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Journal Articles

Dynamic Foxp3–chromatin interaction controls tunable Treg cell function

In Special Collection:
Autoimmunity 2024
Minghong He, Xinying Zong, Beisi Xu, Wenjie Qi, Wenjun Huang, Mohamed Nadhir Djekidel, Yang Zhang, Vishwajeeth R. Pagala, Jun Li, Xiaolei Hao, Clifford Guy, Lu Bai, Richard Cross, Chunliang Li, Junmin Peng, Yongqiang Feng
Journal: Journal of Experimental Medicine
J Exp Med (2024) 221 (9): e20232068.
https://doi.org/10.1084/jem.20232068
Published: 27 June 2024
View article titled, Dynamic Foxp3–chromatin interaction controls tunable Treg cell function
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Includes: Supplementary data
Journal Articles

IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation

In Special Collection:
Cytokines Collection 2023
Lina Petersone, Chun Jing Wang, Natalie M. Edner, Astrid Fabri, Spyridoula-Angeliki Nikou, Claudia Hinze, Ellen M. Ross, Elisavet Ntavli, Yassin Elfaki, Frank Heuts, Vitalijs Ovcinnikovs, Andrea Rueda Gonzalez, Luke P. Houghton, Hannah M. Li, Yang Zhang, Kai-Michael Toellner, Lucy S.K. Walker
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (10): e20221653.
https://doi.org/10.1084/jem.20221653
Published: 19 July 2023
View article titled, IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation
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Includes: Supplementary data
Journal Articles

CCL17 acts as a novel therapeutic target in pathological cardiac hypertrophy and heart failure

In Special Collection:
Fibrosis Collection 2023
Yang Zhang, Yicong Ye, Xiaoqiang Tang, Hui Wang, Toshiko Tanaka, Ran Tian, Xufei Yang, Lun Wang, Ying Xiao, Xiaomin Hu, Ye Jin, Haiyu Pang, Tian Du, Honghong Liu, Lihong Sun, Shuo Xiao, Ruijia Dong, Luigi Ferrucci, Zhuang Tian, Shuyang Zhang
Journal: Journal of Experimental Medicine
J Exp Med (2022) 219 (8): e20200418.
https://doi.org/10.1084/jem.20200418
Published: 10 June 2022
View article titled, CCL17 acts as a novel therapeutic target in pathological cardiac hypertrophy and heart failure
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Includes: Supplementary data
Journal Articles

Germinal center derived B cell memory without T cells

Yang Zhang, Kai-Michael Toellner
Journal: Journal of Experimental Medicine
J Exp Med (2022) 219 (3): e20220012.
https://doi.org/10.1084/jem.20220012
Published: 16 February 2022
View article titled, Germinal center derived B cell memory without T cells
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Journal Articles

Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation

In Special Collection:
Stem Cell Collection 2022
Nouraiz Ahmed, Martin Etzrodt, Philip Dettinger, Tobias Kull, Dirk Loeffler, Philipp S. Hoppe, James S. Chavez, Yang Zhang, Germán Camargo Ortega, Oliver Hilsenbeck, Hideaki Nakajima, Eric M. Pietras, Timm Schroeder
Journal: Journal of Experimental Medicine
J Exp Med (2021) 219 (1): e20202490.
https://doi.org/10.1084/jem.20202490
Published: 24 November 2021
View article titled, Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation
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Journal Articles

Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF

Annika Hausmann, Boas Felmy, Leo Kunz, Sanne Kroon, Dorothée Lisa Berthold, Giverny Ganz, Ioana Sandu, Toshihiro Nakamura, Nathan Sébastien Zangger, Yang Zhang, Tamas Dolowschiak, Stefan Alexander Fattinger, Markus Furter, Anna Angelika Müller-Hauser, Manja Barthel, Katerina Vlantis, Laurens Wachsmuth, Jan Kisielow, Luigi Tortola, Danijela Heide, Mathias Heikenwälder, Annette Oxenius, Manfred Kopf, Timm Schroeder, Manolis Pasparakis, Mikael Erik Sellin, Wolf-Dietrich Hardt
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (11): e20210862.
https://doi.org/10.1084/jem.20210862
Published: 16 September 2021
View article titled, Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF
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Journal Articles

