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In This Issue

Oncoprotein hides tumor

Kendall Powell
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Double-edged Gadd45

Kendall Powell
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Antiinflammatory eggs

Kendall Powell
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Toll-free autoimmunity

Kendall Powell
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A plague of deubiquitination

Kendall Powell
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From the Archive

How Heidelberger and Avery sweetened immunology

Heather L. Van Epps
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Meeting Review

Humanized mice : are we there yet?

Francesca Macchiarini,Markus G. Manz,A. Karolina Palucka,Leonard D. Shultz
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Commentary

The many roads to cross-presentation

Tom A.M. Groothuis,Jacques Neefjes
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Brief Definitive Report

Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity

Philip Smith,Rosie E. Fallon,Niamh E. Mangan,Caitriona M. Walsh,Margarida Saraiva,Jon R. Sayers,Andrew N.J. McKenzie,Antonio Alcami,Padraic G. Fallon
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Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-κB activation

Honglin Zhou,Denise M. Monack,Nobuhiko Kayagaki,Ingrid Wertz,Jianpin Yin,Beni Wolf,Vishva M. Dixit
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Article

Toll-like receptor–independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation

Yasutaka Okabe,Kohki Kawane,Shizuo Akira,Tadatsugu Taniguchi,Shigekazu Nagata
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Gadd45β and Gadd45γ are critical for regulating autoimmunity

Lin Liu,Elise Tran,Yani Zhao,Yuchen Huang,Richard Flavell,Binfeng Lu
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Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses

David A. Price,Jason M. Brenchley,Laura E. Ruff,Michael R. Betts,Brenna J. Hill,Mario Roederer,Richard A. Koup,Steven A. Migueles,Emma Gostick,Linda Wooldridge,Andrew K. Sewell,Mark Connors,Daniel C. Douek
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BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway

Andrew Craxton,Kevin E. Draves,Adriana Gruppi,Edward A. Clark
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Sequential development of interleukin 2–dependent effector and regulatory T cells in response to endogenous systemic antigen

Birgit Knoechel,Jens Lohr,Estelle Kahn,Jeffrey A. Bluestone,Abul K. Abbas
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Where CD4+CD25+ T reg cells impinge on autoimmune diabetes

Zhibin Chen,Ann E. Herman,Michael Matos,Diane Mathis,Christophe Benoist
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Coordinated oncogenic transformation and inhibition of host immune responses by the PAX3-FKHR fusion oncoprotein

Stephen Nabarro,Nourredine Himoudi,Antigoni Papanastasiou,Kimberly Gilmour,Sian Gibson,Neil Sebire,Adrian Thrasher,Michael P. Blundell,Mike Hubank,Glenda Canderan,John Anderson
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PU.1 is not strictly required for B cell development and its absence induces a B-2 to B-1 cell switch

Min Ye,Olga Ermakova,Thomas Graf
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PKCβ regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1

Hisaaki Shinohara,Tomoharu Yasuda,Yuichi Aiba,Hideki Sanjo,Megumi Hamadate,Hiroshi Watarai,Hiroaki Sakurai,Tomohiro Kurosaki
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Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung

Godelieve J. de Bree,Ester M.M. van Leeuwen,Theo A. Out,Henk M. Jansen,René E. Jonkers,René A.W. van Lier
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The very 5′ end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions

Simonne Longerich,Atsushi Tanaka,Grazyna Bozek,Dan Nicolae,Ursula Storb
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