On the cover
The SCF ubiquitin ligase prevents centriole reduplication by targeting the kinase Plk4 for degradation. Expression of a non-degradable form of Plk4 allows a mother centriole (red) to assemble multiple daughters (colored blocks).
See page 225.
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Nunnari is using cutting-edge microscopy techniques to explore mutations affecting mitochondrial fusion and fission in living cells and whole organisms.