Cell trafficking into livers of mice infected with murine cytomegalovirus (MCMV). Natural killer (NK) cells mediate defense against MCMV in these tissues. Transferred fluorescently labeled populations (red/yellow) accumulate in infected livers as either inflammatory focal populations or individual cells in sinusoidal regions. NK cells comprise the major focal population. This accumulation is infection-induced and MIP-1α dependent, whereas the sinusoidal trafficking is constitutive and derived from monocyte/macrophage lineage cells. See related article in this issue by Salazar-Mather et al., pp. 1–14.
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The Class I Antigen-processing Pathway for the Membrane Protein Tyrosinase Involves Translation in the Endoplasmic Reticulum and Processing in the Cytosol
Brief Definitive Report
Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s