(Left) Ribbons diagram of the complex between a T cell receptor (TCR) Vβ domain (yellow) and the bacterial superantigen staphylococcal enterotoxin C3 (SEC3; gray). (Right) The TCR Vβ–SEC3 complex opened like a book along a horizontal axis to show the interacting surfaces between the components. The Vβ CDR loops are colored as follows: CDR1, dark blue; CDR2, red; and CDR3, light blue; Vβ HV4, green. SEC3 residues are color coded according to their relative energetic contribution to binding the TCR β chain: red, >2.5 kcal/mol (most important); yellow, 1.5–2.5 kcal/mol; green, 0.5–1.5 kcal/mol; blue, <0.5 kcal/mol (least important). See related article in this issue by Leder et al., pp. 823–833.
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A Mutational Analysis of the Binding of Staphylococcal Enterotoxins B and C3 to the T Cell Receptor β Chain and Major Histocompatibility Complex Class II
The Unenlarged Lymph Nodes of HIV-1–infected, Asymptomatic Patients with High CD4 T Cell Counts Are Sites for Virus Replication and CD4 T Cell Proliferation. The Impact of Highly Active Antiretroviral Therapy
Brief Definitive Report
Transforming Growth Factor β1, in the Presence of Granulocyte/Macrophage Colony-stimulating Factor and Interleukin 4, Induces Differentiation of Human Peripheral Blood Monocytes into Dendritic Langerhans Cells
The Transcription Factor Interferon Regulatory Factor 1 (IRF-1) Is Important during the Maturation of Natural Killer 1.1+ T Cell Receptor–α/β+ (NK1+ T) Cells, Natural Killer Cells, and Intestinal Intraepithelial T Cells