Lipid droplets (LDs) store energy-rich fatty acids (FAs), but to harvest them, LDs donate FAs to peroxisomes for oxidation. In this issue, Chang et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201902061) identify M1 Spastin as an LD–peroxisome tether that interacts with ESCRT-III components to facilitate lipid exchange between these two organelles.
Spotlight| July 05 2019
Spastin joins LDs and peroxisomes in the interorganelle contact ballet
W. Mike Henne
Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX
Correspondence to W. Mike Henne: email@example.com
J Cell Biol (2019) 218 (8): 2439–2441.
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W. Mike Henne; Spastin joins LDs and peroxisomes in the interorganelle contact ballet. J Cell Biol 5 August 2019; 218 (8): 2439–2441. doi: https://doi.org/10.1083/jcb.201906025
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