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Journal Articles

Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection

Amanda J. Lee, Branson Chen, Marianne V. Chew, Nicole G. Barra, Mira M. Shenouda, Tina Nham, Nico van Rooijen, Manel Jordana, Karen L. Mossman, Robert D. Schreiber, Matthias Mack, Ali A. Ashkar

J Exp Med (2017) 214 (4): 1153–1167.

https://doi.org/10.1084/jem.20160880

Published: 06 March 2017

View article titled, Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection

Journal Articles

CD68 acts as a major gateway for malaria sporozoite liver infection

Sung-Jae Cha, Kiwon Park, Prakash Srinivasan, Christian W. Schindler, Nico van Rooijen, Monique Stins, Marcelo Jacobs-Lorena

J Exp Med (2015) 212 (9): 1391–1403.

https://doi.org/10.1084/jem.20110575

Published: 27 July 2015

View article titled, CD68 acts as a major gateway for malaria sporozoite liver infection

Journal Articles

Role of host cell traversal by the malaria sporozoite during liver infection

Joana Tavares, Pauline Formaglio, Sabine Thiberge, Elodie Mordelet, Nico Van Rooijen, Alexander Medvinsky, Robert Ménard, Rogerio Amino

J Exp Med (2013) 210 (5): 905–915.

https://doi.org/10.1084/jem.20121130

Published: 22 April 2013

View article titled, Role of host cell traversal by the malaria sporozoite during liver infection

Journal Articles

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation

Claus-Werner Franzke, Cristina Cobzaru, Antigoni Triantafyllopoulou, Stefanie Löffek, Keisuke Horiuchi, David W. Threadgill, Thomas Kurz, Nico van Rooijen, Leena Bruckner-Tuderman, Carl P. Blobel

J Exp Med (2012) 209 (13): 2517.

https://doi.org/10.1084/jem.2011225820913c

Published: 26 November 2012

View article titled, Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation

Journal Articles

Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts

Alexandre P.A. Theocharides, Liqing Jin, Po-Yan Cheng, Tatiana K. Prasolava, Andrei V. Malko, Jenny M. Ho, Armando G. Poeppl, Nico van Rooijen, Mark D. Minden, Jayne S. Danska, John E. Dick, Jean C.Y. Wang

J Exp Med (2012) 209 (10): 1883–1899.

https://doi.org/10.1084/jem.20120502

Published: 03 September 2012

View article titled, Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts

Journal Articles

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand–dependent terminal keratinocyte differentiation

Claus-Werner Franzke, Cristina Cobzaru, Antigoni Triantafyllopoulou, Stefanie Löffek, Keisuke Horiuchi, David W. Threadgill, Thomas Kurz, Nico van Rooijen, Leena Bruckner-Tuderman, Carl P. Blobel

J Exp Med (2012) 209 (6): 1105–1119.

https://doi.org/10.1084/jem.20112258

Published: 07 May 2012

View article titled, Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand–dependent terminal keratinocyte differentiation

Includes: Supplementary data

Journal Articles

MHC class I–specific antibody binding to nonhematopoietic cells drives complement activation to induce transfusion-related acute lung injury in mice

Richard T. Strait, Wyenona Hicks, Nathaniel Barasa, Ashley Mahler, Marat Khodoun, Jörg Köhl, Keith Stringer, David Witte, Nico Van Rooijen, Brian M. Susskind, Fred D. Finkelman

J Exp Med (2011) 208 (12): 2525–2544.

https://doi.org/10.1084/jem.20110159

Published: 24 October 2011

View article titled, MHC class I–specific antibody binding to nonhematopoietic cells drives complement activation to induce transfusion-related acute lung injury in mice

Journal Articles

Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation

Daigo Hashimoto, Andrew Chow, Melanie Greter, Yvonne Saenger, Wing-Hong Kwan, Marylene Leboeuf, Florent Ginhoux, Jordi C. Ochando, Yuya Kunisaki, Nico van Rooijen, Chen Liu, Takanori Teshima, Peter S. Heeger, E. Richard Stanley, Paul S. Frenette, Miriam Merad

J Exp Med (2011) 208 (5): 1069–1082.

https://doi.org/10.1084/jem.20101709

Published: 02 May 2011

View article titled, Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation

Includes: Supplementary data

Journal Articles

Bone marrow CD169⁺ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

Andrew Chow, Daniel Lucas, Andrés Hidalgo, Simón Méndez-Ferrer, Daigo Hashimoto, Christoph Scheiermann, Michela Battista, Marylene Leboeuf, Colette Prophete, Nico van Rooijen, Masato Tanaka, Miriam Merad, Paul S. Frenette

J Exp Med (2011) 208 (2): 261–271.

https://doi.org/10.1084/jem.20101688

Published: 31 January 2011

View article titled, Bone marrow CD169<sup>+</sup> macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

Includes: Supplementary data

Journal Articles

IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection

Jodi McGill, Nico Van Rooijen, Kevin L. Legge

J Exp Med (2010) 207 (3): 521–534.

https://doi.org/10.1084/jem.20091711

Published: 08 March 2010

View article titled, IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection

Includes: Supplementary data

Journal Articles

MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries

Paul C.Y. Tang, Lingfeng Qin, Jacek Zielonka, Jing Zhou, Catherine Matte-Martone, Sonia Bergaya, Nico van Rooijen, Warren D. Shlomchik, Wang Min, William C. Sessa, Jordan S. Pober, George Tellides

J Exp Med (2008) 205 (13): 3159–3171.

