Using insertional mutagenesis in Chlamydomonas, the authors identified a new mutation in the PF2 locus that causes motility defects. Further analysis showed that PF2 encodes subunit 4 of the DRC. The PF2 protein is uniformly distributed along the length of the axoneme and also associates with the basal body region, and its predicted structure has several coiled-coil domains that could mediate...
The Rockefeller University Press
2003
The Rockefeller University Press
2003
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