Issues

Cover picture: Laser scanning confocal image from a fluo-4–loaded, isolated E10 spontaneously active cardiomyocyte (left) with corresponding line-scan (yellow line) through the cytosol surrounding the nucleus (red n). Graphs above the line-scan image show relative calcium signals from near–sarcoplasmic reticulum (red line) and near-sarcolemma (blue line). Inset (gray background) shows both graphs in an expanded timescale from selected area below (gray; see article by Rapila et al., 397–405).