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In This Issue

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In Memoriam

An Award for Cell Biology

Sanford M. Simon
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Review

A First Glimpse at the Structure of the Tom Translocase from the Mitochondrial Outer Membrane

Adriana Verschoor,Trevor Lithgow
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Life without Perlecan Has Its Problems

Bjorn R. Olsen
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Report

Loss of a-Type Lamin Expression Compromises Nuclear Envelope Integrity Leading to Muscular Dystrophy

In Special Collection: JCB65: Nuclear and Chromatin Biology
Teresa Sullivan,Diana Escalante-Alcalde,Harshida Bhatt,Miriam Anver,Narayan Bhat,Kunio Nagashima,Colin L. Stewart,Brian Burke
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Human Ect2 Is an Exchange Factor for Rho Gtpases, Phosphorylated in G2/M Phases, and Involved in Cytokinesis

Takashi Tatsumoto,Xiaozhen Xie,Rayah Blumenthal,Isamu Okamoto,Toru Miki
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Morphological Control of Inositol-1,4,5-Trisphosphate–Dependent Signals

Charles C. Fink,Boris Slepchenko,Ion I. Moraru,James Schaff,James Watras,Leslie M. Loew
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Conservation of a Gliding Motility and Cell Invasion Machinery in Apicomplexan Parasites

Stefan Kappe,Thomas Bruderer,Soren Gantt,Hisashi Fujioka,Victor Nussenzweig,Robert Ménard
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Article

Replication of Tobacco Mosaic Virus on Endoplasmic Reticulum and Role of the Cytoskeleton and Virus Movement Protein in Intracellular Distribution of Viral RNA

Paloma Más,Roger N. Beachy
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The Tom Core Complex: The General Protein Import Pore of the Outer Membrane of Mitochondria

Uwe Ahting,Clemens Thun,Reiner Hegerl,Dieter Typke,Frank E. Nargang,Walter Neupert,Stephan Nussberger
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Centriolar Satellites: Molecular Characterization, Atp-Dependent Movement toward Centrioles and Possible Involvement in Ciliogenesis

Akiharu Kubo,Hiroyuki Sasaki,Akiko Yuba-Kubo,Shoichiro Tsukita,Nobuyuki Shiina
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Cell Cycle–Regulated Attachment of the Ubiquitin-Related Protein Sumo to the Yeast Septins

Erica S. Johnson,Günter Blobel
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Ankyrin-B Is Required for Intracellular Sorting of Structurally Diverse Ca2+ Homeostasis Proteins

Shmuel Tuvia,Mona Buhusi,Lydia Davis,Mary Reedy,Vann Bennett
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Rac Downregulates Rho Activity: Reciprocal Balance between Both Gtpases Determines Cellular Morphology and Migratory Behavior

Eva E. Sander,Jean P. ten Klooster,Sanne van Delft,Rob A. van der Kammen,John G. Collard
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Phosphorylation of Myosin-Binding Subunit (Mbs) of Myosin Phosphatase by Rho-Kinase in Vivo

Yoji Kawano,Yuko Fukata,Noriko Oshiro,Mutsuki Amano,Toshikazu Nakamura,Masaaki Ito,Fumio Matsumura,Masaki Inagaki,Kozo Kaibuchi
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A Structural Model for Phosphorylation Control of Dictyostelium Myosin II Thick Filament Assembly

Wenchuan Liang,Hans M. Warrick,James A. Spudich
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Programmed Cell Death of Embryonic Motoneurons Triggered through the FAS Death Receptor

Cédric Raoul,Christopher E. Henderson,Brigitte Pettmann
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P53 Inhibits α6β4 Integrin Survival Signaling by Promoting the Caspase 3–Dependent Cleavage of Akt/PKB

Robin E. Bachelder,Mark J. Ribick,Alessandra Marchetti,Rita Falcioni,Silvia Soddu,Kathryn R. Davis,Arthur M. Mercurio
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Enhancement of Endothelial Cell Migration and in Vitro Tube Formation by Tap20, a Novel β5 Integrin–Modulating, Pkcθ-Dependent Protein

Shaoqing Tang,Yunling Gao,J. Anthony Ware
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Analysis of the Roles of 14-3-3 in the Platelet Glycoprotein Ib-IX–Mediated Activation of Integrin αIIbβ3 Using a Reconstituted Mammalian Cell Expression Model

Minyi Gu,Xiaodong Xi,Graham D. Englund,Michael C. Berndt,Xiaoping Du
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Matrix Gla Protein Is a Developmental Regulator of Chondrocyte Mineralization And, When Constitutively Expressed, Blocks Endochondral and Intramembranous Ossification in the Limb

Kimitoshi Yagami,Jo-Young Suh,Motomi Enomoto-Iwamoto,Eiki Koyama,William R. Abrams,Irving M. Shapiro,Maurizio Pacifici,Masahiro Iwamoto
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Perlecan Maintains the Integrity of Cartilage and Some Basement Membranes

Mercedes Costell,Erika Gustafsson,Attila Aszódi,Matthias Mörgelin,Wilhelm Bloch,Ernst Hunziker,Klaus Addicks,Rupert Timpl,Reinhard Fässler
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