1 January 2014
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Cover Image
Cover Image
Cover picture: Nicotine acts as a pharmacological chaperone for nAChRs in the early exocytic pathway, promoting their exit from the endoplasmic reticulum (ER) and eventually increasing their abundance at the plasma membrane. Nicotine-mediated up-regulation of nAChRs also depends on the COPI machinery involved in Golgi to ER transport of nAChRs (see research article by Henderson et al., 51–66, and associated animation at http://www.jgp.org/cgi/content/full/jgp.201311102/DC2).
[Image: Mary O’Reilly, O’Reilly Science Art] - PDF Icon PDF LinkTable of Contents
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ISSN 0022-1295
EISSN 1540-7748
Generally Physiological
Editorial
Perspective
Perspectives on: Cyclic nucleotide microdomains and signaling specificity
Architectural and functional roles of A kinase–anchoring proteins in cAMP microdomains
Perspectives on: Cyclic nucleotide microdomains and signaling specificity
Can we decipher the information content contained within cyclic nucleotide signals?
Perspectives on: Cyclic nucleotide microdomains and signaling specificity
Cyclic AMP compartments and signaling specificity: Role of cyclic nucleotide phosphodiesterases
Perspectives on: Cyclic nucleotide microdomains and signaling specificity
