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Journal Articles

Suppression of arthritis by an inhibitor of nitric oxide synthase.

N McCartney-Francis, J B Allen, D E Mizel, J E Albina, Q W Xie, C F Nathan, S M Wahl

J Exp Med (1993) 178 (2): 749–754.

https://doi.org/10.1084/jem.178.2.749

Published: 01 August 1993

View article titled, Suppression of arthritis by an inhibitor of nitric oxide synthase.

Journal Articles

Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide.

N S Kwon, D J Stuehr, C F Nathan

J Exp Med (1991) 174 (4): 761–767.

https://doi.org/10.1084/jem.174.4.761

Published: 01 October 1991

View article titled, Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide.

Journal Articles

Downregulation of tumor necrosis factor receptors on macrophages and endothelial cells by microtubule depolymerizing agents.

A H Ding, F Porteu, E Sanchez, C F Nathan

J Exp Med (1990) 171 (3): 715–727.

https://doi.org/10.1084/jem.171.3.715

Published: 01 March 1990

View article titled, Downregulation of tumor necrosis factor receptors on macrophages and endothelial cells by microtubule depolymerizing agents.

Journal Articles

Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells.

D J Stuehr, C F Nathan

J Exp Med (1989) 169 (5): 1543–1555.

https://doi.org/10.1084/jem.169.5.1543

Published: 01 May 1989

View article titled, Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells.

Journal Articles

Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide.

D J Stuehr, S S Gross, I Sakuma, R Levi, C F Nathan

J Exp Med (1989) 169 (3): 1011–1020.

https://doi.org/10.1084/jem.169.3.1011

Published: 01 March 1989

View article titled, Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide.

Journal Articles

Agonist and antagonist effects of interferon alpha and beta on activation of human macrophages. Two classes of interferon gamma receptors and blockade of the high-affinity sites by interferon alpha or beta.

R Yoshida, H W Murray, C F Nathan

J Exp Med (1988) 167 (3): 1171–1185.

https://doi.org/10.1084/jem.167.3.1171

Published: 01 March 1988

View article titled, Agonist and antagonist effects of interferon alpha and beta on activation of human macrophages. Two classes of interferon gamma receptors and blockade of the high-affinity sites by interferon alpha or beta.

Journal Articles

Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties.

S D Wolpe, G Davatelis, B Sherry, B Beutler, D G Hesse, H T Nguyen, L L Moldawer, C F Nathan, S F Lowry, A Cerami

J Exp Med (1988) 167 (2): 570–581.

https://doi.org/10.1084/jem.167.2.570

Published: 01 February 1988

View article titled, Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties.

Journal Articles

Recombinant granulocyte/macrophage colony-stimulating factor activates macrophages to inhibit Trypanosoma cruzi and release hydrogen peroxide. Comparison with interferon gamma.

S G Reed, C F Nathan, D L Pihl, P Rodricks, K Shanebeck, P J Conlon, K H Grabstein

J Exp Med (1987) 166 (6): 1734–1746.

https://doi.org/10.1084/jem.166.6.1734

Published: 01 December 1987

View article titled, Recombinant granulocyte/macrophage colony-stimulating factor activates macrophages to inhibit Trypanosoma cruzi and release hydrogen peroxide. Comparison with interferon gamma.

Journal Articles

Secretion of pyruvate. An antioxidant defense of mammalian cells.

J O'Donnell-Tormey, C F Nathan, K Lanks, C J DeBoer, J de la Harpe

J Exp Med (1987) 165 (2): 500–514.

https://doi.org/10.1084/jem.165.2.500

Published: 01 February 1987

View article titled, Secretion of pyruvate. An antioxidant defense of mammalian cells.

Journal Articles

Subcellular location and properties of bactericidal factors from human neutrophils.

J E Gabay, J M Heiple, Z A Cohn, C F Nathan

J Exp Med (1986) 164 (5): 1407–1421.

https://doi.org/10.1084/jem.164.5.1407

Published: 01 November 1986

View article titled, Subcellular location and properties of bactericidal factors from human neutrophils.

Journal Articles

Macrophage deactivation. Altered kinetic properties of superoxide-producing enzyme after exposure to tumor cell-conditioned medium.

S Tsunawaki, C F Nathan

J Exp Med (1986) 164 (4): 1319–1331.

https://doi.org/10.1084/jem.164.4.1319

Published: 01 October 1986

View article titled, Macrophage deactivation. Altered kinetic properties of superoxide-producing enzyme after exposure to tumor cell-conditioned medium.

Journal Articles

Liver macrophages in murine listeriosis. Cell-mediated immunity is correlated with an influx of macrophages capable of generating reactive oxygen intermediates.

