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2 July 2001
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Natural killer (NK) cells expressing NK receptors Ly49C, I, and H were depleted in vivo from murine cytomegalovirus (MCMV)-infected C57BL/6 mice with monoclonal antibody (mAb) 1F8. This resulted in increased viral titers and pathology during an acute MCMV infection (day 4). Hematoxylin and eosin staining of mAb 1F8-treated C57BL/6 mouse livers (bottom panel) shows the presence of large necrotic areas, in contrast to discrete loci of inflammation as seen in MCMV-infected livers from mice not depleted of NK cells (top panel). See related article in this issue by Daniels et al.,pp. 29-44 - PDF Icon PDF LinkTable of Contents
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ISSN 0022-1007
EISSN 1540-9538
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Article
Discrete Cleavage Motifs of Constitutive and Immunoproteasomes Revealed by Quantitative Analysis of Cleavage Products
R.E.M. Toes,A.K. Nussbaum,S. Degermann,M. Schirle,N.P.N. Emmerich,M. Kraft,C. Laplace,A. Zwinderman,T.P. Dick,J. Müller,B. Schönfisch,C. Schmid,H.-J. Fehling,S. Stevanovic,H.G. Rammensee,H. Schild
Hyperactivation of P21ras and the Hematopoietic-Specific Rho Gtpase, Rac2, Cooperate to Alter the Proliferation of Neurofibromin-Deficient Mast Cells in Vivo and in Vitro
David A. Ingram,Kelly Hiatt,Alastair J. King,Lucy Fisher,Rama Shivakumar,Christina Derstine,Mary Jo Wenning,Bruce Diaz,Jeffrey B. Travers,Antoinette Hood,Mark Marshall,David A. Williams,D. Wade Clapp
Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line: A Point Mutation in a Conserved Region of Md-2 Abolishes Endotoxin-Induced Signaling
Andra B. Schromm,Egil Lien,Philipp Henneke,Jesse C. Chow,Atsutoshi Yoshimura,Holger Heine,Eicke Latz,Brian G. Monks,David A. Schwartz,Kensuke Miyake,Douglas T. Golenbock
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