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James N. Weiss
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Journal Articles

Suppression of ventricular arrhythmias by targeting late L-type Ca2+ current

In Special Collection:
Ion Channels Update 2022
Marina Angelini, Arash Pezhouman, Nicoletta Savalli, Marvin G. Chang, Federica Steccanella, Kyle Scranton, Guillaume Calmettes, Michela Ottolia, Antonios Pantazis, Hrayr S. Karagueuzian, James N. Weiss, Riccardo Olcese
Journal: Journal of General Physiology
J Gen Physiol (2021) 153 (12): e202012584.
DOI: https://doi.org/10.1085/jgp.202012584
Published: 26 October 2021
View article titled, Suppression of ventricular arrhythmias by targeting late L-type Ca<sup>2+</sup> current
Click here to open pdf in another window PDF for Suppression of ventricular arrhythmias by targeting late L-type Ca<sup>2+</sup> current
Includes: Supplementary data
Journal Articles

The α2δ-1 subunit remodels CaV1.2 voltage sensors and allows Ca2+ influx at physiological membrane potentials

Nicoletta Savalli, Antonios Pantazis, Daniel Sigg, James N. Weiss, Alan Neely, Riccardo Olcese
Journal: Journal of General Physiology
J Gen Physiol (2016) 148 (2): 147–159.
DOI: https://doi.org/10.1085/jgp.201611586
Published: 01 August 2016
View article titled, The α<sub>2</sub>δ-1 subunit remodels Ca<sub>V</sub>1.2 voltage sensors and allows Ca<sup>2+</sup> influx at physiological membrane potentials
Click here to open pdf in another window PDF for The α<sub>2</sub>δ-1 subunit remodels Ca<sub>V</sub>1.2 voltage sensors and allows Ca<sup>2+</sup> influx at physiological membrane potentials
Includes: Supplementary data
Journal Articles

Targeting the late component of the cardiac L-type Ca2+ current to suppress early afterdepolarizations

Roshni V. Madhvani, Marina Angelini, Yuanfang Xie, Antonios Pantazis, Silvie Suriany, Nils P. Borgstrom, Alan Garfinkel, Zhilin Qu, James N. Weiss, Riccardo Olcese
Journal: Journal of General Physiology
J Gen Physiol (2015) 145 (5): 395–404.
DOI: https://doi.org/10.1085/jgp.201411288
Published: 27 April 2015
View article titled, Targeting the late component of the cardiac L-type Ca<sup>2+</sup> current to suppress early afterdepolarizations
Click here to open pdf in another window PDF for Targeting the late component of the cardiac L-type Ca<sup>2+</sup> current to suppress early afterdepolarizations
Includes: Multimedia, Supplementary data
Journal Articles

Hexokinase–mitochondrial interactions regulate glucose metabolism differentially in adult and neonatal cardiac myocytes

Guillaume Calmettes, Scott A. John, James N. Weiss, Bernard Ribalet
Journal: Journal of General Physiology
J Gen Physiol (2013) 142 (4): 425–436.
DOI: https://doi.org/10.1085/jgp.201310968
Published: 30 September 2013
View article titled, Hexokinase–mitochondrial interactions regulate glucose metabolism differentially in adult and neonatal cardiac myocytes
Click here to open pdf in another window PDF for Hexokinase–mitochondrial interactions regulate glucose metabolism differentially in adult and neonatal cardiac myocytes
Includes: Supplementary data
Journal Articles

Oscillations at odds in the heart

James N. Weiss, Jun-Hai Yang
Journal: Journal of General Physiology
J Gen Physiol (2010) 135 (4): 303–305.
DOI: https://doi.org/10.1085/jgp.201010422
Published: 15 March 2010
View article titled, Oscillations at odds in the heart
Click here to open pdf in another window PDF for Oscillations at odds in the heart
Journal Articles

Long Polyamines Act as Cofactors in PIP2 Activation of Inward Rectifier Potassium (Kir2.1) Channels

