem.193.4.509

Published: 20 February 2001

View article titled, Control of Mitochondrial Membrane Permeabilization by Adenine Nucleotide Translocator Interacting with HIV-1 Viral Protein R and Bcl-2

Journal Articles

Apoptosis Control in Syncytia Induced by the HIV Type 1–Envelope Glycoprotein Complex: Role of Mitochondria and Caspases

Karine F. Ferri, Etienne Jacotot, Julià Blanco, José A. Esté, Naoufal Zamzami, Santos A. Susin, Zhihua Xie, Greg Brothers, John C. Reed, Josef M. Penninger, Guido Kroemer

J Exp Med (2000) 192 (8): 1081–1092.

https://doi.org/10.1084/jem.192.8.1081

Published: 09 October 2000

View article titled, Apoptosis Control in Syncytia Induced by the HIV Type 1–Envelope Glycoprotein Complex: <subtitle>Role of Mitochondria and Caspases</subtitle>

Journal Articles

Two Distinct Pathways Leading to Nuclear Apoptosis

Santos A. Susin, Eric Daugas, Luigi Ravagnan, Kumiko Samejima, Naoufal Zamzami, Markus Loeffler, Paola Costantini, Karine F. Ferri, Theano Irinopoulou, Marie-Christine Prévost, Greg Brothers, Tak W. Mak, Josef Penninger, William C. Earnshaw, Guido Kroemer

J Exp Med (2000) 192 (4): 571–580.

https://doi.org/10.1084/jem.192.4.571

Published: 21 August 2000

View article titled, Two Distinct Pathways Leading to Nuclear Apoptosis

Journal Articles

The HIV-1 Viral Protein R Induces Apoptosis via a Direct Effect on the Mitochondrial Permeability Transition Pore

Etienne Jacotot, Luigi Ravagnan, Markus Loeffler, Karine F. Ferri, Helena L.A. Vieira, Naoufal Zamzami, Paola Costantini, Sabine Druillennec, Johan Hoebeke, Jean Paul Briand, Theano Irinopoulou, Eric Daugas, Santos A. Susin, Denis Cointe, Zhi Hua Xie, John C. Reed, Bernard P. Roques, Guido Kroemer

J Exp Med (2000) 191 (1): 33–46.

https://doi.org/10.1084/jem.191.1.33

Published: 03 January 2000

View article titled, The HIV-1 Viral Protein R Induces Apoptosis via a Direct Effect on the Mitochondrial Permeability Transition Pore

Journal Articles

Mitochondrial Release of Caspase-2 and -9 during the Apoptotic Process

Santos A. Susin, Hans K. Lorenzo, Naoufal Zamzami, Isabel Marzo, Catherine Brenner, Nathanael Larochette, Marie-Christine Prévost, Pedro M. Alzari, Guido Kroemer

J Exp Med (1999) 189 (2): 381–394.

https://doi.org/10.1084/jem.189.2.381

Published: 18 January 1999

View article titled, Mitochondrial Release of Caspase-2 and -9 during the Apoptotic Process

NARROW

Autoimmunity affecting the biliary tract fuels the immunosurveillance of cholangiocarcinoma

Ferroptosis in infection, inflammation, and immunity

Immune checkpoint inhibitors

Effects of interleukin-2 in immunostimulation and immunosuppression

Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia

Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

Tumor cells convert immature myeloid dendritic cells into TGF-β–secreting cells inducing CD4⁺CD25⁺ regulatory T cell proliferation

Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope

NF-κB and p53 Are the Dominant Apoptosis-inducing Transcription Factors Elicited by the HIV-1 Envelope

Lysosomal Membrane Permeabilization Induces Cell Death in a Mitochondrion-dependent Fashion

Mitochondrial Apoptosis and the Peripheral Benzodiazepine Receptor : A Novel Target for Viral and Pharmacological Manipulation

Human Immunodeficiency Virus 1 Envelope Glycoprotein Complex-Induced Apoptosis Involves Mammalian Target of Rapamycin/Fkbp12-Rapamycin–Associated Protein–Mediated P53 Phosphorylation

Control of Mitochondrial Membrane Permeabilization by Adenine Nucleotide Translocator Interacting with HIV-1 Viral Protein R and Bcl-2

Apoptosis Control in Syncytia Induced by the HIV Type 1–Envelope Glycoprotein Complex: Role of Mitochondria and Caspases

Two Distinct Pathways Leading to Nuclear Apoptosis

The HIV-1 Viral Protein R Induces Apoptosis via a Direct Effect on the Mitochondrial Permeability Transition Pore

Mitochondrial Release of Caspase-2 and -9 during the Apoptotic Process

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