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24 August 2009
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XIST RNA (green) coats and inactivates one X chromosome (top left) but is released during mitosis (top right). Hall et al. find that Aurora B kinase regulates this association, and manipulate the kinase's activity to either release XIST during interphase (bottom left) or retain it in metaphase (bottom right). See page 491. - PDF Icon PDF LinkTable of Contents
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ISSN 0021-9525
EISSN 1540-8140
In this Issue
In This Issue
In Focus
Aurora B answers an XIST-ential question
Mitotic release of chromatin-binding RNA gives insight into X chromosome silencing.
People & Ideas
Alexander Meissner: Learning the reprogramming code
Meissner studies the epigenomics of pluripotent cells.
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