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Journal Articles

Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammation

Jakob Loschko, Heidi A. Schreiber, Gereon J. Rieke, Daria Esterházy, Matthew M. Meredith, Virginia A. Pedicord, Kai-Hui Yao, Silvia Caballero, Eric G. Pamer, Daniel Mucida, Michel C. Nussenzweig

J Exp Med (2016) 213 (4): 517–534.

https://doi.org/10.1084/jem.20160062

Published: 21 March 2016

View article titled, Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammation

Includes: Supplementary data

Journal Articles

The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation

David Langlais, Luis B. Barreiro, Philippe Gros

J Exp Med (2016) 213 (4): 585–603.

https://doi.org/10.1084/jem.20151764

Published: 21 March 2016

View article titled, The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation

Includes: Supplementary data

Journal Articles

IL-12 drives functional plasticity of human group 2 innate lymphoid cells

Ai Ing Lim, Silvia Menegatti, Jacinta Bustamante, Lionel Le Bourhis, Matthieu Allez, Lars Rogge, Jean-Laurent Casanova, