Page 1 | Search Results | Journal of Experimental Medicine

Skip Nav Destination

1-12 of 12

Sort by

Sort Order Select

Journal Articles

DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes

Robert W. Maul, Thomas MacCarthy, Ekaterina G. Frank, Katherine A. Donigan, Mary P. McLenigan, William Yang, Huseyin Saribasak, Donald E. Huston, Sabine S. Lange, Roger Woodgate, Patricia J. Gearhart

J Exp Med (2016) 213 (9): 1675–1683.

https://doi.org/10.1084/jem.20151227

Published: 25 July 2016

View article titled, DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes

Includes: Supplementary data

Journal Articles

Spt5 accumulation at variable genes distinguishes somatic hypermutation in germinal center B cells from ex vivo–activated cells

Robert W. Maul, Zheng Cao, Lakshmi Venkataraman, Carol A. Giorgetti, Joan L. Press, Yves Denizot, Hansen Du, Ranjan Sen, Patricia J. Gearhart

J Exp Med (2014) 211 (11): 2297–2306.

https://doi.org/10.1084/jem.20131512

Published: 06 October 2014

View article titled, Spt5 accumulation at variable genes distinguishes somatic hypermutation in germinal center B cells from ex vivo–activated cells

Includes: Supplementary data

Journal Articles

DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions

Huseyin Saribasak, Robert W. Maul, Zheng Cao, William W. Yang, Dominik Schenten, Sven Kracker, Patricia J. Gearhart

J Exp Med (2012) 209 (6): 1075–1081.

https://doi.org/10.1084/jem.20112234

Published: 21 May 2012

View article titled, DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions

Includes: Supplementary data

Journal Articles

XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in Igh genes

Huseyin Saribasak, Robert W. Maul, Zheng Cao, Rhonda L. McClure, William Yang, Daniel R. McNeill, David M. Wilson, III, Patricia J. Gearhart

J Exp Med (2011) 208 (11): 2209–2216.

https://doi.org/10.1084/jem.20111135

Published: 03 October 2011

View article titled, XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in <em>Igh</em> genes

Includes: Supplementary data

Journal Articles

Immunoglobulin switch μ sequence causes RNA polymerase II accumulation and reduces dA hypermutation

Deepa Rajagopal, Robert W. Maul, Amalendu Ghosh, Tirtha Chakraborty, Ahmed Amine Khamlichi, Ranjan Sen, Patricia J. Gearhart

J Exp Med (2009) 206 (6): 1237–1244.

https://doi.org/10.1084/jem.20082514

Published: 11 May 2009

View article titled, Immunoglobulin switch μ sequence causes RNA polymerase II accumulation and reduces dA hypermutation

Includes: Supplementary data

Journal Articles

Women, autoimmunity, and cancer: a dangerous liaison between estrogen and activation-induced deaminase?

Robert W. Maul, Patricia J. Gearhart

J Exp Med (2009) 206 (1): 11–13.

https://doi.org/10.1084/jem.20080086

Published: 12 January 2009

View article titled, Women, autoimmunity, and cancer: a dangerous liaison between estrogen and activation-induced deaminase?

Journal Articles

MSH2–MSH6 stimulates DNA polymerase η, suggesting a role for A:T mutations in antibody genes

Teresa M. Wilson, Alexandra Vaisman, Stella A. Martomo, Patsa Sullivan, Li Lan, Fumio Hanaoka, Akira Yasui, Roger Woodgate, Patricia J. Gearhart

J Exp Med (2005) 201 (4): 637–645.

https://doi.org/10.1084/jem.20042066

Published: 14 February 2005

View article titled, MSH2–MSH6 stimulates DNA polymerase η, suggesting a role for A:T mutations in antibody genes

Journal Articles

Immunoglobulin Class Switch Recombination Is Impaired in Atm-deficient Mice

Joanne M. Lumsden, Thomas McCarty, Lisa K. Petiniot, Rhuna Shen, Carrolee Barlow, Thomas A. Wynn, Herbert C. Morse, III, Patricia J. Gearhart, Anthony Wynshaw-Boris, Edward E. Max, Richard J. Hodes

