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In This Issue

Huntington's disease protein extends its reach

Mitch Leslie
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Slow synapses in schizophrenia?

Mitch Leslie
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Dieting yeast clean house

Mitch Leslie
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Actin hitches a ride to the cleavage furrow

Mitch Leslie
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Synapse crowd control

Mitch Leslie
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Research Roundup

rDNA silencing saves starving cells

Richard Robinson
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Four proteins, two new cells

Richard Robinson
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Sweeter tumors with EGFR

Richard Robinson
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Abundance of ITAM prevents autoimmunity

Richard Robinson
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Robo keeps axons moving

Richard Robinson
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People & Ideas

Yasushi Saka: Stirring a melting pot of math and morphogens

Ruth Williams
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Review

Original CIN: reviewing roles for APC in chromosome instability

Nasser M. Rusan,Mark Peifer
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Report

Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis

Katherine Minter-Dykhouse,Irene Ward,Michael S.Y. Huen,Junjie Chen,Zhenkun Lou
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Reversible cytoplasmic localization of the proteasome in quiescent yeast cells

Damien Laporte,Bénédicte Salin,Bertrand Daignan-Fornier,Isabelle Sagot
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Article

Linking Ras to myosin function: RasGEF Q, a Dictyostelium exchange factor for RasB, affects myosin II functions

Subhanjan Mondal,Deenadayalan Bakthavatsalam,Paul Steimle,Berthold Gassen,Francisco Rivero,Angelika A. Noegel
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Desmin mediates TNF-α–induced aggregate formation and intercalated disk reorganization in heart failure

Panagiota Panagopoulou,Constantinos H. Davos,Derek J. Milner,Emily Varela,JoAnn Cameron,Douglas L. Mann,Yassemi Capetanaki
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Vesicles and actin are targeted to the cleavage furrow via furrow microtubules and the central spindle

Roger Albertson,Jian Cao,Tao-shih Hsieh,William Sullivan
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DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release

Xiao-Wei Chen,Ya-Qin Feng,Chan-Juan Hao,Xiao-Li Guo,Xin He,Zhi-Yong Zhou,Ning Guo,Hong-Ping Huang,Wei Xiong,Hui Zheng,Pan-Li Zuo,Claire Xi Zhang,Wei Li,Zhuan Zhou
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Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin

Chuan-En Wang,Hui Zhou,John R. McGuire,Vincenzo Cerullo,Brendan Lee,Shi-Hua Li,Xiao-Jiang Li
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Shootin1 interacts with actin retrograde flow and L1-CAM to promote axon outgrowth

Tadayuki Shimada,Michinori Toriyama,Kaori Uemura,Hiroyuki Kamiguchi,Tadao Sugiura,Naoki Watanabe,Naoyuki Inagaki
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Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis

Sergio Leal-Ortiz,Clarissa L. Waites,Ryan Terry-Lorenzo,Pedro Zamorano,Eckart D. Gundelfinger,Craig C. Garner
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The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching

Nicholas C. Kappas,Gefei Zeng,John C. Chappell,Joseph B. Kearney,Surovi Hazarika,Kimberly G. Kallianos,Cam Patterson,Brian H. Annex,Victoria L. Bautch
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P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis

Nattapon Panupinthu,Joseph T. Rogers,Lin Zhao,Luis Pastor Solano-Flores,Fred Possmayer,Stephen M. Sims,S. Jeffrey Dixon
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