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Journal Articles

Shp1 regulates T cell homeostasis by limiting IL-4 signals

Dylan J. Johnson, Lily I. Pao, Salim Dhanji, Kiichi Murakami, Pamela S. Ohashi, Benjamin G. Neel

J Exp Med (2013) 210 (7): 1419–1431.

https://doi.org/10.1084/jem.20122239

Published: 24 June 2013

View article titled, Shp1 regulates T cell homeostasis by limiting IL-4 signals

Journal Articles

The E3 ubiquitin ligase Mule acts through the ATM–p53 axis to maintain B lymphocyte homeostasis

J Exp Med (2012) 209 (1): 173–186.

https://doi.org/10.1084/jem.20111363

Published: 02 January 2012

View article titled, The E3 ubiquitin ligase Mule acts through the ATM–p53 axis to maintain B lymphocyte homeostasis

Journal Articles

Loss of the signaling adaptor TRAF1 causes CD8⁺ T cell dysregulation during human and murine chronic infection

J Exp Med (2011) 209 (1): 77–91.

https://doi.org/10.1084/jem.20110675

Published: 19 December 2011

View article titled, Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection

Includes: Supplementary data

Journal Articles

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

Shintaro Kamizono, Gordon S. Duncan, Markus G. Seidel, Akira Morimoto, Koichi Hamada, Gerard Grosveld, Koichi Akashi, Evan F. Lind, Jillian P. Haight, Pamela S. Ohashi, A. Thomas Look, Tak W. Mak

J Exp Med (2009) 206 (13): 2977–2986.

https://doi.org/10.1084/jem.20092176

Published: 07 December 2009

View article titled, Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

Includes: Supplementary data

Journal Articles

PKCθ Signals Activation versus Tolerance In Vivo

Nancy N. Berg-Brown, Matthew A. Gronski, Russell G. Jones, Alisha R. Elford, Elissa K. Deenick, Bernhard Odermatt, Dan R. Littman, Pamela S. Ohashi

J Exp Med (2004) 199 (6): 743–752.

https://doi.org/10.1084/jem.20031022

Published: 15 March 2004

View article titled, PKCθ Signals Activation versus Tolerance In Vivo

Journal Articles

CD28-dependent Activation of Protein Kinase B/Akt Blocks Fas-mediated Apoptosis by Preventing Death-inducing Signaling Complex Assembly

Russell G. Jones, Alisha R. Elford, Michael J. Parsons, Linda Wu, Connie M. Krawczyk, Wen-Chen Yeh, Razqallah Hakem, Robert Rottapel, James R. Woodgett, Pamela S. Ohashi

J Exp Med (2002) 196 (3): 335–348.

https://doi.org/10.1084/jem.20020307

Published: 05 August 2002

View article titled, CD28-dependent Activation of Protein Kinase B/Akt Blocks Fas-mediated Apoptosis by Preventing Death-inducing Signaling Complex Assembly

Journal Articles

The Immune Regulatory Function of Lymphoproliferative Double Negative T Cells In Vitro and In Vivo

Megan S. Ford, Kevin J. Young, Zhuxu Zhang, Pamela S. Ohashi, Li Zhang

J Exp Med (2002) 196 (2): 261–267.

https://doi.org/10.1084/jem.20020029

Published: 15 July 2002

View article titled, The Immune Regulatory Function of Lymphoproliferative Double Negative T Cells In Vitro and In Vivo

Journal Articles

Tumor Growth Enhances Cross-Presentation Leading to Limited T Cell Activation without Tolerance

Linh T. Nguyen, Alisha R. Elford, Kiichi Murakami, Kristine M. Garza, Stephen P. Schoenberger, Bernhard Odermatt, Daniel E. Speiser, Pamela S. Ohashi

J Exp Med (2002) 195 (4): 423–435.

https://doi.org/10.1084/jem.20010032

Published: 11 February 2002

View article titled, Tumor Growth Enhances Cross-Presentation Leading to Limited T Cell Activation without Tolerance

Journal Articles

Negative Regulation of T Cell Proliferation and Interleukin 2 Production by the Serine Threonine Kinase Gsk-3

Toshiaki Ohteki, Michael Parsons, Arsen Zakarian, Russell G. Jones, Linh T. Nguyen, James R. Woodgett, Pamela S. Ohashi

J Exp Med (2000) 192 (1): 99–104.

