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Mitochondrially tethered Mmm1 can function as a sole lipid transporter at ER–mitochondria contacts

Christian Covill-Cooke, Takashi Hirashima, Shin Kawano, Joe Ganellin, Andrew Moody, Sabine N.S. van Schie, Arun T. John Peter, Chika Horie Saito, Toshiya Endo, Benoît Kornmann

J Cell Biol (2026) 225 (7): e202411196.

https://doi.org/10.1083/jcb.202411196

Published: 07 May 2026

View article titled, Mitochondrially tethered Mmm1 can function as a sole lipid transporter at ER–mitochondria contacts

Includes: Supplementary data

Journal Articles

NASP functions in the cytoplasm to prevent histone H3 aggregation during early embryogenesis

Mohit Das, Eli Coronado-Chavez, Anusha D. Bhatt, Reyhaneh Tirgar, Amanda A. Amodeo, Jared T. Nordman

J Cell Biol (2026) 225 (7): e202511182.

https://doi.org/10.1083/jcb.202511182

Published: 06 May 2026

View article titled, NASP functions in the cytoplasm to prevent histone H3 aggregation during early embryogenesis

Includes: Supplementary data

Journal Articles

Time-resolved tmFRET reveals GTP-coupled conformational changes in Mfn1

Sophie M. Hurwitz, William N. Zagotta, Sharona E. Gordon, Suzanne Hoppins

J Cell Biol (2026) 225 (7): e202511077.

https://doi.org/10.1083/jcb.202511077

Published: 04 May 2026

View article titled, Time-resolved tmFRET reveals GTP-coupled conformational changes in Mfn1

Includes: Supplementary data

Journal Articles

Divergent Rickettsia species exhibit distinct mechanisms of actin-based motility

Meghan C. Bacher, Julie E. Choe, Jiawen Jiang, Joanna M. Idrovo, Joshua T. Del Mundo, Michal Hammel, Matthew D. Welch

J Cell Biol (2026) 225 (7): e202508117.

https://doi.org/10.1083/jcb.202508117

Published: 28 April 2026

View article titled, Divergent Rickettsia species exhibit distinct mechanisms of actin-based motility

Includes: Supplementary data

Journal Articles

Palmitoylation of Tspan4 is essential for migrasome formation

Shuonan Wang, Weisi Wang, Jiamei Qiao, Sadiq Ali, Zheng Jiang, Dong Jiang, Junjie Ma, Yuwei Huang

J Cell Biol (2026) 225 (6): e202507023.

https://doi.org/10.1083/jcb.202507023

Published: 15 April 2026

View article titled, Palmitoylation of Tspan4 is essential for migrasome formation

Includes: Supplementary data

Journal Articles

ER-derived caveolin-coated vesicles transport newly synthesized cholesterol to the plasma membrane

Ming Sun, Yuan-Bin Liu, Pu-Yu Sun, Zhao-Chen Sheng, Jia-Wen Liu, Pei-Xin Yuan, Wen-Zhuo Zhu, Gang Deng, Xing-Yan Wen, Xiaolu Zhao, Jie Luo, Bao-Liang Song

J Cell Biol (2026) 225 (6): e202502001.

https://doi.org/10.1083/jcb.202502001

Published: 13 April 2026

View article titled, ER-derived caveolin-coated vesicles transport newly synthesized cholesterol to the plasma membrane

Includes: Supplementary data

Journal Articles

The SWR1 complex prevents the vacuolar delivery of ATG proteins through a noncanonical pathway

Siyu Fan, Huan Yang, Jianting Lei, Xinyue Gong, Yiyu Lin, Yuan Zhou, Yuhang Cui, Yuanyuan Ding, Mingzhu Fan, Shan Feng, Weijing Yao, Dong Fang, Kunrong Mei, Hongguang Xia, Cong Yi

J Cell Biol (2026) 225 (6): e202511133.

https://doi.org/10.1083/jcb.202511133

Published: 09 April 2026

View article titled, The SWR1 complex prevents the vacuolar delivery of ATG proteins through a noncanonical pathway

Includes: Supplementary data

Journal Articles

The KIF3B/B/KAP3 tail domain specifically facilitates TRIM46 transport to the axon initial segment

Xuguang Jiang, Sotaro Ichinose, Tadayuki Ogawa, Kento Yonezawa, Nobutaka Shimizu, Nobutaka Hirokawa

J Cell Biol (2026) 225 (5): e202503138.

https://doi.org/10.1083/jcb.202503138

Published: 30 March 2026

View article titled, The KIF3B/B/KAP3 tail domain specifically facilitates TRIM46 transport to the axon initial segment

Includes: Supplementary data

Journal Articles

How strong is a mitochondrial targeting signal?