Lai-Hua Xie, Scott A. John, Bernard Ribalet, James N. Weiss
Journal: Journal of General Physiology
J Gen Physiol (2005) 126 (6): 541–549.
DOI: https://doi.org/10.1085/jgp.200509380
Published: 28 November 2005
View article titled, Long Polyamines Act as Cofactors in PIP<sub>2</sub> Activation of Inward Rectifier Potassium (Kir2.1) Channels
Click here to open pdf in another window PDF for Long Polyamines Act as Cofactors in PIP<sub>2</sub> Activation of Inward Rectifier Potassium (Kir2.1) Channels
Journal Articles

Mechanism of Inward Rectification in Kir Channels

Scott A. John, Lai-Hua Xie, James N. Weiss
Journal: Journal of General Physiology
J Gen Physiol (2004) 123 (5): 623–625.
DOI: https://doi.org/10.1085/jgp.200409017
Published: 12 April 2004
View article titled, Mechanism of Inward Rectification in Kir Channels
Click here to open pdf in another window PDF for Mechanism of Inward Rectification in Kir Channels
Journal Articles

Spermine Block of the Strong Inward Rectifier Potassium Channel Kir2.1 : Dual Roles of Surface Charge Screening and Pore Block

Lai-Hua Xie, Scott A. John, James N. Weiss
Journal: Journal of General Physiology
J Gen Physiol (2002) 120 (1): 53–66.
DOI: https://doi.org/10.1085/jgp.20028576
Published: 24 June 2002
View article titled, Spermine Block of the Strong Inward Rectifier Potassium Channel Kir2.1 : <span class="subtitle">Dual Roles of Surface Charge Screening and Pore Block </span>
Click here to open pdf in another window PDF for Spermine Block of the Strong Inward Rectifier Potassium Channel Kir2.1 : <span class="subtitle">Dual Roles of Surface Charge Screening and Pore Block </span>
Journal Articles

Regulation of Cloned Atp-Sensitive K Channels by Adenine Nucleotides and Sulfonylureas: Interactions between Sur1 and Positively Charged Domains on Kir6.2

Scott A. John, James N. Weiss, Bernard Ribalet
Journal: Journal of General Physiology
J Gen Physiol (2001) 118 (4): 391–406.
DOI: https://doi.org/10.1085/jgp.118.4.391
Published: 03 October 2001
View article titled, Regulation of Cloned Atp-Sensitive K Channels by Adenine Nucleotides and Sulfonylureas: <span class="subtitle">Interactions between Sur1 and Positively Charged Domains on Kir6.2</span>
Click here to open pdf in another window PDF for Regulation of Cloned Atp-Sensitive K Channels by Adenine Nucleotides and Sulfonylureas: <span class="subtitle">Interactions between Sur1 and Positively Charged Domains on Kir6.2</span>
Journal Articles

Regulation of Cloned Atp–Sensitive K Channels by Phosphorylation, Mgadp, and Phosphatidylinositol Bisphosphate (Pip2): A Study of Channel Rundown and Reactivation

Bernard Ribalet, Scott A. John, James N. Weiss
Journal: Journal of General Physiology
J Gen Physiol (2000) 116 (3): 391–410.
DOI: https://doi.org/10.1085/jgp.116.3.391
Published: 28 August 2000
View article titled, Regulation of Cloned Atp–Sensitive K Channels by Phosphorylation, Mgadp, and Phosphatidylinositol Bisphosphate (Pip<sub>2</sub>): <span class="subtitle">A Study of Channel Rundown and Reactivation</span>
Click here to open pdf in another window PDF for Regulation of Cloned Atp–Sensitive K Channels by Phosphorylation, Mgadp, and Phosphatidylinositol Bisphosphate (Pip<sub>2</sub>): <span class="subtitle">A Study of Channel Rundown and Reactivation</span>
Journal Articles

Novel Gating Mechanism of Polyamine Block in the Strong Inward Rectifier K Channel Kir2.1

Jong-Kook Lee, Scott A. John, James N. Weiss
Journal: Journal of General Physiology
J Gen Physiol (1999) 113 (4): 555–564.
DOI: https://doi.org/10.1085/jgp.113.4.555
Published: 01 April 1999
View article titled, Novel Gating Mechanism of Polyamine Block in the Strong Inward Rectifier K Channel Kir2.1
Click here to open pdf in another window PDF for Novel Gating Mechanism of Polyamine Block in the Strong Inward Rectifier K Channel Kir2.1