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Keith B. Elkon
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Journal Articles

TLR7/8 activation in neutrophils impairs immune complex phagocytosis through shedding of FcgRIIA

Christian Lood, Sabine Arve, Jeffrey Ledbetter, Keith B. Elkon
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (7): 2103–2119.
https://doi.org/10.1084/jem.20161512
Published: 12 June 2017
View articletitled, TLR7/8 activation in neutrophils impairs immune complex phagocytosis through shedding of FcgRIIA
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Journal Articles

Genetic evidence for the role of plasmacytoid dendritic cells in systemic lupus erythematosus

Vanja Sisirak, Dipyaman Ganguly, Kanako L. Lewis, Coline Couillault, Lena Tanaka, Silvia Bolland, Vivette D’Agati, Keith B. Elkon, Boris Reizis
Journal: Journal of Experimental Medicine
J Exp Med (2014) 211 (10): 1969–1976.
https://doi.org/10.1084/jem.20132522
Published: 01 September 2014
View articletitled, Genetic evidence for the role of plasmacytoid dendritic cells in systemic lupus erythematosus
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Includes: Supplementary data
Journal Articles

Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells

Natalia V. Giltiay, Craig P. Chappell, Xizhang Sun, Nikita Kolhatkar, Thomas H. Teal, Alice E. Wiedeman, Jinoh Kim, Lena Tanaka, Matthew B. Buechler, Jessica A. Hamerman, Thereza Imanishi-Kari, Edward A. Clark, Keith B. Elkon
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (12): 2773–2789.
https://doi.org/10.1084/jem.20122798
Published: 21 October 2013
View articletitled, Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells
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Includes: Supplementary data
Journal Articles

Autoantibodies make a U-turn : the toll hypothesis for autoantibody specificity

David A. Martin, Keith B. Elkon
Journal: Journal of Experimental Medicine
J Exp Med (2005) 202 (11): 1465–1469.
https://doi.org/10.1084/jem.20052228
Published: 05 December 2005
View articletitled, Autoantibodies make a U-turn : the toll hypothesis for autoantibody specificity
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Journal Articles

I-PLA2 Activation during Apoptosis Promotes the Exposure of Membrane Lysophosphatidylcholine Leading to Binding by Natural Immunoglobulin M Antibodies and Complement Activation

Sun Jun Kim, Debra Gershov, Xiaojing Ma, Nathan Brot, Keith B. Elkon
Journal: Journal of Experimental Medicine
J Exp Med (2002) 196 (5): 655–665.
https://doi.org/10.1084/jem.20020542
Published: 26 August 2002
View articletitled, I-PLA2 Activation during Apoptosis Promotes the Exposure of Membrane Lysophosphatidylcholine Leading to Binding by Natural Immunoglobulin M Antibodies and Complement Activation
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Journal Articles

C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from Assembly of the Terminal Complement Components, and Sustains an Antiinflammatory Innate Immune Response: Implications for Systemic Autoimmunity

Debra Gershov, SunJung Kim, Nathan Brot, Keith B. Elkon
Journal: Journal of Experimental Medicine
J Exp Med (2000) 192 (9): 1353–1364.
https://doi.org/10.1084/jem.192.9.1353
Published: 06 November 2000
View articletitled, C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from Assembly of the Terminal Complement Components, and Sustains an Antiinflammatory Innate Immune Response: Implications for Systemic Autoimmunity
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Journal Articles

Caspases: Multifunctional Proteases

Keith B. Elkon
Journal: Journal of Experimental Medicine
J Exp Med (1999) 190 (12): 1725–1728.
https://doi.org/10.1084/jem.190.12.1725
Published: 20 December 1999
View articletitled, Caspases: Multifunctional Proteases
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Journal Articles

Complement-dependent Clearance of Apoptotic Cells by Human Macrophages

Dror Mevorach, John O. Mascarenhas, Debra Gershov, Keith B. Elkon
Journal: Journal of Experimental Medicine
J Exp Med (1998) 188 (12): 2313–2320.
https://doi.org/10.1084/jem.188.12.2313
Published: 21 December 1998
View articletitled, Complement-dependent Clearance of Apoptotic Cells by Human Macrophages
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Journal Articles

Systemic Exposure to Irradiated Apoptotic Cells Induces Autoantibody Production

Dror Mevorach, Jun Liang Zhou, Xin Song, Keith B. Elkon
Journal: Journal of Experimental Medicine
J Exp Med (1998) 188 (2): 387–392.
https://doi.org/10.1084/jem.188.2.387
Published: 20 July 1998
View articletitled, Systemic Exposure to Irradiated Apoptotic Cells Induces Autoantibody Production
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