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Michael A. Geeves
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Journal Articles

Myosin’s powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin

Michael J. Rynkiewicz, Matthew C. Childers, Olga E. Karpicheva, Michael Regnier, Michael A. Geeves, William Lehman
Journal: Journal of General Physiology
J Gen Physiol (2024) 156 (5): e202413538.
https://doi.org/10.1085/jgp.202413538
Published: 12 April 2024
View article titled, Myosin’s powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin
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Includes: Supplementary data
Journal Articles

Single-molecule imaging reveals how mavacamten and PKA modulate ATP turnover in skeletal muscle myofibrils

Matvey Pilagov, Laurens W.H.J. Heling, Jonathan Walklate, Michael A. Geeves, Neil M. Kad
Journal: Journal of General Physiology
J Gen Physiol (2022) 155 (1): e202213087.
https://doi.org/10.1085/jgp.202213087
Published: 17 November 2022
View article titled, Single-molecule imaging reveals how mavacamten and PKA modulate ATP turnover in skeletal muscle myofibrils
Open the PDF for Single-molecule imaging reveals how mavacamten and PKA modulate ATP turnover in skeletal muscle myofibrils in another window
Includes: Supplementary data
Journal Articles

Multiscale modeling of twitch contractions in cardiac trabeculae

Srboljub M. Mijailovich, Momcilo Prodanovic, Corrado Poggesi, Michael A. Geeves, Michael Regnier
Journal: Journal of General Physiology
J Gen Physiol (2021) 153 (3): e202012604.
https://doi.org/10.1085/jgp.202012604
Published: 29 January 2021
View article titled, Multiscale modeling of twitch contractions in cardiac trabeculae
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Includes: Supplementary data
Journal Articles

The mechanism of thin filament regulation: Models in conflict?

Michael A. Geeves, Sherwin S. Lehrer, William Lehman
Journal: Journal of General Physiology
J Gen Physiol (2019) 151 (11): 1265–1271.
https://doi.org/10.1085/jgp.201912446
Published: 30 September 2019
View article titled, The mechanism of thin filament regulation: Models in conflict?
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Journal Articles

Nebulin and titin modulate cross-bridge cycling and length-dependent calcium sensitivity

Srboljub M. Mijailovich, Boban Stojanovic, Djordje Nedic, Marina Svicevic, Michael A. Geeves, Thomas C. Irving, Henk L. Granzier
Journal: Journal of General Physiology
J Gen Physiol (2019) 151 (5): 680–704.
https://doi.org/10.1085/jgp.201812165
Published: 04 April 2019
View article titled, Nebulin and titin modulate cross-bridge cycling and length-dependent calcium sensitivity
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Includes: Supplementary data
Journal Articles

Three-dimensional stochastic model of actin–myosin binding in the sarcomere lattice

Srboljub M. Mijailovich, Oliver Kayser-Herold, Boban Stojanovic, Djordje Nedic, Thomas C. Irving, Michael A. Geeves
Journal: Journal of General Physiology
J Gen Physiol (2016) 148 (6): 459–488.
https://doi.org/10.1085/jgp.201611608
Published: 18 November 2016
View article titled, Three-dimensional stochastic model of actin–myosin binding in the sarcomere lattice
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Includes: Supplementary data