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In This Issue

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Localized Biphasic Changes in Phosphatidylinositol-4,5-Bisphosphate at Sites of Phagocytosis

Roberto J. Botelho,Mary Teruel,Renee Dierckman,Richard Anderson,Alan Wells,John D. York,Tobias Meyer,Sergio Grinstein
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Identification of an Outer Segment Targeting Signal in the Cooh Terminus of Rhodopsin Using Transgenic Xenopus laevis

Beatrice M. Tam,Orson L. Moritz,Lawrence B. Hurd,David S. Papermaster
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P53 Binding Protein 1 (53bp1) Is an Early Participant in the Cellular Response to DNA Double-Strand Breaks

Linda B. Schultz,Nabil H. Chehab,Asra Malikzay,Thanos D. Halazonetis
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Wee1-Regulated Apoptosis Mediated by the Crk Adaptor Protein in Xenopus Egg Extracts

Jesse J. Smith,Erica K. Evans,Monica Murakami,Mary B. Moyer,M. Arthur Moseley,George Vande Woude,Sally Kornbluth
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Skeletor, a Novel Chromosomal Protein That Redistributes during Mitosis Provides Evidence for the Formation of a Spindle Matrix

Diana L. Walker,Dong Wang,Ye Jin,Uttama Rath,Yanming Wang,Jørgen Johansen,Kristen M. Johansen
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Dual Stimulation of Ras/Mitogen-Activated Protein Kinase and Rhoa by Cell Adhesion to Fibronectin Supports Growth Factor–Stimulated Cell Cycle Progression

Erik H.J. Danen,Petra Sonneveld,Arnoud Sonnenberg,Kenneth M. Yamada
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The Plastid of Toxoplasma gondii Is Divided by Association with the Centrosomes

Boris Striepen,Michael J. Crawford,Michael K. Shaw,Lewis G. Tilney,Frank Seeber,David S. Roos
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Actopaxin, a New Focal Adhesion Protein That Binds Paxillin Ld Motifs and Actin and Regulates Cell Adhesion

Sotiris N. Nikolopoulos,Christopher E. Turner
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Temporal and Spatial Distribution of Activated Pak1 in Fibroblasts

Mary Ann Sells,Amanda Pfaff,Jonathan Chernoff
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In Vitro Assembly and Structure of Trichocyte Keratin Intermediate Filaments: A Novel Role for Stabilization by Disulfide Bonding

He Wang,David A.D. Parry,Leslie N. Jones,William W. Idler,Lyuben N. Marekov,Peter M. Steinert
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Metaphase to Anaphase (mat) Transition–Defective Mutants inCaenorhabditis elegans

Andy Golden,Penny L. Sadler,Matthew R. Wallenfang,Jill M. Schumacher,Danielle R. Hamill,Gayle Bates,Bruce Bowerman,Geraldine Seydoux,Diane C. Shakes
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Flightin Is Essential for Thick Filament Assembly and Sarcomere Stability in Drosophila Flight Muscles

Mary C. Reedy,Belinda Bullard,Jim O. Vigoreaux
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Cell Cycle Programs of Gene Expression Control Morphogenetic Protein Localization

Matthew Lord,Melody C. Yang,Michelle Mischke,John Chant
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Characterization and Reconstitution of Drosophila γ-Tubulin Ring Complex Subunits

Ruwanthi N. Gunawardane,Ona C. Martin,Kan Cao,Lijun Zhang,Kimberly Dej,Akihiro Iwamatsu,Yixian Zheng
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The Role of Xgrip210 in γ-Tubulin Ring Complex Assembly and Centrosome Recruitment

Lijun Zhang,Thomas J. Keating,Andrew Wilde,Gary G. Borisy,Yixian Zheng
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Transgenic Activation of Ras in Neurons Promotes Hypertrophy and Protects from Lesion-Induced Degeneration

Rolf Heumann,Christoph Goemans,Daniela Bartsch,Kurt Lingenhöhl,Peter C. Waldmeier,Bastian Hengerer,Peter R. Allegrini,Karl Schellander,Erwin F. Wagner,Thomas Arendt,Rigobert H. Kamdem,Kirstin Obst-Pernberg,Frank Narz,Petra Wahle,Hartmut Berns
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Activated R-Ras, Rac1, Pi 3-Kinase and Pkcε Can Each Restore Cell Spreading Inhibited by Isolated Integrin β1 Cytoplasmic Domains

Allison L. Berrier,Anthony M. Mastrangelo,Julian Downward,Mark Ginsberg,Susan E. LaFlamme
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In Vivo Analysis of Cajal Body Movement, Separation, and Joining in Live Human Cells

Melpomeni Platani,Ilya Goldberg,Jason R. Swedlow,Angus I. Lamond
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Report

Human Survivin Is a Kinetochore-Associated Passenger Protein

Dimitrios A. Skoufias,Cristiana Mollinari,Françoise B. Lacroix,Robert L. Margolis
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Loss of Calpain 3 Proteolytic Activity Leads to Muscular Dystrophy and to Apoptosis-Associated Iκbα/Nuclear Factor κb Pathway Perturbation in Mice

Isabelle Richard,Carinne Roudaut,Sylvie Marchand,Stephen Baghdiguian,Muriel Herasse,Daniel Stockholm,Yasuko Ono,Laurence Suel,Nathalie Bourg,Hiroyuki Sorimachi,Gérard Lefranc,Michel Fardeau,Alain Sébille,Jacques S. Beckmann
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Human Sperm Telomere–Binding Complex Involves Histone H2b and Secures Telomere Membrane Attachment

Arunas A. Gineitis,Irina A. Zalenskaya,Peter M. Yau,E. Morton Bradbury,Andrei O. Zalensky
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