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23 March 2009
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EGF stimulates the small GTPase KRas (green) to move from the plasma membrane to late endosomes and lysosomes (red). KRas continues to signal from these compartments before being degraded.
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ISSN 0021-9525
EISSN 1540-8140
In this Issue
In This Issue
In Focus
Time (and PPARβ/δ) heals all wounds
Organotypic cultures help to unravel how a transcription factor modulates crosstalk between different layers of the skin.
People & Ideas
Marko Kaksonen: Tracking the inner secrets of endocytosis
Kaksonen is probing the function and regulation of the endocytic machinery in yeast using live-cell microscopy and genetics.
Review
Report
Article
Akt regulates L-type Ca2+ channel activity by modulating Cavα1 protein stability
Daniele Catalucci,Deng-Hong Zhang,Jaime DeSantiago,Franck Aimond,Guillaume Barbara,Jean Chemin,Désiré Bonci,Eckard Picht,Francesca Rusconi,Nancy D. Dalton,Kirk L. Peterson,Sylvain Richard,Donald M. Bers,Joan Heller Brown,Gianluigi Condorelli
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