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Journal Articles

Decreased tumor surveillance in perforin-deficient mice.

M E van den Broek, D Kägi, F Ossendorp, R Toes, S Vamvakas, W K Lutz, C J Melief, R M Zinkernagel, H Hengartner

J Exp Med (1996) 184 (5): 1781–1790.

https://doi.org/10.1084/jem.184.5.1781

Published: 01 November 1996

View article titled, Decreased tumor surveillance in perforin-deficient mice.

Journal Articles

Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity.

D Kägi, B Odermatt, P S Ohashi, R M Zinkernagel, H Hengartner

J Exp Med (1996) 183 (5): 2143–2152.

https://doi.org/10.1084/jem.183.5.2143

Published: 01 May 1996

View article titled, Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity.

Journal Articles

CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions.

A Oxenius, K A Campbell, C R Maliszewski, T Kishimoto, H Kikutani, H Hengartner, R M Zinkernagel, M F Bachmann

J Exp Med (1996) 183 (5): 2209–2218.

https://doi.org/10.1084/jem.183.5.2209

Published: 01 May 1996

View article titled, CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions.

Journal Articles

Induction of long-lived germinal centers associated with persisting antigen after viral infection.

M F Bachmann, B Odermatt, H Hengartner, R M Zinkernagel

J Exp Med (1996) 183 (5): 2259–2269.

https://doi.org/10.1084/jem.183.5.2259

Published: 01 May 1996

View article titled, Induction of long-lived germinal centers associated with persisting antigen after viral infection.

Journal Articles

Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts.

C Zimmerman, K Brduscha-Riem, C Blaser, R M Zinkernagel, H Pircher

J Exp Med (1996) 183 (4): 1367–1375.

https://doi.org/10.1084/jem.183.4.1367

Published: 01 April 1996

View article titled, Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts.

Journal Articles

Strictly transporter of antigen presentation (TAP)-dependent presentation of an immunodominant cytotoxic T lymphocyte epitope in the signal sequence of a virus protein.

J Hombach, H Pircher, S Tonegawa, R M Zinkernagel

J Exp Med (1995) 182 (5): 1615–1619.

https://doi.org/10.1084/jem.182.5.1615

Published: 01 November 1995

View article titled, Strictly transporter of antigen presentation (TAP)-dependent presentation of an immunodominant cytotoxic T lymphocyte epitope in the signal sequence of a virus protein.

Journal Articles

T cell priming versus T cell tolerance induced by synthetic peptides.

P Aichele, K Brduscha-Riem, R M Zinkernagel, H Hengartner, H Pircher

J Exp Med (1995) 182 (1): 261–266.

https://doi.org/10.1084/jem.182.1.261

Published: 01 July 1995

View article titled, T cell priming versus T cell tolerance induced by synthetic peptides.

Journal Articles

Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen.

S Oehen, H Waldner, T M Kündig, H Hengartner, R M Zinkernagel

J Exp Med (1992) 176 (5): 1273–1281.

https://doi.org/10.1084/jem.176.5.1273

Published: 01 November 1992

View article titled, Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen.

Journal Articles

Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny.

D E Speiser, H Pircher, P S Ohashi, D Kyburz, H Hengartner, R M Zinkernagel

J Exp Med (1992) 175 (5): 1277–1283.

https://doi.org/10.1084/jem.175.5.1277

Published: 01 May 1992

View article titled, Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny.

Journal Articles

Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression.

W P Fung-Leung, T M Kündig, R M Zinkernagel, T W Mak

J Exp Med (1991) 174 (6): 1425–1429.

https://doi.org/10.1084/jem.174.6.1425

Published: 01 December 1991

View article titled, Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression.

Journal Articles

Distinct fates of self-specific T cells developing in irradiation bone marrow chimeras: clonal deletion, clonal anergy, or in vitro responsiveness to self-Mls-1a controlled by hemopoietic cells in the thymus.

D E Speiser, Y Chvatchko, R M Zinkernagel, H R MacDonald

J Exp Med (1990) 172 (5): 1305–1314.

https://doi.org/10.1084/jem.172.5.1305

Published: 01 November 1990

View article titled, Distinct fates of self-specific T cells developing in irradiation bone marrow chimeras: clonal deletion, clonal anergy, or in vitro responsiveness to self-Mls-1a controlled by hemopoietic cells in the thymus.

Journal Articles

Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide.

P Aichele, H Hengartner, R M Zinkernagel, M Schulz

J Exp Med (1990) 171 (5): 1815–1820.

https://doi.org/10.1084/jem.171.5.1815

Published: 01 May 1990

View article titled, Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide.

Journal Articles

B cells are required for induction of T cell abnormalities in a murine retrovirus-induced immunodeficiency syndrome.

A Cerny, A W Hügin, R R Hardy, K Hayakawa, R M Zinkernagel, M Makino, H C Morse, 3rd

J Exp Med (1990) 171 (1): 315–320.

https://doi.org/10.1084/jem.171.1.315

Published: 01 January 1990

View article titled, B cells are required for induction of T cell abnormalities in a murine retrovirus-induced immunodeficiency syndrome.