https://doi.org/10.1084/jem.192.1.99

Published: 03 July 2000

View article titled, Negative Regulation of T Cell Proliferation and Interleukin 2 Production by the Serine Threonine Kinase Gsk-3

Journal Articles

Protein Kinase B Regulates T Lymphocyte Survival, Nuclear Factor κb Activation, and Bcl-X_L Levels in Vivo

Russell G. Jones, Michael Parsons, Madeleine Bonnard, Vera S.F. Chan, Wen-Chen Yeh, James R. Woodgett, Pamela S. Ohashi

J Exp Med (2000) 191 (10): 1721–1734.

https://doi.org/10.1084/jem.191.10.1721

Published: 15 May 2000

View article titled, Protein Kinase B Regulates T Lymphocyte Survival, Nuclear Factor κb Activation, and Bcl-XL Levels in Vivo

Journal Articles

Differential Roles of Interleukin 15 mRNA Isoforms Generated by Alternative Splicing in Immune Responses in Vivo

Hitoshi Nishimura, Toshiki Yajima, Yoshikazu Naiki, Hironaka Tsunobuchi, Masayuki Umemura, Keiko Itano, Tetsuya Matsuguchi, Misao Suzuki, Pamela S. Ohashi, Yasunobu Yoshikai

J Exp Med (2000) 191 (1): 157–170.

https://doi.org/10.1084/jem.191.1.157

Published: 03 January 2000

View article titled, Differential Roles of Interleukin 15 mRNA Isoforms Generated by Alternative Splicing in Immune Responses in Vivo

Journal Articles

Role of Antigen-Presenting Cells in Mediating Tolerance and Autoimmunity

Kristine M. Garza, Steven M. Chan, Rakesh Suri, Linh T. Nguyen, Bernhard Odermatt, Stephen P. Schoenberger, Pamela S. Ohashi

J Exp Med (1999) 191 (11): 2021–2028.

https://doi.org/10.1084/jem.191.11.2021

Published: 06 June 1999

View article titled, Role of Antigen-Presenting Cells in Mediating Tolerance and Autoimmunity

Journal Articles

Vav Regulates Peptide-specific Apoptosis in Thymocytes

Young-Yun Kong, Klaus-Dieter Fischer, Martin F. Bachmann, Sanjeev Mariathasan, Ivona Kozieradzki, Mai P. Nghiem, Dennis Bouchard, Alan Bernstein, Pamela S. Ohashi, Josef M. Penninger

J Exp Med (1998) 188 (11): 2099–2111.

https://doi.org/10.1084/jem.188.11.2099

Published: 07 December 1998

View article titled, Vav Regulates Peptide-specific Apoptosis in Thymocytes

Journal Articles

The Inositol Polyphosphate 5-Phosphatase Ship Is a Crucial Negative Regulator of B Cell Antigen Receptor Signaling

Qiurong Liu, Antonio J. Oliveira-Dos-Santos, Sanjeev Mariathasan, Denis Bouchard, Jamie Jones, Renu Sarao, Ivona Kozieradzki, Pamela S. Ohashi, Josef M. Penninger, Daniel J. Dumont

J Exp Med (1998) 188 (7): 1333–1342.

https://doi.org/10.1084/jem.188.7.1333

Published: 05 October 1998

View article titled, The Inositol Polyphosphate 5-Phosphatase Ship Is a Crucial Negative Regulator of B Cell Antigen Receptor Signaling

Journal Articles

The Transcription Factor Interferon Regulatory Factor 1 (IRF-1) Is Important during the Maturation of Natural Killer 1.1⁺ T Cell Receptor–α/β⁺ (NK1⁺ T) Cells, Natural Killer Cells, and Intestinal Intraepithelial T Cells

Toshiaki Ohteki, Hiroki Yoshida, Toshifumi Matsuyama, Gordon S. Duncan, Tak W. Mak, Pamela S. Ohashi

J Exp Med (1998) 187 (6): 967–972.

https://doi.org/10.1084/jem.187.6.967

Published: 16 March 1998

View article titled, The Transcription Factor Interferon Regulatory Factor 1 (IRF-1) Is Important during the Maturation of Natural Killer 1.1+ T Cell Receptor–α/β+ (NK1+ T) Cells, Natural Killer Cells, and Intestinal Intraepithelial T Cells