J Exp Med (2004) 200 (9): 1111–1121.

https://doi.org/10.1084/jem.20041074

Published: 25 October 2004

View article titled, Immunoglobulin Class Switch Recombination Is Impaired in <em>Atm</em>-deficient Mice

Journal Articles

A Role for Msh6 But Not Msh3 in Somatic Hypermutation and Class Switch Recombination

Stella A. Martomo, William W. Yang, Patricia J. Gearhart

J Exp Med (2004) 200 (1): 61–68.

https://doi.org/10.1084/jem.20040691

Published: 06 July 2004

View article titled, A Role for Msh6 But Not Msh3 in Somatic Hypermutation and Class Switch Recombination

Includes: Supplementary data

Journal Articles

Absence of DNA Polymerase η Reveals Targeting of C Mutations on the Nontranscribed Strand in Immunoglobulin Switch Regions

Xianmin Zeng, George A. Negrete, Cynthia Kasmer, William W. Yang, Patricia J. Gearhart

J Exp Med (2004) 199 (7): 917–924.

https://doi.org/10.1084/jem.20032022

Published: 29 March 2004

View article titled, Absence of DNA Polymerase η Reveals Targeting of C Mutations on the Nontranscribed Strand in Immunoglobulin Switch Regions

Includes: Supplementary data

Journal Articles

129-derived Strains of Mice Are Deficient in DNA Polymerase ι and Have Normal Immunoglobulin Hypermutation

John P. McDonald, Ekaterina G. Frank, Brian S. Plosky, Igor B. Rogozin, Chikahide Masutani, Fumio Hanaoka, Roger Woodgate, Patricia J. Gearhart

J Exp Med (2003) 198 (4): 635–643.

https://doi.org/10.1084/jem.20030767

Published: 18 August 2003

View article titled, 129-derived Strains of Mice Are Deficient in DNA Polymerase ι and Have Normal Immunoglobulin Hypermutation

Journal Articles

Increased Hypermutation at G and C Nucleotides in Immunoglobulin Variable Genes from Mice Deficient in the MSH2 Mismatch Repair Protein

Quy H. Phung, David B. Winter, Aaron Cranston, Robert E. Tarone, Vilhelm A. Bohr, Richard Fishel, Patricia J. Gearhart

J Exp Med (1998) 187 (11): 1745–1751.

https://doi.org/10.1084/jem.187.11.1745

Published: 01 June 1998

View article titled, Increased Hypermutation at G and C Nucleotides in Immunoglobulin Variable Genes from Mice Deficient in the MSH2 Mismatch Repair Protein

NARROW

DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes

Spt5 accumulation at variable genes distinguishes somatic hypermutation in germinal center B cells from ex vivo–activated cells

DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions

XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in Igh genes

Immunoglobulin switch μ sequence causes RNA polymerase II accumulation and reduces dA hypermutation

Women, autoimmunity, and cancer: a dangerous liaison between estrogen and activation-induced deaminase?

MSH2–MSH6 stimulates DNA polymerase η, suggesting a role for A:T mutations in antibody genes

Immunoglobulin Class Switch Recombination Is Impaired in Atm-deficient Mice

A Role for Msh6 But Not Msh3 in Somatic Hypermutation and Class Switch Recombination

Absence of DNA Polymerase η Reveals Targeting of C Mutations on the Nontranscribed Strand in Immunoglobulin Switch Regions

129-derived Strains of Mice Are Deficient in DNA Polymerase ι and Have Normal Immunoglobulin Hypermutation

Increased Hypermutation at G and C Nucleotides in Immunoglobulin Variable Genes from Mice Deficient in the MSH2 Mismatch Repair Protein

Email alerts

Email alerts

This Feature Is Available To Subscribers Only