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Novel Ca²⁺ wave mechanisms in cardiac myocytes revealed by multiscale Ca²⁺ release model

Morris Vysma, James S. Welsh, Derek R. Laver

J Gen Physiol (2025) 157 (3): e202413543.

https://doi.org/10.1085/jgp.202413543

Published: 06 March 2025

View articletitled, Novel Ca2+ wave mechanisms in cardiac myocytes revealed by multiscale Ca2+ release model

Includes: Supplementary data

Journal Articles

Dantrolene inhibition of ryanodine channels (RyR2) in artificial lipid bilayers depends on FKBP12.6

Kafa Walweel, Nicole Beard, Dirk F. van Helden, Derek R. Laver

J Gen Physiol (2023) 155 (8): e202213277.

https://doi.org/10.1085/jgp.202213277

Published: 06 June 2023

View articletitled, Dantrolene inhibition of ryanodine channels (RyR2) in artificial lipid bilayers depends on FKBP12.6

Includes: Supplementary data

Journal Articles

Differences in the regulation of RyR2 from human, sheep, and rat by Ca²⁺ and Mg²⁺ in the cytoplasm and in the lumen of the sarcoplasmic reticulum

Kafa Walweel, Jiao Li, Peter Molenaar, Mohammad S. Imtiaz, Anthony Quail, Cris G. dos Remedios, Nicole A. Beard, Angela F. Dulhunty, Dirk F. van Helden, Derek R. Laver

J Gen Physiol (2014) 144 (3): 263–271.

https://doi.org/10.1085/jgp.201311157

Published: 25 August 2014

View articletitled, Differences in the regulation of RyR2 from human, sheep, and rat by Ca2+ and Mg2+ in the cytoplasm and in the lumen of the sarcoplasmic reticulum

Journal Articles

Luminal Mg²⁺, A Key Factor Controlling RYR2-mediated Ca²⁺ Release: Cytoplasmic and Luminal Regulation Modeled in a Tetrameric Channel

Derek R. Laver, Bonny N. Honen

J Gen Physiol (2008) 132 (4): 429–446.

https://doi.org/10.1085/jgp.200810001

Published: 29 September 2008

View articletitled, Luminal Mg2+, A Key Factor Controlling RYR2-mediated Ca2+ Release: Cytoplasmic and Luminal Regulation Modeled in a Tetrameric Channel

Journal Articles

Luminal Ca²⁺–regulated Mg²⁺ Inhibition of Skeletal RyRs Reconstituted as Isolated Channels or Coupled Clusters

Derek R. Laver, Erin R. O'Neill, Graham D. Lamb

J Gen Physiol (2004) 124 (6): 741–758.

https://doi.org/10.1085/jgp.200409092

Published: 15 November 2004

View articletitled, Luminal Ca2+–regulated Mg2+ Inhibition of Skeletal RyRs Reconstituted as Isolated Channels or Coupled Clusters

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Novel Ca²⁺ wave mechanisms in cardiac myocytes revealed by multiscale Ca²⁺ release model

Dantrolene inhibition of ryanodine channels (RyR2) in artificial lipid bilayers depends on FKBP12.6

Differences in the regulation of RyR2 from human, sheep, and rat by Ca²⁺ and Mg²⁺ in the cytoplasm and in the lumen of the sarcoplasmic reticulum

Luminal Mg²⁺, A Key Factor Controlling RYR2-mediated Ca²⁺ Release: Cytoplasmic and Luminal Regulation Modeled in a Tetrameric Channel

Luminal Ca²⁺–regulated Mg²⁺ Inhibition of Skeletal RyRs Reconstituted as Isolated Channels or Coupled Clusters

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Update search

Novel Ca2+ wave mechanisms in cardiac myocytes revealed by multiscale Ca2+ release model

Dantrolene inhibition of ryanodine channels (RyR2) in artificial lipid bilayers depends on FKBP12.6

Differences in the regulation of RyR2 from human, sheep, and rat by Ca2+ and Mg2+ in the cytoplasm and in the lumen of the sarcoplasmic reticulum

Luminal Mg2+, A Key Factor Controlling RYR2-mediated Ca2+ Release: Cytoplasmic and Luminal Regulation Modeled in a Tetrameric Channel

Luminal Ca2+–regulated Mg2+ Inhibition of Skeletal RyRs Reconstituted as Isolated Channels or Coupled Clusters

Email alerts

This Feature Is Available To Subscribers Only

Novel Ca²⁺ wave mechanisms in cardiac myocytes revealed by multiscale Ca²⁺ release model

Differences in the regulation of RyR2 from human, sheep, and rat by Ca²⁺ and Mg²⁺ in the cytoplasm and in the lumen of the sarcoplasmic reticulum

Luminal Mg²⁺, A Key Factor Controlling RYR2-mediated Ca²⁺ Release: Cytoplasmic and Luminal Regulation Modeled in a Tetrameric Channel

Luminal Ca²⁺–regulated Mg²⁺ Inhibition of Skeletal RyRs Reconstituted as Isolated Channels or Coupled Clusters