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Distinct Mutations in IRAK-4 Confer Hyporesponsiveness to Lipopolysaccharide and Interleukin-1 in a Patient with Recurrent Bacterial Infections

Andrei E. Medvedev,Arnd Lentschat,Douglas B. Kuhns,Jorge C.G. Blanco,Cindy Salkowski,Shuling Zhang,Moshe Arditi,John I. Gallin,Stefanie N. Vogel
View Articletitled, Distinct Mutations in <em>IRAK-4</em> Confer Hyporesponsiveness to Lipopolysaccharide and Interleukin-1 in a Patient with Recurrent Bacterial Infections

Prostaglandin D2 Reinforces Th2 Type Inflammatory Responses of Airways to Low-dose Antigen through Bronchial Expression of Macrophage-derived Chemokine

Kyoko Honda,Masafumi Arima,Gang Cheng,Shinsuke Taki,Hirokuni Hirata,Fukiko Eda,Fumiya Fukushima,Bunpei Yamaguchi,Masahiko Hatano,Takeshi Tokuhisa,Takeshi Fukuda
View Articletitled, Prostaglandin D<sub>2</sub> Reinforces Th2 Type Inflammatory Responses of Airways to Low-dose Antigen through Bronchial Expression of Macrophage-derived Chemokine

Brucella Evades Macrophage Killing via VirB-dependent Sustained Interactions with the Endoplasmic Reticulum

Jean Celli,Chantal de Chastellier,Don-Marc Franchini,Javier Pizarro-Cerda,Edgardo Moreno,Jean-Pierre Gorvel
View Articletitled, <em>Brucella</em> Evades Macrophage Killing via VirB-dependent Sustained Interactions with the Endoplasmic Reticulum

Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule

Cristina Bottino,Roberta Castriconi,Daniela Pende,Paola Rivera,Marina Nanni,Barbara Carnemolla,Claudia Cantoni,Jessica Grassi,Stefania Marcenaro,Nicolas Reymond,Massimo Vitale,Lorenzo Moretta,Marc Lopez,Alessandro Moretta
View Articletitled, Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule

Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8+ T Cells

Willem W. Overwijk,Marc R. Theoret,Steven E. Finkelstein,Deborah R. Surman,Laurina A. de Jong,Florry A. Vyth-Dreese,Trees A. Dellemijn,Paul A. Antony,Paul J. Spiess,Douglas C. Palmer,David M. Heimann,Christopher A. Klebanoff,Zhiya Yu,Leroy N. Hwang,Lionel Feigenbaum,Ada M. Kruisbeek,Steven A. Rosenberg,Nicholas P. Restifo
View Articletitled, Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8<sup>+</sup> T Cells

Coupling Between B Cell Receptor and Phospholipase C-γ2 Is Essential for Mature B Cell Development

Masaki Hikida,Sachiko Johmura,Ari Hashimoto,Mayuko Takezaki,Tomohiro Kurosaki
View Articletitled, Coupling Between B Cell Receptor and Phospholipase C-γ2 Is Essential for Mature B Cell Development

The B Cell Receptor Itself Can Activate Complement to Provide the Complement Receptor 1/2 Ligand Required to Enhance B Cell Immune Responses In Vivo

Joerg Rossbacher,Mark J. Shlomchik
View Articletitled, The B Cell Receptor Itself Can Activate Complement to Provide the Complement Receptor 1/2 Ligand Required to Enhance B Cell Immune Responses In Vivo

Arf6 and Phosphoinositol-4-Phosphate-5-Kinase Activities Permit Bypass of the Rac1 Requirement for β1 Integrin–mediated Bacterial Uptake

Ka-Wing Wong,Ralph R. Isberg
View Articletitled, Arf6 and Phosphoinositol-4-Phosphate-5-Kinase Activities Permit Bypass of the Rac1 Requirement for β<sub>1</sub> Integrin–mediated Bacterial Uptake

Regulation of Dendritic Cell Migration to the Draining Lymph Node : Impact on T Lymphocyte Traffic and Priming

Alfonso Martín-Fontecha,Silvia Sebastiani,Uta E. Höpken,Mariagrazia Uguccioni,Martin Lipp,Antonio Lanzavecchia,Federica Sallusto
View Articletitled, Regulation of Dendritic Cell Migration to the Draining Lymph Node <span class="subtitle-colon">: </span><span class="subtitle">Impact on T Lymphocyte Traffic and Priming </span>

Retinoids Regulate Survival and Antigen Presentation by Immature Dendritic Cells

Frédéric Geissmann,Patrick Revy,Nicole Brousse,Yves Lepelletier,Claudia Folli,Anne Durandy,Pierre Chambon,Michel Dy
View Articletitled, Retinoids Regulate Survival and Antigen Presentation by Immature Dendritic Cells

129-derived Strains of Mice Are Deficient in DNA Polymerase ι and Have Normal Immunoglobulin Hypermutation

John P. McDonald,Ekaterina G. Frank,Brian S. Plosky,Igor B. Rogozin,Chikahide Masutani,Fumio Hanaoka,Roger Woodgate,Patricia J. Gearhart
View Articletitled, 129-derived Strains of Mice Are Deficient in DNA Polymerase ι and Have Normal Immunoglobulin Hypermutation

Brief Definitive Report

Impaired Differentiation of Osteoclasts in TREM-2–deficient Individuals

Marina Cella,Cecilia Buonsanti,Carey Strader,Takayuki Kondo,Andrea Salmaggi,Marco Colonna
View Articletitled, Impaired Differentiation of Osteoclasts in TREM-2–deficient Individuals

Tuberculosis Toxin Blocking Phagosome Maturation Inhibits a Novel Ca2+/Calmodulin-PI3K hVPS34 Cascade

Isabelle Vergne,Jennifer Chua,Vojo Deretic
View Articletitled, Tuberculosis Toxin Blocking Phagosome Maturation Inhibits a Novel Ca<sup>2+</sup>/Calmodulin-PI3K hVPS34 Cascade

A Role of the Fast ATP-gated P2X1 Cation Channel in Thrombosis of Small Arteries In Vivo

Béatrice Hechler,Nadège Lenain,Patrizia Marchese,Catherine Vial,Véronique Heim,Monique Freund,Jean-Pierre Cazenave,Marco Cattaneo,Zaverio M. Ruggeri,Richard Evans,Christian Gachet
View Articletitled, A Role of the Fast ATP-gated P2X<sub>1</sub> Cation Channel in Thrombosis of Small Arteries In Vivo

DAP12/TREM2 Deficiency Results in Impaired Osteoclast Differentiation and Osteoporotic Features

Juha Paloneva,Jami Mandelin,Anna Kiialainen,Tom Böhling,Johannes Prudlo,Panu Hakola,Matti Haltia,Yrjö T. Konttinen,Leena Peltonen
View Articletitled, DAP12/TREM2 Deficiency Results in Impaired Osteoclast Differentiation and Osteoporotic Features

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