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20 April 2009
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Chan et al. find a surprising new function for the tyrosine kinase FAK in inhibiting the formation of invadopodia, the membrane protrusions used by cells to degrade their surrounding extracellular matrix. In FAK's absence, its downstream kinase Src redistributes to invadopodia and away from focal adhesions (where warmer colors indicate lower Src activity).
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ISSN 0021-9525
EISSN 1540-8140
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