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Journal Articles

How strong is a mitochondrial targeting signal?

Carlotta Peselj, F.-Nora Vögtle

J Cell Biol (2026) 225 (4): e202603036.

https://doi.org/10.1083/jcb.202603036

Published: 24 March 2026

View article titled, How strong is a mitochondrial targeting signal?

Journal Articles

A PTPN23-dependent ESCRT pathway is essential for constitutive secretion in mammalian cells

Danièle Stalder, Conceição Pereira, Dick J.H. van den Boomen, Petia Adarska, Dilip Menon, Daniel J. Fazakerley, Francesca Bottanelli, Paul J. Lehner, David C. Gershlick

J Cell Biol (2026) 225 (5): e202506111.

https://doi.org/10.1083/jcb.202506111

Published: 18 March 2026

View article titled, A PTPN23-dependent ESCRT pathway is essential for constitutive secretion in mammalian cells

Includes: Supplementary data

Journal Articles

Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy

Valeriya Gyurkovska, Rakhilya Murtazina, Sarah F. Zhao, Christopher B. Huppenbauer, Vadim Gaponenko, Nava Segev

J Cell Biol (2026) 225 (5): e202507166.

https://doi.org/10.1083/jcb.202507166

Published: 09 March 2026

View article titled, Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy

Includes: Supplementary data

Journal Articles

Hoi1 targets BLTP2 to ER–PM contact sites to regulate lipid homeostasis

Samantha K. Dziurdzik, Vaishnavi Sridhar, Hailey Eng, Sarah D. Neuman, Junran Yan, Michael Davey, Stefan Taubert, Arash Bashirullah, Elizabeth Conibear

J Cell Biol (2026) 225 (5): e202502131.

https://doi.org/10.1083/jcb.202502131

Published: 26 February 2026

View article titled, Hoi1 targets BLTP2 to ER–PM contact sites to regulate lipid homeostasis

Includes: Supplementary data

Journal Articles

Cullin-3 adaptor SHKBP1 inhibits SQSTM1/p62 oligomerization and Keap1 sequestration

Lin Luan, Xiaofu Cao, Zijun Xia, Shivanshi Vaid, Manuel D. Leonetti, Jeremy M. Baskin

J Cell Biol (2026) 225 (4): e202501207.

https://doi.org/10.1083/jcb.202501207

Published: 06 February 2026

View article titled, Cullin-3 adaptor SHKBP1 inhibits SQSTM1/p62 oligomerization and Keap1 sequestration

Includes: Supplementary data

Journal Articles

GRIPAP1 is an endosomal tethering factor mediating platelet α-granule biogenesis

Andrea L. Ambrosio, Hallie P. Febvre, Gabrielle H. Schusler, Santiago M. Di Pietro

J Cell Biol (2026) 225 (4): e202507149.

https://doi.org/10.1083/jcb.202507149

Published: 03 February 2026

View article titled, GRIPAP1 is an endosomal tethering factor mediating platelet α-granule biogenesis

Includes: Supplementary data

Journal Articles

Cholesterol depletion activates trafficking-coupled sphingolipid synthesis

Yeongho Kim, Jan Parolek, Christopher G. Burd

J Cell Biol (2026) 225 (4): e202502083.

https://doi.org/10.1083/jcb.202502083

Published: 20 January 2026

View article titled, Cholesterol depletion activates trafficking-coupled sphingolipid synthesis

Includes: Supplementary data

Journal Articles

Condensin II collaborates with cohesin to establish and maintain interphase chromosome territories

Takao Ono, Masatoshi Takagi, Hideyuki Tanabe, Tomoko Fujita, Noriko Saitoh, Akatsuki Kimura, Tatsuya Hirano

J Cell Biol (2026) 225 (4): e202511114.

https://doi.org/10.1083/jcb.202511114

Published: 09 January 2026

View article titled, Condensin II collaborates with cohesin to establish and maintain interphase chromosome territories

Includes: Supplementary data

Journal Articles

Mitochondrial presequences harbor variable strengths to maintain organellar function