Foxp3 enhancers synergize to maximize regulatory T cell suppressive capacity

Xinying Zong, Xiaolei Hao, Beisi Xu, Jeremy Chase Crawford, Shaela Wright, Jun Li, Yang Zhang, Lu Bai, Minghong He, Menglin Jiang, Yiping Fan, Jon P. Connelly, Shondra M. Pruett-Miller, Hartmut Berns, Laura Janke, Chunliang Li, Yongqiang Feng
Journal: Journal of Experimental Medicine
J Exp Med (2021) 218 (8): e20202415.
https://doi.org/10.1084/jem.20202415
Published: 04 June 2021
View article titled, <em>Foxp3</em> enhancers synergize to maximize regulatory T cell suppressive capacity
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Includes: Supplementary data
Journal Articles

Histone methyltransferase Nsd2 is required for follicular helper T cell differentiation

In Special Collection:
2020 Germinal Centers and Immune Niches
Xuehui Long, Le Zhang, Yang Zhang, Min Min, Bichun Lin, Jingjing Chen, Xiaojie Ma, Sulan Zhai, Zhenming Cai, Yingxia Liu, Yanlai Lu, Nan Che, Wenfeng Tan, Jun Qin, Xiaoming Wang
Journal: Journal of Experimental Medicine
J Exp Med (2019) 217 (1): e20190832.
https://doi.org/10.1084/jem.20190832
Published: 21 October 2019
View article titled, Histone methyltransferase Nsd2 is required for follicular helper T cell differentiation
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Includes: Supplementary data
Journal Articles

Caveolin-1 selectively regulates microRNA sorting into microvesicles after noxious stimuli

Heedoo Lee, Chunhua Li, Yang Zhang, Duo Zhang, Leo E. Otterbein, Yang Jin
Journal: Journal of Experimental Medicine
J Exp Med (2019) 216 (9): 2202–2220.
https://doi.org/10.1084/jem.20182313
Published: 24 June 2019
View article titled, Caveolin-1 selectively regulates microRNA sorting into microvesicles after noxious stimuli
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Includes: Supplementary data
Journal Articles

Sphingosine-1-phosphate receptor 2 restrains egress of γδ T cells from the skin

In Special Collection:
A Collection for the 59th Midwinter Conference of Immunologists at Asilomar , JEM Immunology Collection 2020
Brian J. Laidlaw, Elizabeth E. Gray, Yang Zhang, Francisco Ramírez-Valle, Jason G. Cyster
Journal: Journal of Experimental Medicine
J Exp Med (2019) 216 (7): 1487–1496.
https://doi.org/10.1084/jem.20190114
Published: 03 June 2019
View article titled, Sphingosine-1-phosphate receptor 2 restrains egress of γδ T cells from the skin
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Includes: Supplementary data
Journal Articles

Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells

In Special Collection:
B Cells: Mechanisms in Immunity and Autoimmunity
Yang Zhang, Laura Tech, Laura A. George, Andreas Acs, Russell E. Durrett, Henry Hess, Lucy S.K. Walker, David M. Tarlinton, Anne L. Fletcher, Anja Erika Hauser, Kai-Michael Toellner
Journal: Journal of Experimental Medicine
J Exp Med (2018) 215 (4): 1227–1243.
https://doi.org/10.1084/jem.20160832
Published: 16 March 2018
View article titled, Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells
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Includes: Supplementary data
Journal Articles

Germinal center B cells govern their own fate via antibody feedback

Yang Zhang, Michael Meyer-Hermann, Laura A. George, Marc Thilo Figge, Mahmood Khan, Margaret Goodall, Stephen P. Young, Adam Reynolds, Francesco Falciani, Ari Waisman, Clare A. Notley, Michael R. Ehrenstein, Marie Kosco-Vilbois, Kai-Michael Toellner
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (3): 457–464.
https://doi.org/10.1084/jem.20120150
Published: 18 February 2013
View article titled, Germinal center B cells govern their own fate via antibody feedback
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Journal Articles

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanism

Dimitra Zotos, Jonathan M. Coquet, Yang Zhang, Amanda Light, Kathy D'Costa, Axel Kallies, Lynn M. Corcoran, Dale I. Godfrey, Kai-Michael Toellner, Mark J. Smyth, Stephen L. Nutt, David M. Tarlinton
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (2): 365–378.
https://doi.org/10.1084/jem.20091777
Published: 08 February 2010
View article titled, IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanism
Open the PDF for IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanism in another window
Includes: Supplementary data