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Starting a tumor off wrong

Mitch Leslie
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Myosins pull together to move cargo

Mitch Leslie
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Pol II piece makes and breaks mRNA

Mitch Leslie
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RhoG welcomes leukocytes

Mitch Leslie
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Going their own way in the NPC

Mitch Leslie
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Research Roundup

Golgi helps shape dendrites

Nicole LeBrasseur
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Independent membrane protein clustering

Nicole LeBrasseur
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Mitochondria move to immune synapse

Nicole LeBrasseur
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Stick with gap junctions

Nicole LeBrasseur
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People & Ideas

Konrad Hochedlinger: The new kid of nuclear reprogramming

Ruth Williams
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Report

Global chromatin compaction limits the strength of the DNA damage response

Matilde Murga,Isabel Jaco,Yuhong Fan,Rebeca Soria,Barbara Martinez-Pastor,Myriam Cuadrado,Seung-Min Yang,Maria A. Blasco,Arthur I. Skoultchi,Oscar Fernandez-Capetillo
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Article

APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice

Christine M. Caldwell,Rebecca A. Green,Kenneth B. Kaplan
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Nuclear mRNA export requires specific FG nucleoporins for translocation through the nuclear pore complex

Laura J. Terry,Susan R. Wente
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The Rpb7p subunit of yeast RNA polymerase II plays roles in the two major cytoplasmic mRNA decay mechanisms

Rona Lotan,Vicky Goler-Baron,Lea Duek,Gal Haimovich,Mordechai Choder
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Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies

Sébastien Durand,Nicolas Cougot,Florence Mahuteau-Betzer,Chi-Hung Nguyen,David S. Grierson,Edouard Bertrand,Jamal Tazi,Fabrice Lejeune
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Tim54p connects inner membrane assembly and proteolytic pathways in the mitochondrion

David K. Hwang,Steven M. Claypool,Danielle Leuenberger,Heather L. Tienson,Carla M. Koehler
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Control of nuclear centration in the C. elegans zygote by receptor-independent Gα signaling and myosin II

Morgan B. Goulding,Julie C. Canman,Eric N. Senning,Andrew H. Marcus,Bruce Bowerman
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Myo4p is a monomeric myosin with motility uniquely adapted to transport mRNA

Brian D. Dunn,Takeshi Sakamoto,Myoung-Soon S. Hong,James R. Sellers,Peter A. Takizawa
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Actin–myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility

Patricia T. Yam,Cyrus A. Wilson,Lin Ji,Benedict Hebert,Erin L. Barnhart,Natalie A. Dye,Paul W. Wiseman,Gaudenz Danuser,Julie A. Theriot
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The protein tyrosine phosphatase Pez regulates TGFβ, epithelial–mesenchymal transition, and organ development

Leila Wyatt,Carol Wadham,Lesley A. Crocker,Michael Lardelli,Yeesim Khew-Goodall
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Proteolysis and membrane capture of F-spondin generates combinatorial guidance cues from a single molecule

Sophie Zisman,Karen Marom,Oshri Avraham,Lilah Rinsky-Halivni,Uri Gai,Gilit Kligun,Vered Tzarfaty-Majar,Tatsuo Suzuki,Avihu Klar
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Cofilin recruitment and function during actin-mediated endocytosis dictated by actin nucleotide state

Voytek Okreglak,David G. Drubin
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The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways

Neal M. Alto,Andrew W. Weflen,Matthew J. Rardin,Defne Yarar,Cheri S. Lazar,Raffi Tonikian,Antonius Koller,Susan S. Taylor,Charles Boone,Sachdev S. Sidhu,Sandra L. Schmid,Gail A. Hecht,Jack E. Dixon
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RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration

Jaap D. van Buul,Michael J. Allingham,Thomas Samson,Julia Meller,Etienne Boulter,Rafael García-Mata,Keith Burridge
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The EphA4 receptor regulates dendritic spine remodeling by affecting β1-integrin signaling pathways

Caroline Bourgin,Keith K. Murai,Melanie Richter,Elena B. Pasquale
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Correction

A role for Rab5 in structuring the endoplasmic reticulum

Anjon Audhya,Arshad Desai,Karen Oegema
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