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Correction| August 01 1999

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Online ISSN: 1540-7748
Print ISSN: 0022-1295
© 1999 The Rockefeller University Press
1999
J Gen Physiol (1999) 114 (2): 337.
https://doi.org/10.1085/jgp.114.2.337
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This article has been corrected Gating Kinetics of Single Large-Conductance Ca2+-Activated K+ Channels in High Ca2+ Suggest a Two-Tiered Allosteric Gating Mechanism✪

Rothberg, B.S., and K.L. Magleby.

The Journal of General Physiology. Volume 114, No. 1, July 1999. 93–124.

Due to typesetting errors, Tables II–IV were printed incorrectly. The corrected tables appear below:

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© 1999 The Rockefeller University Press
1999
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TABLE II

Time Constants and Areas of Fitted Exponential Components at High Ca2+i

Component132 μM
1024 μM
τAreaτArea
 ms  ms  
Open distributions 
1 0.09 ± 0.04 0.062 ± 0.020 0.09 ± 0.03 0.057 ± 0.018 
2 1.85 ± 1.65 0.208 ± 0.149 1.64 ± 1.38 0.163 ± 0.116 
3 3.71 ± 2.01 0.772 ± 0.160 4.31 ± 1.88 0.813 ± 0.131 
Closed distributions 
1 0.03 ± 0.008 0.601 ± 0.019 0.02 ± 0.003 0.659 ± 0.058 
2 0.11 ± 0.06 0.276 ± 0.040 0.09 ± 0.03 0.235 ± 0.060 
3 0.35 ± 0.23 0.093 ± 0.038 0.42 ± 0.40 0.087 ± 0.032 
4 0.87 ± 0.27 0.028 ± 0.015 0.87 ± 0.19 0.022 ± 0.008 
5 4.2 ± 1.5 0.003 ± 0.003 4.5 ± 1.7 0.002 ± 0.002 
Component132 μM
1024 μM
τAreaτArea
 ms  ms  
Open distributions 
1 0.09 ± 0.04 0.062 ± 0.020 0.09 ± 0.03 0.057 ± 0.018 
2 1.85 ± 1.65 0.208 ± 0.149 1.64 ± 1.38 0.163 ± 0.116 
3 3.71 ± 2.01 0.772 ± 0.160 4.31 ± 1.88 0.813 ± 0.131 
Closed distributions 
1 0.03 ± 0.008 0.601 ± 0.019 0.02 ± 0.003 0.659 ± 0.058 
2 0.11 ± 0.06 0.276 ± 0.040 0.09 ± 0.03 0.235 ± 0.060 
3 0.35 ± 0.23 0.093 ± 0.038 0.42 ± 0.40 0.087 ± 0.032 
4 0.87 ± 0.27 0.028 ± 0.015 0.87 ± 0.19 0.022 ± 0.008 
5 4.2 ± 1.5 0.003 ± 0.003 4.5 ± 1.7 0.002 ± 0.002 

Values are means ± SD for five channels, except for open component 2, which is based on data from four channels.

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TABLE III

Normalized Likelihood Ratios (NLR10000) and Rankings (R) of Schemes IV–X

SchemeChannel 1 (B06)
Channel 2 (B12)
Channel 3 (B14)
NLR1000RNLR1000RNLR1000R
IV 3.15 × 10−33 6 8.66 × 10−30 6 3.63 × 10−41 6 
V 8.54 × 10−10 5 4.74 × 10−13 5 5.35 × 10−15 5 
VI 1.04 × 10−9 4 5.37 × 10−13 4 6.25 × 10−15 4 
V-sat 3.15 × 10−5 3 3.66 × 10−6 3 1.01 × 10−6 3 
VII 8.79 × 10−5 2 1.22 × 10−5 2 1.24 × 10−6 1 
X 3.25 × 10−4 1 1.24 × 10−5 1 1.25 × 10−6 2 
SchemeChannel 1 (B06)
Channel 2 (B12)
Channel 3 (B14)
NLR1000RNLR1000RNLR1000R
IV 3.15 × 10−33 6 8.66 × 10−30 6 3.63 × 10−41 6 
V 8.54 × 10−10 5 4.74 × 10−13 5 5.35 × 10−15 5 
VI 1.04 × 10−9 4 5.37 × 10−13 4 6.25 × 10−15 4 
V-sat 3.15 × 10−5 3 3.66 × 10−6 3 1.01 × 10−6 3 
VII 8.79 × 10−5 2 1.22 × 10−5 2 1.24 × 10−6 1 
X 3.25 × 10−4 1 1.24 × 10−5 1 1.25 × 10−6 2 

V-sat is Scheme V with saturation in the binding of Ca2+ for the data collected at 132 and 1,024 μM Ca2+i (see text).

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TABLE IV

Normalized Likelihood Ratios (NLR1000) and Rankings (R) of Schemes XI–XIV Fitted to Data Obtained at 1,024 μM Ca2+i

SchemeChannel 1 (B06)
Channel 2 (B12)
Channel 3 (B14)
NLR1000RNLR1000RNLR1000R
XIV 2.11 × 10−4 4 2.24 × 10−5 4 1.00 × 10−3 4 
XI 0.0610 3 0.117 3 0.238 3 
XIII 0.468 2 0.950 2 0.828 2 
XII 0.475 1 0.959 1 0.899 1 
SchemeChannel 1 (B06)
Channel 2 (B12)
Channel 3 (B14)
NLR1000RNLR1000RNLR1000R
XIV 2.11 × 10−4 4 2.24 × 10−5 4 1.00 × 10−3 4 
XI 0.0610 3 0.117 3 0.238 3 
XIII 0.468 2 0.950 2 0.828 2 
XII 0.475 1 0.959 1 0.899 1 
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Contents

Volume 114, Issue 2
1 August 1999
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