A mechanism for different receptors coupled to the same G protein to generate different responses mediated by different second messengers

A schematic diagram of the IP₃ cytoplasmic Ca²⁺ branch of the PLC-mediated G_qPCR signaling pathway studied in Dickson et al. (2013) (modified from Fig. 5 A in Falkenburger et al., 2013). Elements highlighted in green were monitored in experiments described in Dickson et al. (2013), and those in gray are not directly described in Dickson et al. (2013).