Journal Articles

Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus.

D E Speiser, R K Lees, H Hengartner, R M Zinkernagel, H R MacDonald

J Exp Med (1989) 170 (6): 2165–2170.

https://doi.org/10.1084/jem.170.6.2165

Published: 01 December 1989

View article titled, Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus.

Journal Articles

Clonal deletion of self-reactive T cells in irradiation bone marrow chimeras and neonatally tolerant mice. Evidence for intercellular transfer of Mlsa.

D E Speiser, R Schneider, H Hengartner, H R MacDonald, R M Zinkernagel

J Exp Med (1989) 170 (2): 595–600.

https://doi.org/10.1084/jem.170.2.595

Published: 01 August 1989

View article titled, Clonal deletion of self-reactive T cells in irradiation bone marrow chimeras and neonatally tolerant mice. Evidence for intercellular transfer of Mlsa.

Journal Articles

Major histocompatibility complex-linked susceptibility or resistance to disease caused by a noncytopathic virus varies with the disease parameter evaluated.

T Leist, A Althage, E Haenseler, H Hengartner, R M Zinkernagel

J Exp Med (1989) 170 (1): 269–277.

https://doi.org/10.1084/jem.170.1.269

Published: 01 July 1989

View article titled, Major histocompatibility complex-linked susceptibility or resistance to disease caused by a noncytopathic virus varies with the disease parameter evaluated.

Journal Articles

Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity.

R Schneider, R K Lees, T Pedrazzini, R M Zinkernagel, H Hengartner, H R MacDonald

J Exp Med (1989) 169 (6): 2149–2158.

https://doi.org/10.1084/jem.169.6.2149

Published: 01 June 1989

View article titled, Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity.

Journal Articles

Thymic selection of H-2-incompatible bone marrow cells in SCID mice. Differences in T help for induction of B cell IgG responses versus cytotoxic T cells.

R M Zinkernagel, E Rüedi, A Althage, H Hengartner, G Reimann

J Exp Med (1988) 168 (3): 1187–1192.

https://doi.org/10.1084/jem.168.3.1187

Published: 01 September 1988

View article titled, Thymic selection of H-2-incompatible bone marrow cells in SCID mice. Differences in T help for induction of B cell IgG responses versus cytotoxic T cells.

Journal Articles

Production of B cell stimulatory factor-2 and interferon gamma in the central nervous system during viral meningitis and encephalitis. Evaluation in a murine model infection and in patients.

K Frei, T P Leist, A Meager, P Gallo, D Leppert, R M Zinkernagel, A Fontana

J Exp Med (1988) 168 (1): 449–453.

https://doi.org/10.1084/jem.168.1.449

Published: 01 July 1988

View article titled, Production of B cell stimulatory factor-2 and interferon gamma in the central nervous system during viral meningitis and encephalitis. Evaluation in a murine model infection and in patients.

Journal Articles

Intrathymic elimination of Mlsa-reactive (V beta 6+) cells during neonatal tolerance induction to Mlsa-encoded antigens.

H R MacDonald, T Pedrazzini, R Schneider, J A Louis, R M Zinkernagel, H Hengartner

J Exp Med (1988) 167 (6): 2005–2010.

https://doi.org/10.1084/jem.167.6.2005

Published: 01 June 1988

View article titled, Intrathymic elimination of Mlsa-reactive (V beta 6+) cells during neonatal tolerance induction to Mlsa-encoded antigens.

NARROW

Decreased tumor surveillance in perforin-deficient mice.

Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity.

CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions.

Induction of long-lived germinal centers associated with persisting antigen after viral infection.

Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts.

Strictly transporter of antigen presentation (TAP)-dependent presentation of an immunodominant cytotoxic T lymphocyte epitope in the signal sequence of a virus protein.

T cell priming versus T cell tolerance induced by synthetic peptides.

Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen.

Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny.

Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression.

Distinct fates of self-specific T cells developing in irradiation bone marrow chimeras: clonal deletion, clonal anergy, or in vitro responsiveness to self-Mls-1a controlled by hemopoietic cells in the thymus.

Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide.

B cells are required for induction of T cell abnormalities in a murine retrovirus-induced immunodeficiency syndrome.

Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus.

Clonal deletion of self-reactive T cells in irradiation bone marrow chimeras and neonatally tolerant mice. Evidence for intercellular transfer of Mlsa.

Major histocompatibility complex-linked susceptibility or resistance to disease caused by a noncytopathic virus varies with the disease parameter evaluated.

Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity.

Thymic selection of H-2-incompatible bone marrow cells in SCID mice. Differences in T help for induction of B cell IgG responses versus cytotoxic T cells.

Production of B cell stimulatory factor-2 and interferon gamma in the central nervous system during viral meningitis and encephalitis. Evaluation in a murine model infection and in patients.

Intrathymic elimination of Mlsa-reactive (V beta 6+) cells during neonatal tolerance induction to Mlsa-encoded antigens.

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