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Journal Articles

Mechanism of hydrophobic gating in the acetylcholine receptor channel pore

Monika Kumari, Nadira Khatoon, Rachita Sharma, Sushanth Adusumilli, Anthony Auerbach, Hemant K. Kashyap, Tapan K. Nayak

J Gen Physiol (2023) 156 (2): e202213189.

https://doi.org/10.1085/jgp.202213189

Published: 28 December 2023

View article titled, Mechanism of hydrophobic gating in the acetylcholine receptor channel pore

Includes: Supplementary data

Journal Articles

Pathways for nicotinic receptor desensitization

Anthony Auerbach

J Gen Physiol (2020) 152 (10): e202012639.

https://doi.org/10.1085/jgp.202012639

Published: 10 September 2020

View article titled, Pathways for nicotinic receptor desensitization

Journal Articles

Correction: Efficiency measures the conversion of agonist binding energy into receptor conformational change

Tapan K. Nayak, Ridhima Vij, Iva Bruhova, Jayasha Shandilya, Anthony Auerbach

J Gen Physiol (2019) 152 (1): e20181221511252019c.

https://doi.org/10.1085/jgp.20181221511252019c

Published: 05 December 2019

Journal Articles

A single molecular distance predicts agonist binding energy in nicotinic receptors

In Special Collection:

Ligand-gated ion channels

Sushree Tripathy, Wenjun Zheng, Anthony Auerbach

J Gen Physiol (2019) 151 (4): 452–464.

https://doi.org/10.1085/jgp.201812212

Published: 11 January 2019

View article titled, A single molecular distance predicts agonist binding energy in nicotinic receptors

Journal Articles

Efficiency measures the conversion of agonist binding energy into receptor conformational change

In Special Collection:

Excitatory Synapses

Tapan K. Nayak, Ridhima Vij, Iva Bruhova, Jayasha Shandilya, Anthony Auerbach

J Gen Physiol (2019) 151 (4): 465–477.

https://doi.org/10.1085/jgp.201812215

Published: 11 January 2019

View article titled, Efficiency measures the conversion of agonist binding energy into receptor conformational change

Journal Articles

A mechanism for acetylcholine receptor gating based on structure, coupling, phi, and flip

Shaweta Gupta, Srirupa Chakraborty, Ridhima Vij, Anthony Auerbach

J Gen Physiol (2016) 149 (1): 85–103.

https://doi.org/10.1085/jgp.201611673

Published: 08 December 2016

View article titled, A mechanism for acetylcholine receptor gating based on structure, coupling, phi, and flip

Includes: Supplementary data

Journal Articles

Modal affinities of endplate acetylcholine receptors caused by loop C mutations

Ridhima Vij, Prasad Purohit, Anthony Auerbach

J Gen Physiol (2015) 146 (5): 375–386.

https://doi.org/10.1085/jgp.201511503

Published: 26 October 2015

View article titled, Modal affinities of endplate acetylcholine receptors caused by loop C mutations

Journal Articles

Loop C and the mechanism of acetylcholine receptor–channel gating

Prasad Purohit, Anthony Auerbach

J Gen Physiol (2013) 141 (4): 467–478.

https://doi.org/10.1085/jgp.201210946

Published: 11 March 2013

View article titled, Loop C and the mechanism of acetylcholine receptor–channel gating

Journal Articles

Action of nicotine and analogs on acetylcholine receptors having mutations of transmitter-binding site residue αG153

Snehal Jadey, Prasad Purohit, Anthony Auerbach

J Gen Physiol (2012) 141 (1): 95–104.

https://doi.org/10.1085/jgp.201210896

Published: 31 December 2012

View article titled, Action of nicotine and analogs on acetylcholine receptors having mutations of transmitter-binding site residue αG153

Includes: Supplementary data

Journal Articles

An integrated catch-and-hold mechanism activates nicotinic acetylcholine receptors

Snehal Jadey, Anthony Auerbach

J Gen Physiol (2012) 140 (1): 17–28.

https://doi.org/10.1085/jgp.201210801

Published: 25 June 2012

View article titled, An integrated catch-and-hold mechanism activates nicotinic acetylcholine receptors

Journal Articles

The intrinsic energy of the gating isomerization of a neuromuscular acetylcholine receptor channel

Tapan K. Nayak, Prasad G. Purohit, Anthony Auerbach

J Gen Physiol (2012) 139 (5): 349–358.

https://doi.org/10.1085/jgp.201110752

Published: 30 April 2012

View article titled, The intrinsic energy of the gating isomerization of a neuromuscular acetylcholine receptor channel

Includes: Supplementary data

Journal Articles

Energetics of gating at the apo–acetylcholine receptor transmitter binding site

Prasad Purohit, Anthony Auerbach

J Gen Physiol (2010) 135 (4): 321–331.

https://doi.org/10.1085/jgp.200910384

Published: 29 March 2010

View article titled, Energetics of gating at the apo–acetylcholine receptor transmitter binding site