Youmian Yan, Baigalmaa Erdenepurev, Thiago N. Menezes, Ian Collinson, Natalie M. Niemi

J Cell Biol (2026) 225 (4): e202507116.

https://doi.org/10.1083/jcb.202507116

Published: 08 January 2026

View article titled, Mitochondrial presequences harbor variable strengths to maintain organellar function

Includes: Supplementary data

Journal Articles

Regulation of the formin INF2 by actin monomers and calcium/calmodulin

Miriam Lee, Aiman Jalmukhambetova, T. Emme Burgin, Henry N. Higgs

J Cell Biol (2026) 225 (2): e202507147.

https://doi.org/10.1083/jcb.202507147

Published: 07 January 2026

View article titled, Regulation of the formin INF2 by actin monomers and calcium/calmodulin

Includes: Supplementary data

Journal Articles

CRM1 inhibits NPAT condensation and histone locus body formation via a competitive occupation strategy

Xiao Xia Cong, Shui Bo Xu, Wen Kai Zou, Xiu Kui Gao, Zhao Yuan Pan, Hao Di Liang, Juan Chen, Jia Li Tao, Xu Qi Chen, Rui Jie Chen, Bai Te Ge, Jia Hui Weng, Man Huang, Lin Rong Lu, Xiaohui Zou, Yi Ting Zhou, Li Ling Zheng

J Cell Biol (2026) 225 (2): e202412173.

https://doi.org/10.1083/jcb.202412173

Published: 02 January 2026

View article titled, CRM1 inhibits NPAT condensation and histone locus body formation via a competitive occupation strategy

Includes: Supplementary data

Journal Articles

The cell biologist’s guide to detecting and modulating membrane phospholipids

In Special Collection:

Reproducibility and Best Practices in Cell Biology

Michael Worcester, Morgan M.C. Ricci, Claire C. Weckerly, Jesus G. Calixto, Gerald R.V. Hammond

J Cell Biol (2026) 225 (2): e202508058.

https://doi.org/10.1083/jcb.202508058

Published: 02 January 2026

View article titled, The cell biologist’s guide to detecting and modulating membrane phospholipids

Journal Articles

p62 sorts Lupus La and selected microRNAs into breast cancer-derived exosomes

Jordan Matthew Ngo, Justin Krish Williams, Morayma Mercedes Temoche-Diaz, Abinayaa Murugupandiyan, Randy Schekman

J Cell Biol (2025) 225 (3): e202503087.

https://doi.org/10.1083/jcb.202503087

Published: 26 December 2025

View article titled, p62 sorts Lupus La and selected microRNAs into breast cancer-derived exosomes

Includes: Supplementary data

Journal Articles

Ist2 is a phospholipid scramblase that links lipid transport at the ER to organelle homeostasis

Heitor Gobbi Sebinelli, Camille Syska, Hafez Razmazma, Véronique Albanèse, Ana Rita Dias Araujo, Cecile Hilpert, Cédric Montigny, Christine Jaxel, Manuella Tchamba, Karolina Belingar, Juan Martín D’Ambrosio, Luca Monticelli, Guillaume Lenoir, Alenka Čopič

J Cell Biol (2025) 225 (2): e202502112.

https://doi.org/10.1083/jcb.202502112

Published: 26 December 2025

View article titled, Ist2 is a phospholipid scramblase that links lipid transport at the ER to organelle homeostasis

Includes: Supplementary data

Journal Articles

TMEDs mediate versatile cargo transport in vesicle-dependent unconventional secretion

Jianfei Zheng, Haodong Wang, Yuxin Sun, Pei Chang, Xing Deng, Lijingyao Zhang, Lin Zhu, Kangling Zhu, Dong Peng, Haiteng Deng, Min Zhang, Liang Ge

J Cell Biol (2025) 225 (1): e202503075.

https://doi.org/10.1083/jcb.202503075

Published: 09 December 2025

View article titled, TMEDs mediate versatile cargo transport in vesicle-dependent unconventional secretion

