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New insights into the mobilization and phagocytic activity of dendritic cells.

J M Austyn

View Articletitled, New insights into the mobilization and phagocytic activity of dendritic cells.

Apoptosis: mitochondria resurrected?

P A Henkart,S Grinstein

View Articletitled, Apoptosis: mitochondria resurrected?

Primary allergic sensitization to environmental antigens: perinatal T cell priming as a determinant of responder phenotype in adulthood.

P G Holt

View Articletitled, Primary allergic sensitization to environmental antigens: perinatal T cell priming as a determinant of responder phenotype in adulthood.

Article

Central role of immunoglobulin (Ig) E in the induction of lung eosinophil infiltration and T helper 2 cell cytokine production: inhibition by a non-anaphylactogenic anti-IgE antibody.

A J Coyle,K Wagner,C Bertrand,S Tsuyuki,J Bews,C Heusser

View Articletitled, Central role of immunoglobulin (Ig) E in the induction of lung eosinophil infiltration and T helper 2 cell cytokine production: inhibition by a non-anaphylactogenic anti-IgE antibody.

Endogenous altered peptide ligands can affect peripheral T cell responses.

K Vidal,B L Hsu,C B Williams,P M Allen

View Articletitled, Endogenous altered peptide ligands can affect peripheral T cell responses.

The altered tumoricidal capacity of macrophages isolated from tumor-bearing mice is related to reduce expression of the inducible nitric oxide synthase gene.

M R Dinapoli,C L Calderon,D M Lopez

View Articletitled, The altered tumoricidal capacity of macrophages isolated from tumor-bearing mice is related to reduce expression of the inducible nitric oxide synthase gene.

Major histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin L.

T Bevec,V Stoka,G Pungercic,I Dolenc,V Turk

View Articletitled, Major histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin L.

CD4+ T cell activation and tolerance induction in B cell knockout mice.

J A Phillips,C G Romball,M V Hobbs,D N Ernst,L Shultz,W O Weigle

View Articletitled, CD4+ T cell activation and tolerance induction in B cell knockout mice.

Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans.

L Romani,A Mencacci,E Cenci,R Spaccapelo,C Toniatti,P Puccetti,F Bistoni,V Poli

View Articletitled, Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans.

Therapy of murine tumors with p53 wild-type and mutant sequence peptide-based vaccines.

J I Mayordomo,D J Loftus,H Sakamoto,C M De Cesare,P M Appasamy,M T Lotze,W J Storkus,E Appella,A B DeLeo

View Articletitled, Therapy of murine tumors with p53 wild-type and mutant sequence peptide-based vaccines.

Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts.

C Zimmerman,K Brduscha-Riem,C Blaser,R M Zinkernagel,H Pircher

View Articletitled, Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts.

Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis.

C Lagresle,P Mondière,C Bella,P H Krammer,T Defrance

View Articletitled, Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis.

Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA.

G S Gilkeson,P Ruiz,A M Pippen,A L Alexander,J B Lefkowith,D S Pisetsky

View Articletitled, Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA.

The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6.

M Peters,S Jacobs,M Ehlers,P Vollmer,J Müllberg,E Wolf,G Brem,K H Meyer zum Büschenfelde,S Rose-John

View Articletitled, The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6.

Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils.

S Yousefi,D C Hoessli,K Blaser,G B Mills,H U Simon

View Articletitled, Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils.

LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor.

R Schmits,T M Kündig,D M Baker,G Shumaker,J J Simard,G Duncan,A Wakeham,A Shahinian,A van der Heiden,M F Bachmann,P S Ohashi,T W Mak,D D Hickstein

View Articletitled, LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor.

Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone.

L P Shornick,P De Togni,S Mariathasan,J Goellner,J Strauss-Schoenberger,R W Karr,T A Ferguson,D D Chaplin

View Articletitled, Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone.

Different superantigens interact with distinct sites in the Vbeta domain of a single T cell receptor.

