The dry mass, wet mass, and volume of mitochondria of normal rat liver were determined, as well as nitrogen content and concentration. A scheme of multiple approaches to these quantities was devised, permitting comparison of values obtained by independent methods. The following basic values are considered highly accurate: Mean dry mass, 13.6 x 10-14 g; mean wet mass, 51.8 x 10-14 g; mean volume, 0.43 µ3; nitrogen content, 1.75 x 10-14 g The work emphasizes the fact that in mitochondria the quantities, mass, and volume occur in logarithmic-normal distributions.

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