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Journal Articles

The calcium-binding protein S100A1 binds to titin’s N2A insertion sequence in a pH-dependent manner

Sabrina I. Apel, Emily Schaffter, Nicholas Melisi, Matthew J. Gage

J Gen Physiol (2024) 157 (1): e202313472.

https://doi.org/10.1085/jgp.202313472

Published: 31 December 2024

View article titled, The calcium-binding protein S100A1 binds to titin’s N2A insertion sequence in a pH-dependent manner

Includes: Supplementary data

Journal Articles

Isoform-specific N-linked glycosylation of Na_V channel α-subunits alters β-subunit binding sites

Christopher A. Beaudoin, Manas Kohli, Samantha C. Salvage, Hengrui Liu, Samuel J. Arundel, Samir W. Hamaia, Ming Lei, Christopher L.-H. Huang, Antony P. Jackson

J Gen Physiol (2024) 157 (1): e202413609.

https://doi.org/10.1085/jgp.202413609

Published: 16 December 2024

View article titled, Isoform-specific N-linked glycosylation of NaV channel α-subunits alters β-subunit binding sites

Journal Articles

Structure and selectivity of a glutamate-specific TAXI TRAP binding protein from Vibrio cholerae

Joseph F.S. Davies, Andrew Daab, Nicholas Massouh, Corey Kirkland, Bernadette Strongitharm, Andrew Leech, Marta Farré, Gavin H. Thomas, Christopher Mulligan

J Gen Physiol (2024) 156 (12): e202413584.

https://doi.org/10.1085/jgp.202413584

Published: 18 November 2024

View article titled, Structure and selectivity of a glutamate-specific TAXI TRAP binding protein from Vibrio cholerae

Includes: Supplementary data

Journal Articles

The artificial intelligence revolution...in unethical publishing: Will AI worsen our dysfunctional publishing system?

Thiago F. A. França, José Maria Monserrat

J Gen Physiol (2024) 156 (11): e202413654.

https://doi.org/10.1085/jgp.202413654

Published: 07 October 2024

View article titled, The artificial intelligence revolution...in unethical publishing: Will AI worsen our dysfunctional publishing system?

Journal Articles

Fluorescence labeling strategies for cell surface expression of TRPV1

Taylor M. Mott, Grace C. Wulffraat, Alex J. Eddins, Ryan A. Mehl, Eric N. Senning

J Gen Physiol (2024) 156 (10): e202313523.

https://doi.org/10.1085/jgp.202313523

Published: 20 August 2024

View article titled, Fluorescence labeling strategies for cell surface expression of TRPV1

Includes: Supplementary data

Journal Articles

Transport of metformin metabolites by guanidinium exporters of the small multidrug resistance family

In Special Collection:

Molecular Insights into Membrane Protein Function

Rachael M. Lucero, Kemal Demirer, Trevor Justin Yeh, Randy B. Stockbridge

J Gen Physiol (2024) 156 (3): e202313464.

https://doi.org/10.1085/jgp.202313464

Published: 31 January 2024

View article titled, Transport of metformin metabolites by guanidinium exporters of the small multidrug resistance family

Includes: Supplementary data

Journal Articles

Blood flow-bearing physical forces, endothelial glycocalyx, and liver enzyme mobilization: A hypothesis

Lorena Carmina Hernández-Espinosa, Rolando Hernández-Muñoz

J Gen Physiol (2024) 156 (3): e202313462.

https://doi.org/10.1085/jgp.202313462

Published: 17 January 2024

View article titled, Blood flow-bearing physical forces, endothelial glycocalyx, and liver enzyme mobilization: A hypothesis

Journal Articles

Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel Na_V1.7

In Special Collection:

Biophysics 2024 , Neuroscience Collection 2024

Goragot Wisedchaisri, Tamer M. Gamal El-Din, Natasha M. Powell, Ning Zheng, William A. Catterall

J Gen Physiol (2023) 155 (12): e202313450.

https://doi.org/10.1085/jgp.202313450

Published: 30 October 2023

View article titled, Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7

Includes: Supplementary data

Journal Articles

Mitochondrial morphology governs ATP production rate

Guadalupe C. Garcia, Kavya Gupta, Thomas M. Bartol, Terrence J. Sejnowski, Padmini Rangamani

J Gen Physiol (2023) 155 (9): e202213263.

https://doi.org/10.1085/jgp.202213263

Published: 24 August 2023

View article titled, Mitochondrial morphology governs ATP production rate

Journal Articles

Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption

J Gen Physiol (2023) 155 (7): e202213268.

https://doi.org/10.1085/jgp.202213268

Published: 25 May 2023

View article titled, Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption

Includes: Supplementary data

Journal Articles

Binding motif for RIC-3 chaperon protein in serotonin type 3A receptors

Hoa Quynh Do, Michaela Jansen

J Gen Physiol (2023) 155 (6): e202213305.

https://doi.org/10.1085/jgp.202213305

Published: 07 April 2023

View article titled, Binding motif for RIC-3 chaperon protein in serotonin type 3A receptors

Includes: Supplementary data

Journal Articles

Optimization of CFTR gating through the evolution of its extracellular loops

In Special Collection:

Biophysics 2024 , Molecular Insights into Membrane Protein Function

Márton A. Simon, László Csanády

J Gen Physiol (2023) 155 (4): e202213264.

https://doi.org/10.1085/jgp.202213264

Published: 01 February 2023

View article titled, Optimization of CFTR gating through the evolution of its extracellular loops