S C Hong,G Waterbury,C A Janeway, Jr

View Articletitled, Different superantigens interact with distinct sites in the Vbeta domain of a single T cell receptor.

The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice.

F P Huang,G J Feng,G Lindop,D I Stott,F Y Liew

View Articletitled, The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice.

Chronic inflammation caused by lymphotoxin is lymphoid neogenesis.

A Kratz,A Campos-Neto,M S Hanson,N H Ruddle

View Articletitled, Chronic inflammation caused by lymphotoxin is lymphoid neogenesis.

Distinct regulatory roles of lymphocyte costimulatory pathways on T helper type-2 mediated autoimmune disease.

L Biancone,G Andres,H Ahn,A Lim,C Dai,R Noelle,H Yagita,C De Martino,I Stamenkovic

View Articletitled, Distinct regulatory roles of lymphocyte costimulatory pathways on T helper type-2 mediated autoimmune disease.

Resistance to cutaneous graft-vs.-host disease is not induced in T cell receptor delta gene-mutant mice.

T Shiohara,N Moriya,J Hayakawa,S Itohara,H Ishikawa

View Articletitled, Resistance to cutaneous graft-vs.-host disease is not induced in T cell receptor delta gene-mutant mice.

Localization of DNA damage and its role in altered antigen-presenting cell function in ultraviolet-irradiated mice.

A A Vink,F M Strickland,C Bucana,P A Cox,L Roza,D B Yarosh,M L Kripke

View Articletitled, Localization of DNA damage and its role in altered antigen-presenting cell function in ultraviolet-irradiated mice.

Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase.

S Stenger,N Donhauser,H Thüring,M Röllinghoff,C Bogdan

View Articletitled, Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase.

Mechanisms of platelet-activating factor-induced lipid body formation: requisite roles for 5-lipoxygenase and de novo protein synthesis in the compartmentalization of neutrophil lipids.

P T Bozza,J L Payne,J L Goulet,P F Weller

View Articletitled, Mechanisms of platelet-activating factor-induced lipid body formation: requisite roles for 5-lipoxygenase and de novo protein synthesis in the compartmentalization of neutrophil lipids.

Exochelins of Mycobacterium tuberculosis remove iron from human iron-binding proteins and donate iron to mycobactins in the M. tuberculosis cell wall.

J Gobin,M A Horwitz

View Articletitled, Exochelins of Mycobacterium tuberculosis remove iron from human iron-binding proteins and donate iron to mycobactins in the M. tuberculosis cell wall.

Mitochondrial control of nuclear apoptosis.

N Zamzami,S A Susin,P Marchetti,T Hirsch,I Gómez-Monterrey,M Castedo,G Kroemer

View Articletitled, Mitochondrial control of nuclear apoptosis.

The requirement for proteasome activity class I major histocompatibility complex antigen presentation is dictated by the length of preprocessed antigen.

B Yang,Y S Hahn,C S Hahn,T J Braciale

View Articletitled, The requirement for proteasome activity class I major histocompatibility complex antigen presentation is dictated by the length of preprocessed antigen.

Recognition of class I major histocompatibility complex molecules by Ly-49: specificities and domain interactions.

J Brennan,G Mahon,D L Mager,W A Jefferies,F Takei

View Articletitled, Recognition of class I major histocompatibility complex molecules by Ly-49: specificities and domain interactions.

Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes.

J Tian,M A Atkinson,M Clare-Salzler,A Herschenfeld,T Forsthuber,P V Lehmann,D L Kaufman

View Articletitled, Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes.

The protease inhibitor, N-acetyl-L-leucyl-L-leucyl-leucyl-L-norleucinal, decreases the pool of major histocompatibility complex class I-binding peptides and inhibits peptide trimming in the endoplasmic reticulum.

