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Issues

Generally Physiological

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A mitochondrial medley

Elizabeth M. Adler
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Editorial

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Articulating our values to clarify our mission: Inviting community participation

Sharona E. Gordon
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Perspective

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Perspectives on: Cyclic nucleotide microdomains and signaling specificity

Jeffrey W. Karpen
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Perspectives on: Cyclic nucleotide microdomains and signaling specificity

Architectural and functional roles of A kinase–anchoring proteins in cAMP microdomains

Michael S. Kapiloff,Marc Rigatti,Kimberly L. Dodge-Kafka
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Perspectives on: Cyclic nucleotide microdomains and signaling specificity

Can we decipher the information content contained within cyclic nucleotide signals?

Thomas C. Rich,Kristal J. Webb,Silas J. Leavesley
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Perspectives on: Cyclic nucleotide microdomains and signaling specificity

Cyclic AMP compartments and signaling specificity: Role of cyclic nucleotide phosphodiesterases

Marco Conti,Delphine Mika,Wito Richter
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Perspectives on: Cyclic nucleotide microdomains and signaling specificity

Mechanisms of cyclic AMP compartmentation revealed by computational models

Jeffrey J. Saucerman,Eric C. Greenwald,Renata Polanowska-Grabowska
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Commentary

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COPI polices nicotine-mediated up-regulation of nicotinic receptors

Rene Anand
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Article

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Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors

Brandon J. Henderson,Rahul Srinivasan,Weston A. Nichols,Crystal N. Dilworth,Diana F. Gutierrez,Elisha D.W. Mackey,Sheri McKinney,Ryan M. Drenan,Christopher I. Richards,Henry A. Lester
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Functional reconstitution of the mitochondrial Ca2+/H+ antiporter Letm1

Ming-Feng Tsai,Dawei Jiang,Linlin Zhao,David Clapham,Christopher Miller
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Divalent cations potentiate TRPV1 channel by lowering the heat activation threshold

Xu Cao,Linlin Ma,Fan Yang,KeWei Wang,Jie Zheng
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Divalent cations activate TRPV1 through promoting conformational change of the extracellular region

Fan Yang,Linlin Ma,Xu Cao,KeWei Wang,Jie Zheng
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Protonation controls ASIC1a activity via coordinated movements in multiple domains

Gaetano Bonifacio,Cláudia Igutti Suenaga Lelli,Stephan Kellenberger
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Communication

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Sarcolemmal ATP-sensitive potassium channels modulate skeletal muscle function under low-intensity workloads

Zhiyong Zhu,Ana Sierra,Colin M.-L. Burnett,Biyi Chen,Ekaterina Subbotina,Siva Rama Krishna Koganti,Zhan Gao,Yuejin Wu,Mark E. Anderson,Long-Sheng Song,David J. Goldhamer,William A. Coetzee,Denice M. Hodgson-Zingman,Leonid V. Zingman
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