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In This Issue

Caching killer carbs

Mitch Leslie
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Small cancer cells don't stray

Mitch Leslie
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Splitting the difference on peroxisomes

Mitch Leslie
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Separate and unequal Deltas

Mitch Leslie
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People & Ideas

Howard Hang: Posttranslational pathogenesis

Nicole LeBrasseur
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Spotlight

A reply from HHMI

Tom Cech,Jack Dixon,Avice Meehan,Josie Briggs,Carl Rhodes
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Response from Mike Rossner (Executive Director, The Rockefeller University Press) and Ira Mellman (Editor in Chief, The Journal of Cell Biology):

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Report

Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity

Kerstin H. Thein,Julia Kleylein-Sohn,Erich A. Nigg,Ulrike Gruneberg
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Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity

Karni Schlessinger,Edward J. McManus,Alan Hall
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Functional dissection of Rab GTPases involved in primary cilium formation

Shin-ichiro Yoshimura,Johannes Egerer,Evelyn Fuchs,Alexander K. Haas,Francis A. Barr
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Article

Cyclin E overexpression impairs progression through mitosis by inhibiting APCCdh1

Jamie M. Keck,Matthew K. Summers,Donato Tedesco,Susanna Ekholm-Reed,Li-Chiou Chuang,Peter K. Jackson,Steven I. Reed
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A novel Crumbs3 isoform regulates cell division and ciliogenesis via importin β interactions

Shuling Fan,Vanessa Fogg,Qian Wang,Xiao-Wei Chen,Chia-Jen Liu,Ben Margolis
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Yeast peroxisomes multiply by growth and division

Alison M. Motley,Ewald H. Hettema
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A vesicle surface tyrosine kinase regulates phagosome maturation

Jun Fang,Joseph A. Brzostowski,Stephen Ou,Nilgun Isik,Vinod Nair,Tian Jin
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uPAR induces epithelial–mesenchymal transition in hypoxic breast cancer cells

Robin D. Lester,Minji Jo,Valérie Montel,Shinako Takimoto,Steven L. Gonias
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Cell size and invasion in TGF-β–induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway

Samy Lamouille,Rik Derynck
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An ACAP1-containing clathrin coat complex for endocytic recycling

Jian Li,Peter J. Peters,Ming Bai,Jun Dai,Erik Bos,Tomas Kirchhausen,Konstantin V. Kandror,Victor W. Hsu
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Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo

Insa Geffers,Katrin Serth,Gavin Chapman,Robert Jaekel,Karin Schuster-Gossler,Ralf Cordes,Duncan B. Sparrow,Elisabeth Kremmer,Sally L. Dunwoodie,Thomas Klein,Achim Gossler
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The phosphatase laforin crosses evolutionary boundaries and links carbohydrate metabolism to neuronal disease

Matthew S. Gentry,Robert H. Dowen, III,Carolyn A. Worby,Seema Mattoo,Joseph R. Ecker,Jack E. Dixon
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Facilitation versus depression in cultured hippocampal neurons determined by targeting of Ca2+ channel Cavβ4 versus Cavβ2 subunits to synaptic terminals

Mian Xie,Xiang Li,Jing Han,Daniel L. Vogt,Silke Wittemann,Melanie D. Mark,Stefan Herlitze
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The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42

Marta Rosário,Renate Franke,Christien Bednarski,Walter Birchmeier
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Localized zones of Rho and Rac activities drive initiation and expansion of epithelial cell–cell adhesion

Soichiro Yamada,W. James Nelson
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Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell–cell contacts in mammalian epithelial cells

Madhavi P. Maddugoda,Matthew S. Crampton,Annette M. Shewan,Alpha S. Yap
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