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Michael L. Klein
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Journal Articles

A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine

Marina A. Kasimova, Aysenur Torun Yazici, Yevgen Yudin, Daniele Granata, Michael L. Klein, Tibor Rohacs, Vincenzo Carnevale
Journal: Journal of General Physiology
J Gen Physiol (2018) 150 (11): 1554–1566.
https://doi.org/10.1085/jgp.201812124
Published: 17 October 2018
View articletitled, A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine
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Journal Articles

Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites

Yali Wang, Elaine Yang, Marta M. Wells, Vasyl Bondarenko, Kellie Woll, Vincenzo Carnevale, Daniele Granata, Michael L. Klein, Roderic G. Eckenhoff, William P. Dailey, Manuel Covarrubias, Pei Tang, Yan Xu
Journal: Journal of General Physiology
J Gen Physiol (2018) 150 (9): 1317–1331.
https://doi.org/10.1085/jgp.201811993
Published: 17 July 2018
View articletitled, Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites
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Includes: Supplementary data
Journal Articles

Comparative sequence analysis suggests a conserved gating mechanism for TRP channels

Eugene Palovcak, Lucie Delemotte, Michael L. Klein, Vincenzo Carnevale
Journal: Journal of General Physiology
J Gen Physiol (2015) 146 (1): 37–50.
https://doi.org/10.1085/jgp.201411329
Published: 15 June 2015
View articletitled, Comparative sequence analysis suggests a conserved gating mechanism for TRP channels
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Includes: Supplementary data
Journal Articles

Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy

Adrien Moreau, Pascal Gosselin-Badaroudine, Lucie Delemotte, Michael L. Klein, Mohamed Chahine
Journal: Journal of General Physiology
J Gen Physiol (2015) 145 (2): 93–106.
https://doi.org/10.1085/jgp.201411304
Published: 26 January 2015
View articletitled, Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy
Open the PDF for Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy in another window
Includes: Supplementary data
Journal Articles

Evolutionary imprint of activation: The design principles of VSDs

Eugene Palovcak, Lucie Delemotte, Michael L. Klein, Vincenzo Carnevale
Journal: Journal of General Physiology
J Gen Physiol (2014) 143 (2): 145–156.
https://doi.org/10.1085/jgp.201311103
Published: 27 January 2014
View articletitled, Evolutionary imprint of activation: The design principles of VSDs
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Includes: Supplementary data
Journal Articles

An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations

Ernesto Vargas, Vladimir Yarov-Yarovoy, Fatemeh Khalili-Araghi, William A. Catterall, Michael L. Klein, Mounir Tarek, Erik Lindahl, Klaus Schulten, Eduardo Perozo, Francisco Bezanilla, Benoît Roux
Journal: Journal of General Physiology
J Gen Physiol (2012) 140 (6): 587–594.
https://doi.org/10.1085/jgp.201210873
Published: 26 November 2012
View articletitled, An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations
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Includes: Supplementary data