E A Hughes,B Ortmann,M Surman,P Cresswell

View Articletitled, The protease inhibitor, N-acetyl-L-leucyl-L-leucyl-leucyl-L-norleucinal, decreases the pool of major histocompatibility complex class I-binding peptides and inhibits peptide trimming in the endoplasmic reticulum.

Localization of the binding site for the monocyte immunoglobulin (Ig) A-Fc receptor (CD89) to the domain boundary between Calpha2 and Calpha3 in human IgA1.

L Carayannopoulos,J M Hexham,J D Capra

View Articletitled, Localization of the binding site for the monocyte immunoglobulin (Ig) A-Fc receptor (CD89) to the domain boundary between Calpha2 and Calpha3 in human IgA1.

Metabolism of Tac (IL2Ralpha): physiology of cell surface shedding and renal catabolism, and suppression of catabolism by antibody binding.

R P Junghans,T A Waldmann

View Articletitled, Metabolism of Tac (IL2Ralpha): physiology of cell surface shedding and renal catabolism, and suppression of catabolism by antibody binding.

Major histocompatibility complex class II-expressing endothelial cells induce allospecific nonresponsiveness in naive T cells.

F M Marelli-Berg,R E Hargreaves,P Carmichael,A Dorling,G Lombardi,R I Lechler

View Articletitled, Major histocompatibility complex class II-expressing endothelial cells induce allospecific nonresponsiveness in naive T cells.

Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation: implications for antibody vs. T cell-mediated autoimmunity.

R R Singh,B H Hahn,E E Sercarz

View Articletitled, Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation: implications for antibody vs. T cell-mediated autoimmunity.

Rabies superantigen as a Vbeta T-dependent adjuvant.

E Astoul,M Lafage,M Lafon

View Articletitled, Rabies superantigen as a Vbeta T-dependent adjuvant.

5(S),15(S)-dihydroxyeicosatetraenoic acid and lipoxin generation in human polymorphonuclear cells: dual specificity of 5-lipoxygenase towards endogenous and exogenous precursors.

C Chavis,I Vachier,P Chanez,J Bousquet,P Godard

View Articletitled, 5(S),15(S)-dihydroxyeicosatetraenoic acid and lipoxin generation in human polymorphonuclear cells: dual specificity of 5-lipoxygenase towards endogenous and exogenous precursors.

Infection of human immunodeficiency virus 1 transgenic mice with Toxoplasma gondii stimulates proviral transcription in macrophages in vivo.

R T Gazzinelli,A Sher,A Cheever,S Gerstberger,M A Martin,P Dickie

View Articletitled, Infection of human immunodeficiency virus 1 transgenic mice with Toxoplasma gondii stimulates proviral transcription in macrophages in vivo.

Breaking self-tolerance in nonobese diabetic mice.

W M Ridgway,M Fassò,A Lanctot,C Garvey,C G Fathman

View Articletitled, Breaking self-tolerance in nonobese diabetic mice.

Soluble hyaluronan receptor RHAMM induces mitotic arrest by suppressing Cdc2 and cyclin B1 expression.

S Mohapatra,X Yang,J A Wright,E A Turley,A H Greenberg

View Articletitled, Soluble hyaluronan receptor RHAMM induces mitotic arrest by suppressing Cdc2 and cyclin B1 expression.

T cell receptor usage and fine specificity of human immunodeficiency virus 1-specific cytotoxic T lymphocyte clones: analysis of quasispecies recognition reveals a dominant response directed against a minor in vivo variant.

S A Kalams,R P Johnson,M J Dynan,K E Hartman,T Harrer,E Harrer,A K Trocha,W A Blattner,S P Buchbinder,B D Walker

View Articletitled, T cell receptor usage and fine specificity of human immunodeficiency virus 1-specific cytotoxic T lymphocyte clones: analysis of quasispecies recognition reveals a dominant response directed against a minor in vivo variant.

Human intestinal Vdelta1+ lymphocytes recognize tumor cells of epithelial origin.