D A Lepay, R M Steinman, C F Nathan, H W Murray, Z A Cohn

J Exp Med (1985) 161 (6): 1503–1512.

https://doi.org/10.1084/jem.161.6.1503

Published: 01 June 1985

View article titled, Liver macrophages in murine listeriosis. Cell-mediated immunity is correlated with an influx of macrophages capable of generating reactive oxygen intermediates.

Journal Articles

Murine Kupffer cells. Mononuclear phagocytes deficient in the generation of reactive oxygen intermediates.

D A Lepay, C F Nathan, R M Steinman, H W Murray, Z A Cohn

J Exp Med (1985) 161 (5): 1079–1096.

https://doi.org/10.1084/jem.161.5.1079

Published: 01 May 1985

View article titled, Murine Kupffer cells. Mononuclear phagocytes deficient in the generation of reactive oxygen intermediates.

Journal Articles

Activation of human macrophages. Comparison of other cytokines with interferon-gamma.

C F Nathan, T J Prendergast, M E Wiebe, E R Stanley, E Platzer, H G Remold, K Welte, B Y Rubin, H W Murray

J Exp Med (1984) 160 (2): 600–605.

https://doi.org/10.1084/jem.160.2.600

Published: 01 August 1984

View article titled, Activation of human macrophages. Comparison of other cytokines with interferon-gamma.

Journal Articles

Bacillus Calmette-Guérin-activated murine macrophages kill syngeneic melanoma cells under strict anaerobic conditions.

V H Freedman, T E Gorrell, C F Nathan, C S Copeland, S C Silverstein

J Exp Med (1984) 160 (1): 94–107.

https://doi.org/10.1084/jem.160.1.94

Published: 01 July 1984

View article titled, Bacillus Calmette-Guérin-activated murine macrophages kill syngeneic melanoma cells under strict anaerobic conditions.

Journal Articles

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.

C F Nathan, H W Murray, M E Wiebe, B Y Rubin

J Exp Med (1983) 158 (3): 670–689.

https://doi.org/10.1084/jem.158.3.670

Published: 01 September 1983

View article titled, Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.

Journal Articles

Suppression of macrophage oxidative metabolism by products of malignant and nonmalignant cells.

A Szuro-Sudol, C F Nathan

J Exp Med (1982) 156 (4): 945–961.

https://doi.org/10.1084/jem.156.4.945

Published: 01 October 1982

View article titled, Suppression of macrophage oxidative metabolism by products of malignant and nonmalignant cells.

Journal Articles

Macrophage oxygen-dependent antimicrobial activity. IV. Role of endogenous scavengers of oxygen intermediates.

H W Murray, C F Nathan, Z A Cohn

J Exp Med (1980) 152 (6): 1610–1624.

https://doi.org/10.1084/jem.152.6.1610

Published: 01 December 1980

View article titled, Macrophage oxygen-dependent antimicrobial activity. IV. Role of endogenous scavengers of oxygen intermediates.

Journal Articles

Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates.

H W Murray, C W Juangbhanich, C F Nathan, Z A Cohn

J Exp Med (1979) 150 (4): 950–964.

https://doi.org/10.1084/jem.150.4.950

Published: 01 October 1979

View article titled, Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates.

Journal Articles

Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide.

C F Nathan, L H Brukner, S C Silverstein, Z A Cohn

J Exp Med (1979) 149 (1): 84–99.

https://doi.org/10.1084/jem.149.1.84

Published: 01 January 1979

View article titled, Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide.

NARROW

Suppression of arthritis by an inhibitor of nitric oxide synthase.

Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide.

Downregulation of tumor necrosis factor receptors on macrophages and endothelial cells by microtubule depolymerizing agents.

Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells.

Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide.

Agonist and antagonist effects of interferon alpha and beta on activation of human macrophages. Two classes of interferon gamma receptors and blockade of the high-affinity sites by interferon alpha or beta.

Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties.

Recombinant granulocyte/macrophage colony-stimulating factor activates macrophages to inhibit Trypanosoma cruzi and release hydrogen peroxide. Comparison with interferon gamma.

Secretion of pyruvate. An antioxidant defense of mammalian cells.

Subcellular location and properties of bactericidal factors from human neutrophils.

Macrophage deactivation. Altered kinetic properties of superoxide-producing enzyme after exposure to tumor cell-conditioned medium.

Liver macrophages in murine listeriosis. Cell-mediated immunity is correlated with an influx of macrophages capable of generating reactive oxygen intermediates.

Murine Kupffer cells. Mononuclear phagocytes deficient in the generation of reactive oxygen intermediates.

Activation of human macrophages. Comparison of other cytokines with interferon-gamma.

Bacillus Calmette-Guérin-activated murine macrophages kill syngeneic melanoma cells under strict anaerobic conditions.

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.

Suppression of macrophage oxidative metabolism by products of malignant and nonmalignant cells.

Macrophage oxygen-dependent antimicrobial activity. IV. Role of endogenous scavengers of oxygen intermediates.

Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates.

Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide.

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