We are pleased to present a collection of articles on excitatory synapses that have been curated from recent issues of JGP.
Excitatory synapses are the primary means by which information is communicated from one region of the central nervous system to another. Dynamic changes to their structure and molecular composition are associated with functional changes that underlie experience-dependent plasticity. Correspondingly, disruption of excitatory synaptic function is associated with psychiatric disease, neurodegeneration, epilepsy and addiction.
The articles in this collection provide fundamental mechanistic insight into the function and dysfunction of excitatory synapses. They cover research on the release and retrieval of synaptic vesicles; structure, function and pharmacology of glutamate receptors; and the cellular action of some common drugs. We hope you enjoy these articles, all of which are freely available for a limited period.
Image © 2019 Shi et al.