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Excitatory Synapses

A collection of fundamental mechanistic insight into the function and dysfunction of excitatory synapses. Research covers the release and retrieval of synaptic vesicles; structure, function and pharmacology of glutamate receptors; and the cellular action of some common drugs.

Excitatory synapses are the primary means by which information is communicated from one region of the central nervous system to another. Dynamic changes to their structure and molecular composition are associated with functional changes that underlie experience-dependent plasticity. Correspondingly, disruption of excitatory synaptic function is associated with psychiatric disease, neurodegeneration, epilepsy and addiction.

We hope you enjoy these articles, all of which are freely available for a limited period.

Image © 2019 Shi et al.

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Sidharth Tyagi; Tyler R. Bendrick; Dilyana Filipova; Symeon Papadopoulos; Roger A. Bannister
DOI: 10.1085/jgp.201812237
Ruchi Kapoor; Thasin A. Peyear; Roger E. Koeppe, II; Olaf S. Andersen
DOI: 10.1085/jgp.201812263
Amol V. Shivange; Philip M. Borden; Anand K. Muthusamy; Aaron L. Nichols; Kallol Bera; Huan Bao; Ishak Bishara; Janice Jeon; Matthew J. Mulcahy; Bruce Cohen; Saidhbhe L. O'Riordan; Charlene Kim; Dennis A. Dougherty; Edwin R. Chapman; Jonathan S. Marvin; Loren L. Looger; Henry A. Lester
DOI: 10.1085/jgp.201812201
Tapan K. Nayak; Ridhima Vij; Iva Bruhova; Jayasha Shandilya; Anthony Auerbach
DOI: 10.1085/jgp.201812215
Edward Y. Shi; Christine L. Yuan; Matthew T. Sipple; Jayasri Srinivasan; Christopher P. Ptak; Robert E. Oswald; Linda M. Nowak
DOI: 10.1085/jgp.201812209
Timothy J. Wilding; James E. Huettner
DOI: 10.1085/jgp.201812234
Kasper B. Hansen; Feng Yi; Riley E. Perszyk; Hiro Furukawa; Lonnie P. Wollmuth; Alasdair J. Gibb; Stephen F. Traynelis
DOI: 10.1085/jgp.201812032
Daniel D. MacDougall; Zesen Lin; Nara L. Chon; Skyler L. Jackman; Hai Lin; Jefferson D. Knight; Arun Anantharam
DOI: 10.1085/jgp.201711944
Xiangyi Wen; Matthew J. Van Hook; Justin J. Grassmeyer; Alex I. Wiesman; Grace M. Rich; Karlene M. Cork; Wallace B. Thoreson
DOI: 10.1085/jgp.201711919
Patricia M.G.E. Brown; Hugo McGuire; Derek Bowie
DOI: 10.1085/jgp.201711895
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