Issues

Cover picture: Gating energy changes at the acetylcholine receptor transmitter binding site were estimated from the kinetics of spontaneous currents. (Top) Left, unliganded Torpedo receptor; right, the α_εbinding site (right: yellow, loop A; green, loop B; purple, loop C; white, complementary subunit). (Bottom) Single-channel currents from unliganded receptors with the mutation αY190R. Each cluster of openings (down) is from one receptor (see article by Purohit and Auerbach, 321–331).