Includes: Supplementary data

Journal Articles

Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles

Dorival Mendes Rodrigues-Junior, Ana Rosa Sáez-Ibáñez, Takeshi Terabayashi, Nina Daubel, Taija Mäkinen, Olof Idevall-Hagren, Aristidis Moustakas, Ingvar Ferby

J Cell Biol (2025) 225 (1): e202501255.

https://doi.org/10.1083/jcb.202501255

Published: 05 December 2025

View article titled, Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles

Journal Articles

lncRNA EGFR-AS1 promotes DNA damage repair by enhancing PARP1-mediated PARylation

Kun Gao, Ruiya Shi, Chenying Xu, Zhaoyang Mao, Changying Guo, Liang Jin

J Cell Biol (2025) 225 (1): e202501091.

https://doi.org/10.1083/jcb.202501091

Published: 03 December 2025

View article titled, lncRNA EGFR-AS1 promotes DNA damage repair by enhancing PARP1-mediated PARylation

Includes: Supplementary data

Journal Articles

Talin–tensin3 interactions regulate fibrillar adhesion formation and tensin3 phase separation

Xingchen Li, Rafaella Konstantinou, Vinod Kumar Meena, Saba Notash, Komal Khalil, Tom Whalley, Paul Atherton, Igor Barsukov, Thomas Zacharchenko, Christoph Ballestrem

J Cell Biol (2025) 225 (1): e202503155.

https://doi.org/10.1083/jcb.202503155

Published: 21 November 2025

View article titled, Talin–tensin3 interactions regulate fibrillar adhesion formation and tensin3 phase separation

Includes: Supplementary data

Journal Articles

Intramolecular regulation of the MT-severing enzyme Katanin prevents futile ATP hydrolysis

Nicolas Joly, Lionel Pintard

J Cell Biol (2025) 225 (2): e202506192.

https://doi.org/10.1083/jcb.202506192

Published: 19 November 2025

View article titled, Intramolecular regulation of the MT-severing enzyme Katanin prevents futile ATP hydrolysis

Includes: Supplementary data

Journal Articles

Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation

Clyde Savio Pinto, Saskia E. Bakker, Andrejus Suchenko, Isabella M. Kolodny, Hamdi Hussain, Tomoyuki Hatano, Karuna Sampath, Krishna Chinthalapudi, Sarah M. Heissler, Masanori Mishima, Mohan Balasubramanian

J Cell Biol (2025) 225 (1): e202409067.

https://doi.org/10.1083/jcb.202409067

Published: 14 November 2025

View article titled, Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation

Includes: Supplementary data

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How strong is a mitochondrial targeting signal?

A PTPN23-dependent ESCRT pathway is essential for constitutive secretion in mammalian cells

Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy

Hoi1 targets BLTP2 to ER–PM contact sites to regulate lipid homeostasis

Cullin-3 adaptor SHKBP1 inhibits SQSTM1/p62 oligomerization and Keap1 sequestration

GRIPAP1 is an endosomal tethering factor mediating platelet α-granule biogenesis

Cholesterol depletion activates trafficking-coupled sphingolipid synthesis

Condensin II collaborates with cohesin to establish and maintain interphase chromosome territories

Mitochondrial presequences harbor variable strengths to maintain organellar function

Regulation of the formin INF2 by actin monomers and calcium/calmodulin

CRM1 inhibits NPAT condensation and histone locus body formation via a competitive occupation strategy

The cell biologist’s guide to detecting and modulating membrane phospholipids

p62 sorts Lupus La and selected microRNAs into breast cancer-derived exosomes

Ist2 is a phospholipid scramblase that links lipid transport at the ER to organelle homeostasis

TMEDs mediate versatile cargo transport in vesicle-dependent unconventional secretion

Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles

lncRNA EGFR-AS1 promotes DNA damage repair by enhancing PARP1-mediated PARylation

Talin–tensin3 interactions regulate fibrillar adhesion formation and tensin3 phase separation

Intramolecular regulation of the MT-severing enzyme Katanin prevents futile ATP hydrolysis

Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation

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