Carlotta Peselj, F.-Nora Vögtle

J Cell Biol (2026) 225 (4): e202603036.

https://doi.org/10.1083/jcb.202603036

Published: 24 March 2026

View article titled, How strong is a mitochondrial targeting signal?

Journal Articles

A PTPN23-dependent ESCRT pathway is essential for constitutive secretion in mammalian cells

Danièle Stalder, Conceição Pereira, Dick J.H. van den Boomen, Petia Adarska, Dilip Menon, Daniel J. Fazakerley, Francesca Bottanelli, Paul J. Lehner, David C. Gershlick

J Cell Biol (2026) 225 (5): e202506111.

https://doi.org/10.1083/jcb.202506111

Published: 18 March 2026

View article titled, A PTPN23-dependent ESCRT pathway is essential for constitutive secretion in mammalian cells

Includes: Supplementary data

Journal Articles

Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy

Valeriya Gyurkovska, Rakhilya Murtazina, Sarah F. Zhao, Christopher B. Huppenbauer, Vadim Gaponenko, Nava Segev

J Cell Biol (2026) 225 (5): e202507166.

https://doi.org/10.1083/jcb.202507166

Published: 09 March 2026

View article titled, Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy

Includes: Supplementary data

Journal Articles

Hoi1 targets BLTP2 to ER–PM contact sites to regulate lipid homeostasis

Samantha K. Dziurdzik, Vaishnavi Sridhar, Hailey Eng, Sarah D. Neuman, Junran Yan, Michael Davey, Stefan Taubert, Arash Bashirullah, Elizabeth Conibear

J Cell Biol (2026) 225 (5): e202502131.

https://doi.org/10.1083/jcb.202502131

Published: 26 February 2026

View article titled, Hoi1 targets BLTP2 to ER–PM contact sites to regulate lipid homeostasis

Includes: Supplementary data

Journal Articles

Cullin-3 adaptor SHKBP1 inhibits SQSTM1/p62 oligomerization and Keap1 sequestration

Lin Luan, Xiaofu Cao, Zijun Xia, Shivanshi Vaid, Manuel D. Leonetti, Jeremy M. Baskin

J Cell Biol (2026) 225 (4): e202501207.

https://doi.org/10.1083/jcb.202501207

Published: 06 February 2026

View article titled, Cullin-3 adaptor SHKBP1 inhibits SQSTM1/p62 oligomerization and Keap1 sequestration

Includes: Supplementary data

Journal Articles

GRIPAP1 is an endosomal tethering factor mediating platelet α-granule biogenesis

Andrea L. Ambrosio, Hallie P. Febvre, Gabrielle H. Schusler, Santiago M. Di Pietro

J Cell Biol (2026) 225 (4): e202507149.

https://doi.org/10.1083/jcb.202507149

Published: 03 February 2026

View article titled, GRIPAP1 is an endosomal tethering factor mediating platelet α-granule biogenesis

Includes: Supplementary data

Journal Articles

Cholesterol depletion activates trafficking-coupled sphingolipid synthesis

Yeongho Kim, Jan Parolek, Christopher G. Burd

J Cell Biol (2026) 225 (4): e202502083.

https://doi.org/10.1083/jcb.202502083

Published: 20 January 2026

View article titled, Cholesterol depletion activates trafficking-coupled sphingolipid synthesis

Includes: Supplementary data

Journal Articles

Condensin II collaborates with cohesin to establish and maintain interphase chromosome territories

Takao Ono, Masatoshi Takagi, Hideyuki Tanabe, Tomoko Fujita, Noriko Saitoh, Akatsuki Kimura, Tatsuya Hirano