M J Maeurer,D Martin,W Walter,K Liu,L Zitvogel,K Halusczcak,H Rabinowich,R Duquesnoy,W Storkus,M T Lotze

View Articletitled, Human intestinal Vdelta1+ lymphocytes recognize tumor cells of epithelial origin.

Distinct T cell receptor signaling requirements for perforin- or FasL-mediated cytotoxicity.

M T Esser,B Krishnamurthy,V L Braciale

View Articletitled, Distinct T cell receptor signaling requirements for perforin- or FasL-mediated cytotoxicity.

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation.

K F Byth,L A Conroy,S Howlett,A J Smith,J May,D R Alexander,N Holmes

View Articletitled, CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation.

Requirement for CD8+ T cells in the development of airway hyperresponsiveness in a marine model of airway sensitization.

E Hamelmann,A Oshiba,J Paluh,K Bradley,J Loader,T A Potter,G L Larsen,E W Gelfand

View Articletitled, Requirement for CD8+ T cells in the development of airway hyperresponsiveness in a marine model of airway sensitization.

The half-life of RAG-1 protein in precursor B cells is increased in the absence of RAG-2 expression.

U Grawunder,D G Schatz,T M Leu,A Rolink,F Melchers

View Articletitled, The half-life of RAG-1 protein in precursor B cells is increased in the absence of RAG-2 expression.

Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity.

D L Doolan,M Sedegah,R C Hedstrom,P Hobart,Y Charoenvit,S L Hoffman

View Articletitled, Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity.

Transcriptional regulation of the Icam-1 gene in antigen receptor- and phorbol ester-stimulated B lymphocytes: role for transcription factor EGR1.

J S Maltzman,J A Carmen,J G Monroe

View Articletitled, Transcriptional regulation of the Icam-1 gene in antigen receptor- and phorbol ester-stimulated B lymphocytes: role for transcription factor EGR1.

Patr-A and B, the orthologues of HLA-A and B, present hepatitis C virus epitopes to CD8+ cytotoxic T cells from two chronically infected chimpanzees.

H Kowalski,A L Erickson,S Cooper,J D Domena,P Parham,C M Walker

View Articletitled, Patr-A and B, the orthologues of HLA-A and B, present hepatitis C virus epitopes to CD8+ cytotoxic T cells from two chronically infected chimpanzees.

A predictable sequential determinant spreading cascade invariably accompanies progression of experimental autoimmune encephalomyelitis: a basis for peptide-specific therapy after onset of clinical disease.

M Yu,J M Johnson,V K Tuohy

View Articletitled, A predictable sequential determinant spreading cascade invariably accompanies progression of experimental autoimmune encephalomyelitis: a basis for peptide-specific therapy after onset of clinical disease.

A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis.

G Süss,K Shortman

View Articletitled, A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis.

Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.

M A Goodell,K Brose,G Paradis,A S Conner,R C Mulligan

View Articletitled, Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.

Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma.

H Hisamatsu,N Shimbara,Y Saito,P Kristensen,K B Hendil,T Fujiwara,E Takahashi,N Tanahashi,T Tamura,A Ichihara,K Tanaka

View Articletitled, Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma.

Heterogeneous phenotypes of expression of the NKB1 natural killer cell class I receptor among individuals of different human histocompatibility leukocyte antigens types appear genetically regulated, but not linked to major histocompatibililty complex haplotype.

J E Gumperz,N M Valiante,P Parham,L L Lanier,D Tyan

View Articletitled, Heterogeneous phenotypes of expression of the NKB1 natural killer cell class I receptor among individuals of different human histocompatibility leukocyte antigens types appear genetically regulated, but not linked to major histocompatibililty complex haplotype.

The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB.

H L Pahl,B Krauss,K Schulze-Osthoff,T Decker,E B Traenckner,M Vogt,C Myers,T Parks,P Warring,A Mühlbacher,A P Czernilofsky,P A Baeuerle

View Articletitled, The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB.

