Issues

Contrasting sites for expression of MIP-3α and MIP-3β in human tonsils. In vivo MIP-3α (top) and MIP-3β (bottom) expression by in situ hybridization of tonsils. The two darkfield illuminations represent the same area (serial cryostat sections; original magnification: ×40). mRNA for MIP-3α (top) is detected at high levels in epithelial crypts only, whereas MIP-3β expression (bottom) is restricted to T cell–rich areas. MIP-3α and MIP-3β attract immature and mature dendritic cells, respectively. See related article in this issue by Dieu et al., pp. 373–386.