Journal Articles

Impaired CD28-mediated Interleukin 2 Production and Proliferation in Stress Kinase SAPK/ERK1 Kinase (SEK1)/Mitogen-activated Protein Kinase Kinase 4 (MKK4)-deficient T Lymphocytes

Hiroshi Nishina, Martin Bachmann, Antonio J. Oliveira-dos-Santos, Ivona Kozieradzki, Klaus D. Fischer, Bernhard Odermatt, Andrew Wakeham, Arda Shahinian, Hiroaki Takimoto, Alan Bernstein, Tak W. Mak, James R. Woodgett, Pamela S. Ohashi, Josef M. Penninger

J Exp Med (1997) 186 (6): 941–953.

https://doi.org/10.1084/jem.186.6.941

Published: 15 September 1997

View article titled, Impaired CD28-mediated Interleukin 2 Production and Proliferation in Stress Kinase SAPK/ERK1 Kinase (SEK1)/Mitogen-activated Protein Kinase Kinase 4 (MKK4)-deficient T Lymphocytes

Journal Articles

Self Antigens Expressed by Solid Tumors Do Not Efficiently Stimulate Naive or Activated T Cells: Implications for Immunotherapy

Daniel E. Speiser, Renata Miranda, Arsen Zakarian, Martin F. Bachmann, Kim McKall-Faienza, Bernhard Odermatt, Douglas Hanahan, Rolf M. Zinkernagel, Pamela S. Ohashi

J Exp Med (1997) 186 (5): 645–653.

https://doi.org/10.1084/jem.186.5.645

Published: 29 August 1997

View article titled, Self Antigens Expressed by Solid Tumors Do Not Efficiently Stimulate Naive or Activated T Cells: Implications for Immunotherapy

Journal Articles

A Regulatory Role for TRAF1 in Antigen-induced Apoptosis of T Cells

Daniel E. Speiser, Soo Young Lee, Brian Wong, Joseph Arron, Angela Santana, Young-Yun Kong, Pamela S. Ohashi, Yongwon Choi

J Exp Med (1997) 185 (10): 1777–1783.

https://doi.org/10.1084/jem.185.10.1777

Published: 19 May 1997

View article titled, A Regulatory Role for TRAF1 in Antigen-induced Apoptosis of T Cells

NARROW

Shp1 regulates T cell homeostasis by limiting IL-4 signals

The E3 ubiquitin ligase Mule acts through the ATM–p53 axis to maintain B lymphocyte homeostasis

Loss of the signaling adaptor TRAF1 causes CD8⁺ T cell dysregulation during human and murine chronic infection

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

PKCθ Signals Activation versus Tolerance In Vivo

CD28-dependent Activation of Protein Kinase B/Akt Blocks Fas-mediated Apoptosis by Preventing Death-inducing Signaling Complex Assembly

The Immune Regulatory Function of Lymphoproliferative Double Negative T Cells In Vitro and In Vivo

Tumor Growth Enhances Cross-Presentation Leading to Limited T Cell Activation without Tolerance

Negative Regulation of T Cell Proliferation and Interleukin 2 Production by the Serine Threonine Kinase Gsk-3

Protein Kinase B Regulates T Lymphocyte Survival, Nuclear Factor κb Activation, and Bcl-X_L Levels in Vivo

Differential Roles of Interleukin 15 mRNA Isoforms Generated by Alternative Splicing in Immune Responses in Vivo

Role of Antigen-Presenting Cells in Mediating Tolerance and Autoimmunity

Vav Regulates Peptide-specific Apoptosis in Thymocytes

The Inositol Polyphosphate 5-Phosphatase Ship Is a Crucial Negative Regulator of B Cell Antigen Receptor Signaling

The Transcription Factor Interferon Regulatory Factor 1 (IRF-1) Is Important during the Maturation of Natural Killer 1.1⁺ T Cell Receptor–α/β⁺ (NK1⁺ T) Cells, Natural Killer Cells, and Intestinal Intraepithelial T Cells

Impaired CD28-mediated Interleukin 2 Production and Proliferation in Stress Kinase SAPK/ERK1 Kinase (SEK1)/Mitogen-activated Protein Kinase Kinase 4 (MKK4)-deficient T Lymphocytes

Self Antigens Expressed by Solid Tumors Do Not Efficiently Stimulate Naive or Activated T Cells: Implications for Immunotherapy

A Regulatory Role for TRAF1 in Antigen-induced Apoptosis of T Cells

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