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Rothberg, B.S., and K.L. Magleby.
The Journal of General Physiology. Volume 114, No. 1, July 1999. 93–124.
Due to typesetting errors, Tables II–IV were printed incorrectly. The corrected tables appear below:
TABLE II
Time Constants and Areas of Fitted Exponential Components at High Ca2+i
| Component . | 132 μM . | 1024 μM . | ||
|---|---|---|---|---|
| τ . | Area . | τ . | Area . | |
| ms | ms | |||
| Open distributions | ||||
| 1 | 0.09 ± 0.04 | 0.062 ± 0.020 | 0.09 ± 0.03 | 0.057 ± 0.018 |
| 2 | 1.85 ± 1.65 | 0.208 ± 0.149 | 1.64 ± 1.38 | 0.163 ± 0.116 |
| 3 | 3.71 ± 2.01 | 0.772 ± 0.160 | 4.31 ± 1.88 | 0.813 ± 0.131 |
| Closed distributions | ||||
| 1 | 0.03 ± 0.008 | 0.601 ± 0.019 | 0.02 ± 0.003 | 0.659 ± 0.058 |
| 2 | 0.11 ± 0.06 | 0.276 ± 0.040 | 0.09 ± 0.03 | 0.235 ± 0.060 |
| 3 | 0.35 ± 0.23 | 0.093 ± 0.038 | 0.42 ± 0.40 | 0.087 ± 0.032 |
| 4 | 0.87 ± 0.27 | 0.028 ± 0.015 | 0.87 ± 0.19 | 0.022 ± 0.008 |
| 5 | 4.2 ± 1.5 | 0.003 ± 0.003 | 4.5 ± 1.7 | 0.002 ± 0.002 |
| Component . | 132 μM . | 1024 μM . | ||
|---|---|---|---|---|
| τ . | Area . | τ . | Area . | |
| ms | ms | |||
| Open distributions | ||||
| 1 | 0.09 ± 0.04 | 0.062 ± 0.020 | 0.09 ± 0.03 | 0.057 ± 0.018 |
| 2 | 1.85 ± 1.65 | 0.208 ± 0.149 | 1.64 ± 1.38 | 0.163 ± 0.116 |
| 3 | 3.71 ± 2.01 | 0.772 ± 0.160 | 4.31 ± 1.88 | 0.813 ± 0.131 |
| Closed distributions | ||||
| 1 | 0.03 ± 0.008 | 0.601 ± 0.019 | 0.02 ± 0.003 | 0.659 ± 0.058 |
| 2 | 0.11 ± 0.06 | 0.276 ± 0.040 | 0.09 ± 0.03 | 0.235 ± 0.060 |
| 3 | 0.35 ± 0.23 | 0.093 ± 0.038 | 0.42 ± 0.40 | 0.087 ± 0.032 |
| 4 | 0.87 ± 0.27 | 0.028 ± 0.015 | 0.87 ± 0.19 | 0.022 ± 0.008 |
| 5 | 4.2 ± 1.5 | 0.003 ± 0.003 | 4.5 ± 1.7 | 0.002 ± 0.002 |
Values are means ± SD for five channels, except for open component 2, which is based on data from four channels.
TABLE III
Normalized Likelihood Ratios (NLR10000) and Rankings (R) of Schemes IV–X
| Scheme . | Channel 1 (B06) . | Channel 2 (B12) . | Channel 3 (B14) . | |||
|---|---|---|---|---|---|---|
| NLR1000 . | R . | NLR1000 . | R . | NLR1000 . | R . | |
| IV | 3.15 × 10−33 | 6 | 8.66 × 10−30 | 6 | 3.63 × 10−41 | 6 |
| V | 8.54 × 10−10 | 5 | 4.74 × 10−13 | 5 | 5.35 × 10−15 | 5 |
| VI | 1.04 × 10−9 | 4 | 5.37 × 10−13 | 4 | 6.25 × 10−15 | 4 |
| V-sat | 3.15 × 10−5 | 3 | 3.66 × 10−6 | 3 | 1.01 × 10−6 | 3 |
| VII | 8.79 × 10−5 | 2 | 1.22 × 10−5 | 2 | 1.24 × 10−6 | 1 |
| X | 3.25 × 10−4 | 1 | 1.24 × 10−5 | 1 | 1.25 × 10−6 | 2 |
| Scheme . | Channel 1 (B06) . | Channel 2 (B12) . | Channel 3 (B14) . | |||
|---|---|---|---|---|---|---|
| NLR1000 . | R . | NLR1000 . | R . | NLR1000 . | R . | |
| IV | 3.15 × 10−33 | 6 | 8.66 × 10−30 | 6 | 3.63 × 10−41 | 6 |
| V | 8.54 × 10−10 | 5 | 4.74 × 10−13 | 5 | 5.35 × 10−15 | 5 |
| VI | 1.04 × 10−9 | 4 | 5.37 × 10−13 | 4 | 6.25 × 10−15 | 4 |
| V-sat | 3.15 × 10−5 | 3 | 3.66 × 10−6 | 3 | 1.01 × 10−6 | 3 |
| VII | 8.79 × 10−5 | 2 | 1.22 × 10−5 | 2 | 1.24 × 10−6 | 1 |
| X | 3.25 × 10−4 | 1 | 1.24 × 10−5 | 1 | 1.25 × 10−6 | 2 |
V-sat is Scheme V with saturation in the binding of Ca2+ for the data collected at 132 and 1,024 μM Ca2+i (see text).
TABLE IV
Normalized Likelihood Ratios (NLR1000) and Rankings (R) of Schemes XI–XIV Fitted to Data Obtained at 1,024 μM Ca2+i
| Scheme . | Channel 1 (B06) . | Channel 2 (B12) . | Channel 3 (B14) . | |||
|---|---|---|---|---|---|---|
| NLR1000 . | R . | NLR1000 . | R . | NLR1000 . | R . | |
| XIV | 2.11 × 10−4 | 4 | 2.24 × 10−5 | 4 | 1.00 × 10−3 | 4 |
| XI | 0.0610 | 3 | 0.117 | 3 | 0.238 | 3 |
| XIII | 0.468 | 2 | 0.950 | 2 | 0.828 | 2 |
| XII | 0.475 | 1 | 0.959 | 1 | 0.899 | 1 |
| Scheme . | Channel 1 (B06) . | Channel 2 (B12) . | Channel 3 (B14) . | |||
|---|---|---|---|---|---|---|
| NLR1000 . | R . | NLR1000 . | R . | NLR1000 . | R . | |
| XIV | 2.11 × 10−4 | 4 | 2.24 × 10−5 | 4 | 1.00 × 10−3 | 4 |
| XI | 0.0610 | 3 | 0.117 | 3 | 0.238 | 3 |
| XIII | 0.468 | 2 | 0.950 | 2 | 0.828 | 2 |
| XII | 0.475 | 1 | 0.959 | 1 | 0.899 | 1 |
© 1999 The Rockefeller University Press
1999
