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Journal Articles

Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner

In Special Collection:
Innate Immune Cells and Signaling 2023
Tina Schumann, Santiago Costas Ramon, Nadja Schubert, Mohamad Aref Mayo, Melanie Hega, Katharina Isabell Maser, Servi-Remzi Ada, Lukas Sydow, Mona Hajikazemi, Markus Badstübner, Patrick Müller, Yan Ge, Farhad Shakeri, Andreas Buness, Benjamin Rupf, Stefan Lienenklaus, Barbara Utess, Lina Muhandes, Michael Haase, Luise Rupp, Marc Schmitz, Thomas Gramberg, Nicolas Manel, Gunther Hartmann, Thomas Zillinger, Hiroki Kato, Stefan Bauer, Alexander Gerbaulet, Katrin Paeschke, Axel Roers, Rayk Behrendt
Journal: Journal of Experimental Medicine
J Exp Med (2022) 220 (1): e20220829.
https://doi.org/10.1084/jem.20220829
Published: 08 November 2022
View article titled, Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner
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Includes: Supplementary data
Journal Articles

Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging

York Kamenisch, Maria Fousteri, Jennifer Knoch, Anna-Katharina von Thaler, Birgit Fehrenbacher, Hiroki Kato, Thomas Becker, Martijn E.T. Dollé, Raoul Kuiper, Marc Majora, Martin Schaller, Gijsbertus T.J. van der Horst, Harry van Steeg, Martin Röcken, Doron Rapaport, Jean Krutmann, Leon H. Mullenders, Mark Berneburg
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (2): 379–390.
https://doi.org/10.1084/jem.20091834
Published: 25 January 2010
View article titled, Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging
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Includes: Supplementary data
Journal Articles

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

Hiroki Kato, Osamu Takeuchi, Eriko Mikamo-Satoh, Reiko Hirai, Tomoji Kawai, Kazufumi Matsushita, Akane Hiiragi, Terence S. Dermody, Takashi Fujita, Shizuo Akira
Journal: Journal of Experimental Medicine
J Exp Med (2008) 205 (7): 1601–1610.
https://doi.org/10.1084/jem.20080091
Published: 30 June 2008
View article titled, Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5
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Includes: Supplementary data
Journal Articles

The chemotherapeutic agent DMXAA potently and specifically activates the TBK1–IRF-3 signaling axis

Zachary J. Roberts, Nadege Goutagny, Pin-Yu Perera, Hiroki Kato, Himanshu Kumar, Taro Kawai, Shizuo Akira, Ram Savan, David van Echo, Katherine A. Fitzgerald, Howard A. Young, Lai-Ming Ching, Stefanie N. Vogel
Journal: Journal of Experimental Medicine
J Exp Med (2007) 204 (7): 1559–1569.
https://doi.org/10.1084/jem.20061845
Published: 11 June 2007
View article titled, The chemotherapeutic agent DMXAA potently and specifically activates the TBK1–IRF-3 signaling axis
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Includes: Supplementary data
Journal Articles

Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor–mediated immune responses but not in TCR signaling

Tatsukata Kawagoe, Shintaro Sato, Andreas Jung, Masahiro Yamamoto, Kosuke Matsui, Hiroki Kato, Satoshi Uematsu, Osamu Takeuchi, Shizuo Akira
Journal: Journal of Experimental Medicine
J Exp Med (2007) 204 (5): 1013–1024.
https://doi.org/10.1084/jem.20061523
Published: 07 May 2007
View article titled, Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor–mediated immune responses but not in TCR signaling
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Includes: Supplementary data
Journal Articles

Essential role of IPS-1 in innate immune responses against RNA viruses

Himanshu Kumar, Taro Kawai, Hiroki Kato, Shintaro Sato, Ken Takahashi, Cevayir Coban, Masahiro Yamamoto, Satoshi Uematsu, Ken J. Ishii, Osamu Takeuchi, Shizuo Akira
Journal: Journal of Experimental Medicine
J Exp Med (2006) 203 (7): 1795–1803.
https://doi.org/10.1084/jem.20060792
Published: 19 June 2006
View article titled, Essential role of IPS-1 in innate immune responses against RNA viruses
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Includes: Supplementary data
Journal Articles

Dendritic cells star in Vancouver

Eynav Klechevsky, Hiroki Kato, Anne-Marit Sponaas
Journal: Journal of Experimental Medicine
J Exp Med (2005) 202 (1): 5–10.
https://doi.org/10.1084/jem.20050566
Published: 05 July 2005
View article titled, Dendritic cells star in Vancouver
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Journal Articles

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction

Satoshi Uematsu, Shintaro Sato, Masahiro Yamamoto, Tomonori Hirotani, Hiroki Kato, Fumihiko Takeshita, Michiyuki Matsuda, Cevayir Coban, Ken J. Ishii, Taro Kawai, Osamu Takeuchi, Shizuo Akira
Journal: Journal of Experimental Medicine
J Exp Med (2005) 201 (6): 915–923.
https://doi.org/10.1084/jem.20042372
Published: 14 March 2005
View article titled, Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction
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