https://doi.org/10.1084/jem.20081298

Published: 08 December 2008

View article titled, MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries

Includes: Supplementary data

Journal Articles

TLR7-dependent and FcγR-independent production of type I interferon in experimental mouse lupus

Pui Y. Lee, Yutaro Kumagai, Yi Li, Osamu Takeuchi, Hideo Yoshida, Jason Weinstein, Erinn S. Kellner, Dina Nacionales, Tolga Barker, Kindra Kelly-Scumpia, Nico van Rooijen, Himanshu Kumar, Taro Kawai, Minoru Satoh, Shizuo Akira, Westley H. Reeves

J Exp Med (2008) 205 (13): 2995–3006.

https://doi.org/10.1084/jem.20080462

Published: 01 December 2008

View article titled, TLR7-dependent and FcγR-independent production of type I interferon in experimental mouse lupus

Includes: Supplementary data

Journal Articles

Ly6c⁺ “inflammatory monocytes” are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis

Daniel R. Getts, Rachael L. Terry, Meghann Teague Getts, Marcus Müller, Sabita Rana, Bimmi Shrestha, Jane Radford, Nico Van Rooijen, Iain L. Campbell, Nicholas J.C. King

J Exp Med (2008) 205 (10): 2319–2337.

https://doi.org/10.1084/jem.20080421

Published: 08 September 2008

View article titled, Ly6c<sup>+</sup> “inflammatory monocytes” are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis

Includes: Supplementary data

Journal Articles

Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs

Jodi McGill, Nico Van Rooijen, Kevin L. Legge

J Exp Med (2008) 205 (7): 1635–1646.

https://doi.org/10.1084/jem.20080314

Published: 30 June 2008

View article titled, Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs

Includes: Supplementary data

Journal Articles

An antigen-specific pathway for CD8 T cells across the blood-brain barrier

Ian Galea, Martine Bernardes-Silva, Penny A. Forse, Nico van Rooijen, Roland S. Liblau, V. Hugh Perry

J Exp Med (2007) 204 (9): 2023–2030.

https://doi.org/10.1084/jem.20070064

Published: 06 August 2007

View article titled, An antigen-specific pathway for CD8 T cells across the blood-brain barrier

Journal Articles

Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis

Ludovic Arnold, Adeline Henry, Françoise Poron, Yasmine Baba-Amer, Nico van Rooijen, Anne Plonquet, Romain K. Gherardi, Bénédicte Chazaud

J Exp Med (2007) 204 (5): 1057–1069.

https://doi.org/10.1084/jem.20070075

Published: 07 May 2007

View article titled, Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis

Journal Articles

Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis

Smriti Agrawal, Per Anderson, Madeleine Durbeej, Nico van Rooijen, Fredrik Ivars, Ghislain Opdenakker, Lydia M. Sorokin

J Exp Med (2006) 203 (4): 1007–1019.

https://doi.org/10.1084/jem.20051342

Published: 03 April 2006

View article titled, Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis

Journal Articles

Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery

Frank Tacke, Florent Ginhoux, Claudia Jakubzick, Nico van Rooijen, Miriam Merad, Gwendalyn J. Randolph

J Exp Med (2006) 203 (3): 583–597.

https://doi.org/10.1084/jem.20052119

Published: 21 February 2006

View article titled, Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery

Includes: Supplementary data

Journal Articles

Role of CCR8 and Other Chemokine Pathways in the Migration of Monocyte-derived Dendritic Cells to Lymph Nodes

Chunfeng Qu, Emmerson W. Edwards, Frank Tacke, Véronique Angeli, Jaime Llodrá, Guzman Sanchez-Schmitz, Alexandre Garin, Nasreen S. Haque, Wendy Peters, Nico van Rooijen, Carmen Sanchez-Torres, Jonathan Bromberg, Israel F. Charo, Steffen Jung, Sergio A. Lira, Gwendalyn J. Randolph

J Exp Med (2004) 200 (10): 1231–1241.

https://doi.org/10.1084/jem.20032152

Published: 08 November 2004

View article titled, Role of CCR8 and Other Chemokine Pathways in the Migration of Monocyte-derived Dendritic Cells to Lymph Nodes

Includes: Supplementary data

Journal Articles

A Conduit System Distributes Chemokines and Small Blood-borne Molecules through the Splenic White Pulp

Martijn A. Nolte, Jeroen A.M. Beliën, Inge Schadee-Eestermans, Wendy Jansen, Wendy W.J. Unger, Nico van Rooijen, Georg Kraal, Reina E. Mebius

J Exp Med (2003) 198 (3): 505–512.

https://doi.org/10.1084/jem.20021801

Published: 04 August 2003

View article titled, A Conduit System Distributes Chemokines and Small Blood-borne Molecules through the Splenic White Pulp

NARROW

Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection

CD68 acts as a major gateway for malaria sporozoite liver infection

Role of host cell traversal by the malaria sporozoite during liver infection

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation

Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand–dependent terminal keratinocyte differentiation

MHC class I–specific antibody binding to nonhematopoietic cells drives complement activation to induce transfusion-related acute lung injury in mice

Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation

Bone marrow CD169⁺ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection

MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries

TLR7-dependent and FcγR-independent production of type I interferon in experimental mouse lupus

Ly6c⁺ “inflammatory monocytes” are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis

Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs

An antigen-specific pathway for CD8 T cells across the blood-brain barrier

Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis

Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis

Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery

Role of CCR8 and Other Chemokine Pathways in the Migration of Monocyte-derived Dendritic Cells to Lymph Nodes

A Conduit System Distributes Chemokines and Small Blood-borne Molecules through the Splenic White Pulp

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