Journal Articles

Dual regulation of Kv7.2/7.3 channels by long-chain n-alcohols

Da-Jeong Jeong, Kwon-Woo Kim, Byung-Chang Suh

J Gen Physiol (2022) 155 (2): e202213191.

https://doi.org/10.1085/jgp.202213191

Published: 19 December 2022

View article titled, Dual regulation of Kv7.2/7.3 channels by long-chain n-alcohols

Journal Articles

Mechanistic insights on K_ATP channel regulation from cryo-EM structures

Camden M. Driggers, Show-Ling Shyng

J Gen Physiol (2022) 155 (1): e202113046.

https://doi.org/10.1085/jgp.202113046

Published: 28 November 2022

View article titled, Mechanistic insights on KATP channel regulation from cryo-EM structures

Journal Articles

Full opening of helix bundle crossing does not lead to NaK channel activation

In Special Collection:

Biophysics 2023

Vilius Kurauskas, Marco Tonelli, Katherine Henzler-Wildman

J Gen Physiol (2022) 154 (12): e202213196.

https://doi.org/10.1085/jgp.202213196

Published: 03 November 2022

View article titled, Full opening of helix bundle crossing does not lead to NaK channel activation

Includes: Supplementary data

Journal Articles

Role of a conserved ion-binding site tyrosine in ion selectivity of the Na⁺/K⁺ pump

Kerri Spontarelli, Daniel T. Infield, Hang N. Nielsen, Rikke Holm, Victoria C. Young, Jason D. Galpin, Christopher A. Ahern, Bente Vilsen, Pablo Artigas

J Gen Physiol (2022) 154 (7): e202113039.

https://doi.org/10.1085/jgp.202113039

Published: 03 June 2022

View article titled, Role of a conserved ion-binding site tyrosine in ion selectivity of the Na+/K+ pump

Journal Articles

Burmese pythons exhibit a transient adaptation to nutrient overload that prevents liver damage

Jason A. Magida, Yuxiao Tan, Christopher E. Wall, Brooke C. Harrison, Thomas G. Marr, Angela K. Peter, Cecilia A. Riquelme, Leslie A. Leinwand

J Gen Physiol (2022) 154 (4): e202113008.

https://doi.org/10.1085/jgp.202113008

Published: 24 March 2022

View article titled, Burmese pythons exhibit a transient adaptation to nutrient overload that prevents liver damage

Includes: Supplementary data

Journal Articles

Cooperative binding ensures the obligatory melibiose/Na⁺ cotransport in MelB

Parameswaran Hariharan, Lan Guan

J Gen Physiol (2021) 153 (8): e202012710.

https://doi.org/10.1085/jgp.202012710

Published: 10 June 2021

View article titled, Cooperative binding ensures the obligatory melibiose/Na+ cotransport in MelB

Journal Articles

Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate

In Special Collection:

Biophysics 2022 , Neuroscience Collection 2021

Peter Proks, Marcus Schewe, Linus J. Conrad, Shanlin Rao, Kristin Rathje, Karin E.J. Rödström, Elisabeth P. Carpenter, Thomas Baukrowitz, Stephen J. Tucker

J Gen Physiol (2021) 153 (8): e202012812.

https://doi.org/10.1085/jgp.202012812

Published: 25 May 2021

View article titled, Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate

Includes: Supplementary data

Journal Articles

Cardiomyopathic mutations in essential light chain reveal mechanisms regulating the super relaxed state of myosin

Yoel H. Sitbon, Francisca Diaz, Katarzyna Kazmierczak, Jingsheng Liang, Medhi Wangpaichitr, Danuta Szczesna-Cordary

J Gen Physiol (2021) 153 (7): e202012801.

https://doi.org/10.1085/jgp.202012801

Published: 20 May 2021

View article titled, Cardiomyopathic mutations in essential light chain reveal mechanisms regulating the super relaxed state of myosin

Includes: Supplementary data

NARROW

The calcium-binding protein S100A1 binds to titin’s N2A insertion sequence in a pH-dependent manner

Isoform-specific N-linked glycosylation of Na_V channel α-subunits alters β-subunit binding sites

Structure and selectivity of a glutamate-specific TAXI TRAP binding protein from Vibrio cholerae

The artificial intelligence revolution...in unethical publishing: Will AI worsen our dysfunctional publishing system?

Fluorescence labeling strategies for cell surface expression of TRPV1

Transport of metformin metabolites by guanidinium exporters of the small multidrug resistance family

Blood flow-bearing physical forces, endothelial glycocalyx, and liver enzyme mobilization: A hypothesis

Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel Na_V1.7

Mitochondrial morphology governs ATP production rate

Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption

Binding motif for RIC-3 chaperon protein in serotonin type 3A receptors

Optimization of CFTR gating through the evolution of its extracellular loops

Dual regulation of Kv7.2/7.3 channels by long-chain n-alcohols

Mechanistic insights on K_ATP channel regulation from cryo-EM structures

Full opening of helix bundle crossing does not lead to NaK channel activation

Role of a conserved ion-binding site tyrosine in ion selectivity of the Na⁺/K⁺ pump

Burmese pythons exhibit a transient adaptation to nutrient overload that prevents liver damage

Cooperative binding ensures the obligatory melibiose/Na⁺ cotransport in MelB

Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate

Cardiomyopathic mutations in essential light chain reveal mechanisms regulating the super relaxed state of myosin

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