Includes: Supplementary data

Journal Articles

How to Turn the Reaction Coordinate into Time

Anthony Auerbach

J Gen Physiol (2007) 130 (6): 543–546.

https://doi.org/10.1085/jgp.200709898

Published: 26 November 2007

View article titled, How to Turn the Reaction Coordinate into Time

Journal Articles

Acetylcholine Receptor Gating: Movement in the α-Subunit Extracellular Domain

Prasad Purohit, Anthony Auerbach

J Gen Physiol (2007) 130 (6): 569–579.

https://doi.org/10.1085/jgp.200709858

Published: 26 November 2007

View article titled, Acetylcholine Receptor Gating: Movement in the α-Subunit Extracellular Domain

Journal Articles

Acetylcholine Receptor Gating at Extracellular Transmembrane Domain Interface: the “Pre-M1” Linker

Prasad Purohit, Anthony Auerbach

J Gen Physiol (2007) 130 (6): 559–568.

https://doi.org/10.1085/jgp.200709857

Published: 26 November 2007

View article titled, Acetylcholine Receptor Gating at Extracellular Transmembrane Domain Interface: the “Pre-M1” Linker

Journal Articles

Acetylcholine Receptor Gating at Extracellular Transmembrane Domain Interface: the Cys-Loop and M2–M3 Linker

Archana Jha, David J. Cadugan, Prasad Purohit, Anthony Auerbach

J Gen Physiol (2007) 130 (6): 547–558.

https://doi.org/10.1085/jgp.200709856

Published: 26 November 2007

View article titled, Acetylcholine Receptor Gating at Extracellular Transmembrane Domain Interface: the Cys-Loop and M2–M3 Linker

Journal Articles

Gating Dynamics of the Acetylcholine Receptor Extracellular Domain

Sudha Chakrapani, Timothy D. Bailey, Anthony Auerbach

J Gen Physiol (2004) 123 (4): 341–356.

https://doi.org/10.1085/jgp.200309004

Published: 29 March 2004

View article titled, Gating Dynamics of the Acetylcholine Receptor Extracellular Domain

Journal Articles

The Role of Loop 5 in Acetylcholine Receptor Channel Gating

Sudha Chakrapani, Timothy D. Bailey, Anthony Auerbach

J Gen Physiol (2003) 122 (5): 521–539.

https://doi.org/10.1085/jgp.200308885

Published: 13 October 2003

View article titled, The Role of Loop 5 in Acetylcholine Receptor Channel Gating

Journal Articles

Na⁺ Occupancy and Mg²⁺ Block of the N-Methyl-d-Aspartate Receptor Channel

Yongling Zhu, Anthony Auerbach

J Gen Physiol (2001) 117 (3): 275–286.

https://doi.org/10.1085/jgp.117.3.275

Published: 26 February 2001

View article titled, Na+ Occupancy and Mg2+ Block of the N-Methyl-d-Aspartate Receptor Channel

Journal Articles

K⁺ Occupancy of the N-Methyl-d-Aspartate Receptor Channel Probed by Mg²⁺ Block

Yongling Zhu, Anthony Auerbach

J Gen Physiol (2001) 117 (3): 287–298.

https://doi.org/10.1085/jgp.117.3.287

Published: 26 February 2001

View article titled, K+ Occupancy of the N-Methyl-d-Aspartate Receptor Channel Probed by Mg2+ Block

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Date

Mechanism of hydrophobic gating in the acetylcholine receptor channel pore

Pathways for nicotinic receptor desensitization

Correction: Efficiency measures the conversion of agonist binding energy into receptor conformational change

A single molecular distance predicts agonist binding energy in nicotinic receptors

Efficiency measures the conversion of agonist binding energy into receptor conformational change

A mechanism for acetylcholine receptor gating based on structure, coupling, phi, and flip

Modal affinities of endplate acetylcholine receptors caused by loop C mutations

Loop C and the mechanism of acetylcholine receptor–channel gating

Action of nicotine and analogs on acetylcholine receptors having mutations of transmitter-binding site residue αG153

An integrated catch-and-hold mechanism activates nicotinic acetylcholine receptors

The intrinsic energy of the gating isomerization of a neuromuscular acetylcholine receptor channel

Energetics of gating at the apo–acetylcholine receptor transmitter binding site

How to Turn the Reaction Coordinate into Time

Acetylcholine Receptor Gating: Movement in the α-Subunit Extracellular Domain

Acetylcholine Receptor Gating at Extracellular Transmembrane Domain Interface: the “Pre-M1” Linker

Acetylcholine Receptor Gating at Extracellular Transmembrane Domain Interface: the Cys-Loop and M2–M3 Linker

Gating Dynamics of the Acetylcholine Receptor Extracellular Domain

The Role of Loop 5 in Acetylcholine Receptor Channel Gating

Na⁺ Occupancy and Mg²⁺ Block of the N-Methyl-d-Aspartate Receptor Channel

K⁺ Occupancy of the N-Methyl-d-Aspartate Receptor Channel Probed by Mg²⁺ Block

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