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B Beutler
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Journal Articles

Extinction of the tumor necrosis factor locus, and of genes encoding the lipopolysaccharide signaling pathway.

V Kruys, P Thompson, B Beutler
Journal: Journal of Experimental Medicine
J Exp Med (1993) 177 (5): 1383–1390.
https://doi.org/10.1084/jem.177.5.1383
Published: 01 May 1993
View article titled, Extinction of the tumor necrosis factor locus, and of genes encoding the lipopolysaccharide signaling pathway.
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Journal Articles

A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity.

K Peppel, D Crawford, B Beutler
Journal: Journal of Experimental Medicine
J Exp Med (1991) 174 (6): 1483–1489.
https://doi.org/10.1084/jem.174.6.1483
Published: 01 December 1991
View article titled, A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity.
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Journal Articles

Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway.

J Han, P Thompson, B Beutler
Journal: Journal of Experimental Medicine
J Exp Med (1990) 172 (1): 391–394.
https://doi.org/10.1084/jem.172.1.391
Published: 01 July 1990
View article titled, Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway.
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Journal Articles

Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level.

J Han, T Brown, B Beutler
Journal: Journal of Experimental Medicine
J Exp Med (1990) 171 (2): 465–475.
https://doi.org/10.1084/jem.171.2.465
Published: 01 February 1990
View article titled, Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level.
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Journal Articles

Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation.

K J Tracey, H Wei, K R Manogue, Y Fong, D G Hesse, H T Nguyen, G C Kuo, B Beutler, R S Cotran, A Cerami
Journal: Journal of Experimental Medicine
J Exp Med (1988) 167 (3): 1211–1227.
https://doi.org/10.1084/jem.167.3.1211
Published: 01 March 1988
View article titled, Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation.
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Journal Articles

Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties.

S D Wolpe, G Davatelis, B Sherry, B Beutler, D G Hesse, H T Nguyen, L L Moldawer, C F Nathan, S F Lowry, A Cerami
Journal: Journal of Experimental Medicine
J Exp Med (1988) 167 (2): 570–581.
https://doi.org/10.1084/jem.167.2.570
Published: 01 February 1988
View article titled, Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties.
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Journal Articles

Effect of gamma interferon on cachectin expression by mononuclear phagocytes. Reversal of the lpsd (endotoxin resistance) phenotype.

B Beutler, V Tkacenko, I Milsark, N Krochin, A Cerami
Journal: Journal of Experimental Medicine
J Exp Med (1986) 164 (5): 1791–1796.
https://doi.org/10.1084/jem.164.5.1791
Published: 01 November 1986
View article titled, Effect of gamma interferon on cachectin expression by mononuclear phagocytes. Reversal of the lpsd (endotoxin resistance) phenotype.
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Journal Articles

Cachectin/tumor necrosis factor mediates changes of skeletal muscle plasma membrane potential.

K J Tracey, S F Lowry, B Beutler, A Cerami, J D Albert, G T Shires
Journal: Journal of Experimental Medicine
J Exp Med (1986) 164 (4): 1368–1373.
https://doi.org/10.1084/jem.164.4.1368
Published: 01 October 1986
View article titled, Cachectin/tumor necrosis factor mediates changes of skeletal muscle plasma membrane potential.
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Journal Articles

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

C A Dinarello, J G Cannon, S M Wolff, H A Bernheim, B Beutler, A Cerami, I S Figari, M A Palladino, Jr, J V O'Connor
Journal: Journal of Experimental Medicine
J Exp Med (1986) 163 (6): 1433–1450.
https://doi.org/10.1084/jem.163.6.1433
Published: 01 June 1986
View article titled, Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.
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Journal Articles

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.

J M Dayer, B Beutler, A Cerami
Journal: Journal of Experimental Medicine
J Exp Med (1985) 162 (6): 2163–2168.
https://doi.org/10.1084/jem.162.6.2163
Published: 01 December 1985
View article titled, Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.
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Journal Articles

Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells.

B Beutler, J Mahoney, N Le Trang, P Pekala, A Cerami
Journal: Journal of Experimental Medicine
J Exp Med (1985) 161 (5): 984–995.
https://doi.org/10.1084/jem.161.5.984
Published: 01 May 1985
View article titled, Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells.
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