Inhibition of interleukin-1 responsiveness by type II receptor gene transfer: a surface "receptor" with anti-interleukin-1 function.

F Re,M Sironi,M Muzio,C Matteucci,M Introna,S Orlando,G Penton-Rol,S K Dower,J E Sims,F Colotta,A Mantovani

View Articletitled, Inhibition of interleukin-1 responsiveness by type II receptor gene transfer: a surface "receptor" with anti-interleukin-1 function.

The interaction of macrophage and non-macrophage tropic isolates of HIV-1 with thymic and tonsillar dendritic cells in vitro.

P U Cameron,M G Lowe,F Sotzik,A F Coughlan,S M Crowe,K Shortman

View Articletitled, The interaction of macrophage and non-macrophage tropic isolates of HIV-1 with thymic and tonsillar dendritic cells in vitro.

Antibody response to a T-dependent antigen requires B cell expression of complement receptors.

D A Croix,J M Ahearn,A M Rosengard,S Han,G Kelsoe,M Ma,M C Carroll

View Articletitled, Antibody response to a T-dependent antigen requires B cell expression of complement receptors.

A life stage of particle-laden rat dendritic cells in vivo: their terminal division, active phagocytosis, and translocation from the liver to the draining lymph.

K Matsuno,T Ezaki,S Kudo,Y Uehara

View Articletitled, A life stage of particle-laden rat dendritic cells in vivo: their terminal division, active phagocytosis, and translocation from the liver to the draining lymph.

Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cells.

T Zhou,J Cheng,P Yang,Z Wang,C Liu,X Su,H Bluethmann,J D Mountz

View Articletitled, Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cells.

Inhibition of leukotriene B4-receptor interaction suppresses eosinophil infiltration and disease pathology in a murine model of experimental allergic encephalomyelitis.

R P Gladue,L A Carroll,A J Milici,D N Scampoli,H A Stukenbrok,E R Pettipher,E D Salter,L Contillo,H J Showell

View Articletitled, Inhibition of leukotriene B4-receptor interaction suppresses eosinophil infiltration and disease pathology in a murine model of experimental allergic encephalomyelitis.

Association of mitogen-activated protein kinases with microtubules in mouse macrophages.

A Ding,B Chen,M Fuortes,E Blum

View Articletitled, Association of mitogen-activated protein kinases with microtubules in mouse macrophages.

Immunoglobulin G3 blocking antibodies to the fungal pathogen Cryptococcus neoformans.

G Nussbaum,R Yuan,A Casadevall,M D Scharff

View Articletitled, Immunoglobulin G3 blocking antibodies to the fungal pathogen Cryptococcus neoformans.

The beta subunit of human granulocyte-macrophage colony-stimulating factor receptor forms a homodimer and is activated via association with the alpha subunit.

A Muto,S Watanabe,A Miyajima,T Yokota,K Arai

View Articletitled, The beta subunit of human granulocyte-macrophage colony-stimulating factor receptor forms a homodimer and is activated via association with the alpha subunit.

Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.

S Valitutti,S Müller,M Dessing,A Lanzavecchia

View Articletitled, Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.

p53 prevents maturation to the CD4+CD8+ stage of thymocyte differentiation in the absence of T cell receptor rearrangement.

D Jiang,M J Lenardo,J C Zúñiga-Pflücker

View Articletitled, p53 prevents maturation to the CD4+CD8+ stage of thymocyte differentiation in the absence of T cell receptor rearrangement.

gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses.

K Fujihashi,J R McGhee,M N Kweon,M D Cooper,S Tonegawa,I Takahashi,T Hiroi,J Mestecky,H Kiyono

View Articletitled, gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses.

Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production.

D G Motto,S E Ross,J Wu,L R Hendricks-Taylor,G A Koretzky

View Articletitled, Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production.

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