J Cell Biol (2026) 225 (4): e202511114.

https://doi.org/10.1083/jcb.202511114

Published: 09 January 2026

View article titled, Condensin II collaborates with cohesin to establish and maintain interphase chromosome territories

Includes: Supplementary data

Journal Articles

Mitochondrial presequences harbor variable strengths to maintain organellar function

Youmian Yan, Baigalmaa Erdenepurev, Thiago N. Menezes, Ian Collinson, Natalie M. Niemi

J Cell Biol (2026) 225 (4): e202507116.

https://doi.org/10.1083/jcb.202507116

Published: 08 January 2026

View article titled, Mitochondrial presequences harbor variable strengths to maintain organellar function

Includes: Supplementary data

Journal Articles

Regulation of the formin INF2 by actin monomers and calcium/calmodulin

Miriam Lee, Aiman Jalmukhambetova, T. Emme Burgin, Henry N. Higgs

J Cell Biol (2026) 225 (2): e202507147.

https://doi.org/10.1083/jcb.202507147

Published: 07 January 2026

View article titled, Regulation of the formin INF2 by actin monomers and calcium/calmodulin

Includes: Supplementary data

Journal Articles

The cell biologist’s guide to detecting and modulating membrane phospholipids

In Special Collection:

Reproducibility and Best Practices in Cell Biology

Michael Worcester, Morgan M.C. Ricci, Claire C. Weckerly, Jesus G. Calixto, Gerald R.V. Hammond

J Cell Biol (2026) 225 (2): e202508058.

https://doi.org/10.1083/jcb.202508058

Published: 02 January 2026

View article titled, The cell biologist’s guide to detecting and modulating membrane phospholipids

Journal Articles

CRM1 inhibits NPAT condensation and histone locus body formation via a competitive occupation strategy

Xiao Xia Cong, Shui Bo Xu, Wen Kai Zou, Xiu Kui Gao, Zhao Yuan Pan, Hao Di Liang, Juan Chen, Jia Li Tao, Xu Qi Chen, Rui Jie Chen, Bai Te Ge, Jia Hui Weng, Man Huang, Lin Rong Lu, Xiaohui Zou, Yi Ting Zhou, Li Ling Zheng

J Cell Biol (2026) 225 (2): e202412173.

https://doi.org/10.1083/jcb.202412173

Published: 02 January 2026

View article titled, CRM1 inhibits NPAT condensation and histone locus body formation via a competitive occupation strategy

Includes: Supplementary data

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Mitochondrially tethered Mmm1 can function as a sole lipid transporter at ER–mitochondria contacts

NASP functions in the cytoplasm to prevent histone H3 aggregation during early embryogenesis

Time-resolved tmFRET reveals GTP-coupled conformational changes in Mfn1

Divergent Rickettsia species exhibit distinct mechanisms of actin-based motility

Palmitoylation of Tspan4 is essential for migrasome formation

ER-derived caveolin-coated vesicles transport newly synthesized cholesterol to the plasma membrane

The SWR1 complex prevents the vacuolar delivery of ATG proteins through a noncanonical pathway

The KIF3B/B/KAP3 tail domain specifically facilitates TRIM46 transport to the axon initial segment

How strong is a mitochondrial targeting signal?

A PTPN23-dependent ESCRT pathway is essential for constitutive secretion in mammalian cells

Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy

Hoi1 targets BLTP2 to ER–PM contact sites to regulate lipid homeostasis

Cullin-3 adaptor SHKBP1 inhibits SQSTM1/p62 oligomerization and Keap1 sequestration

GRIPAP1 is an endosomal tethering factor mediating platelet α-granule biogenesis

Cholesterol depletion activates trafficking-coupled sphingolipid synthesis

Condensin II collaborates with cohesin to establish and maintain interphase chromosome territories

Mitochondrial presequences harbor variable strengths to maintain organellar function

Regulation of the formin INF2 by actin monomers and calcium/calmodulin

The cell biologist’s guide to detecting and modulating membrane phospholipids

CRM1 inhibits NPAT condensation and histone locus body formation via a competitive occupation strategy

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