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Journal Articles

TLR7-dependent and FcγR-independent production of type I interferon in experimental mouse lupus

Pui Y. Lee, Yutaro Kumagai, Yi Li, Osamu Takeuchi, Hideo Yoshida, Jason Weinstein, Erinn S. Kellner, Dina Nacionales, Tolga Barker, Kindra Kelly-Scumpia, Nico van Rooijen, Himanshu Kumar, Taro Kawai, Minoru Satoh, Shizuo Akira, Westley H. Reeves

J Exp Med (2008) 205 (13): 2995–3006.

https://doi.org/10.1084/jem.20080462

Published: 01 December 2008

View article titled, TLR7-dependent and FcγR-independent production of type I interferon in experimental mouse lupus

Includes: Supplementary data

Journal Articles

Enhanced TLR-mediated NF-IL6–dependent gene expression by Trib1 deficiency

Masahiro Yamamoto, Satoshi Uematsu, Toru Okamoto, Yoshiharu Matsuura, Shintaro Sato, Himanshu Kumar, Takashi Satoh, Tatsuya Saitoh, Kiyoshi Takeda, Ken J. Ishii, Osamu Takeuchi, Taro Kawai, Shizuo Akira

J Exp Med (2007) 204 (9): 2233–2239.

https://doi.org/10.1084/jem.20070183

Published: 27 August 2007

View article titled, Enhanced TLR-mediated NF-IL6–dependent gene expression by Trib1 deficiency

Includes: Supplementary data

Journal Articles

The chemotherapeutic agent DMXAA potently and specifically activates the TBK1–IRF-3 signaling axis

Zachary J. Roberts, Nadege Goutagny, Pin-Yu Perera, Hiroki Kato, Himanshu Kumar, Taro Kawai, Shizuo Akira, Ram Savan, David van Echo, Katherine A. Fitzgerald, Howard A. Young, Lai-Ming Ching, Stefanie N. Vogel

J Exp Med (2007) 204 (7): 1559–1569.

https://doi.org/10.1084/jem.20061845

Published: 11 June 2007

View article titled, The chemotherapeutic agent DMXAA potently and specifically activates the TBK1–IRF-3 signaling axis

Includes: Supplementary data

Journal Articles

Essential role of IPS-1 in innate immune responses against RNA viruses

Himanshu Kumar, Taro Kawai, Hiroki Kato, Shintaro Sato, Ken Takahashi, Cevayir Coban, Masahiro Yamamoto, Satoshi Uematsu, Ken J. Ishii, Osamu Takeuchi, Shizuo Akira

J Exp Med (2006) 203 (7): 1795–1803.

https://doi.org/10.1084/jem.20060792

Published: 19 June 2006

View article titled, Essential role of IPS-1 in innate immune responses against RNA viruses

Includes: Supplementary data

Journal Articles

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction

Satoshi Uematsu, Shintaro Sato, Masahiro Yamamoto, Tomonori Hirotani, Hiroki Kato, Fumihiko Takeshita, Michiyuki Matsuda, Cevayir Coban, Ken J. Ishii, Taro Kawai, Osamu Takeuchi, Shizuo Akira

J Exp Med (2005) 201 (6): 915–923.

https://doi.org/10.1084/jem.20042372

Published: 14 March 2005

View article titled, Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction

Journal Articles

Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin

Cevayir Coban, Ken J. Ishii, Taro Kawai, Hiroaki Hemmi, Shintaro Sato, Satoshi Uematsu, Masahiro Yamamoto, Osamu Takeuchi, Sawako Itagaki, Nirbhay Kumar, Toshihiro Horii, Shizuo Akira

J Exp Med (2005) 201 (1): 19–25.

https://doi.org/10.1084/jem.20041836

Published: 03 January 2005

View article titled, Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin

Journal Articles

The Roles of Two IκB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection

Hiroaki Hemmi, Osamu Takeuchi, Shintaro Sato, Masahiro Yamamoto, Tsuneyasu Kaisho, Hideki Sanjo, Taro Kawai, Katsuaki Hoshino, Kiyoshi Takeda, Shizuo Akira

J Exp Med (2004) 199 (12): 1641–1650.

https://doi.org/10.1084/jem.20040520

Published: 21 June 2004

View article titled, The Roles of Two IκB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection

Journal Articles

Iκb Kinase α Is Essential for Mature B Cell Development and Function

Tsuneyasu Kaisho, Kiyoshi Takeda, Tohru Tsujimura, Taro Kawai, Fumiko Nomura, Nobuyuki Terada, Shizuo Akira

J Exp Med (2001) 193 (4): 417–426.

https://doi.org/10.1084/jem.193.4.417

Published: 12 February 2001

View article titled, Iκb Kinase α Is Essential for Mature B Cell Development and Function

Journal Articles

Impairment of Natural Killer Cytotoxic Activity and Interferon γ Production in Ccaat/Enhancer Binding Protein γ–Deficient Mice

Tsuneyasu Kaisho, Hiroko Tsutsui, Takashi Tanaka, Tohru Tsujimura, Kiyoshi Takeda, Taro Kawai, Nobuaki Yoshida, Kenji Nakanishi, Shizuo Akira

J Exp Med (1999) 190 (11): 1573–1582.

https://doi.org/10.1084/jem.190.11.1573

Published: 06 December 1999

View article titled, Impairment of Natural Killer Cytotoxic Activity and Interferon γ Production in Ccaat/Enhancer Binding Protein γ–Deficient Mice

NARROW

TLR7-dependent and FcγR-independent production of type I interferon in experimental mouse lupus

Enhanced TLR-mediated NF-IL6–dependent gene expression by Trib1 deficiency

The chemotherapeutic agent DMXAA potently and specifically activates the TBK1–IRF-3 signaling axis

Essential role of IPS-1 in innate immune responses against RNA viruses

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction

Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin

The Roles of Two IκB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection

Iκb Kinase α Is Essential for Mature B Cell Development and Function

Impairment of Natural Killer Cytotoxic Activity and Interferon γ Production in Ccaat/Enhancer Binding Protein γ–Deficient Mice

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