Issues

Localized calcium release from ryanodine-sensitive stores in large dense core vesicles may modulate secretion of neuropeptides from neurohypophysial terminals.

Extracellular anions more permeant than Cl⁻ modulate TMEM16B gating to promote channel opening, whereas less permeant anions favor channel closure.

Functional acid-sensing ion channels are present in olfactory bulb neurons and may contribute to normal olfaction.

After illumination, rod photoreceptors show a paradoxical increase in sensitivity to light.

VcINDY, a bacterial homolog of transporters implicated in lifespan in fruit flies and insulin resistance in mammals, is a high affinity, electrogenic, Na⁺-dependent dicarboxylate transporter.

The ATP activation signal in trimeric P2X₂ receptors propagates down individual subunits before spreading to all three at the level of the pore.

T-tubule uncoupling from the plasma membrane leads to myocardial contractile abnormalities.