Issues

Commentary

The Promotion of  V Region Hypermutation

Matthew D. Scharff,Vladimir Poltoratsky,Nancy S. Green
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Article

The Common Cytokine Receptor γ Chain Plays an Essential Role in Regulating Lymphoid Homeostasis

Hiroshi Nakajima,Elizabeth W. Shores,Masayuki Noguchi,Warren J. Leonard
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Peripheral Expression of Jak3 Is Required to Maintain T Lymphocyte Function

Daniel C. Thomis,Leslie J. Berg
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Absence of Respiratory Burst in X-linked Chronic Granulomatous Disease Mice Leads to Abnormalities in Both Host Defense and Inflammatory Response to Aspergillus fumigatus

David E. Morgenstern,Mary A.C. Gifford,Ling Lin Li,Claire M. Doerschuk,Mary C. Dinauer
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The Efficiency of CD4 Recruitment to Ligand-engaged TCR Controls the Agonist/Partial Agonist Properties of Peptide–MHC Molecule Ligands

Joaquín Madrenas,Luan A. Chau,Judy Smith,Jeffrey A. Bluestone,Ronald N. Germain
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Reduced Incidence and Severity of Antigen-induced Autoimmune Diseases in Mice Lacking Interferon Regulatory Factor-1

Yoshifumi Tada,Alexandra Ho,Toshifumi Matsuyama,Tak W. Mak
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The Transcriptional Promoter Regulates Hypermutation of the Antibody Heavy Chain Locus

Kathleen Tumas-Brundage,Tim Manser
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Distinct Costimulatory Molecules Are Required for the Induction of Effector and Memory Cytotoxic T Lymphocytes

Yang Liu,Roland H. Wenger,Min Zhao,Peter J. Nielsen
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Negative Selection in the Thymus Includes Semimature T Cells

Hidehiro Kishimoto,Jonathan Sprent
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Estrogen Protects Lenses against Cataract Induced by Transforming Growth Factor-β (TGFβ)

Angela M. Hales,Coral G. Chamberlain,Christopher R. Murphy,John W. McAvoy
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rho, a Small GTP-Binding Protein, Is Essential for Shigella Invasion of Epithelial Cells

Masahisa Watarai,Yoichi Kamata,Shunji Kozaki,Chihiro Sasakawa
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HIV-1 Induces Cytotoxic T Lymphocytes in the Cervix of Infected Women

Luwy Musey,Yuxiang Hu,Linda Eckert,Michael Christensen,Tobi Karchmer,M. Juliana McElrath
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Major Histocompatibility Complex (MHC) Class I Gene Expression in Single Neurons of the Central Nervous System: Differential Regulation by Interferon (IFN)-γ and Tumor Necrosis Factor (TNF)-α

H. Neumann,H. Schmidt,A. Cavalié,D. Jenne,H. Wekerle
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Maturation Stages of Mouse Dendritic Cells in Growth Factor–dependent Long-Term Cultures

Claudia Winzler,Patrizia Rovere,Maria Rescigno,Francesca Granucci,Giuseppe Penna,Luciano Adorini,Valerie S. Zimmermann,Jean Davoust,Paola Ricciardi-Castagnoli
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Constitutive Expression of Interleukin (IL)-4 In Vivo Causes Autoimmune-type Disorders in Mice

Klaus J. Erb,Beate Rüger,Maja von Brevern,Bernhard Ryffel,Annelise Schimpl,Karen Rivett
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CD40 Ligation on Human Cord Blood CD34+Hematopoietic Progenitors Induces Their Proliferation and Differentiation into Functional Dendritic Cells

Leopoldo Flores-Romo,Pia Björck,Valérie Duvert,Cees van Kooten,Sem Saeland,Jacques Banchereau
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Brief Definitive Report

Crucial Role of Jak3 in Negative Selection of Self-reactive T Cells

Kaoru Saijo,Seung Yong Park,Yasuo Ishida,Hisashi Arase,Takashi Saito
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Asynchronous Coreceptor Downregulation after Positive Thymic Selection: Prolonged Maintenance of the Double Positive State in CD8 Lineage Differentiation Due to Sustained Biosynthesis of the CD4 Coreceptor

Thomas Barthlott,Hubertus Kohler,Klaus Eichmann
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The HCMV Gene Products US11 and US2 Differ in Their Ability to Attack Allelic Forms of Murine Major Histocompatibility Complex (MHC) Class I Heavy Chains

Robert P. Machold,Emmanuel J.H.J. Wiertz,Thomas R. Jones,H.L. Ploegh
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HLA Class I Binding Motifs Derived from Random Peptide Libraries Differ at the COOH Terminus from Those of Eluted Peptides

Miles P. Davenport,Katherine J. Smith,Dan Barouch,Scott W. Reid,Wanda M. Bodnar,Anthony C. Willis,Donald F. Hunt,Adrian V.S. Hill
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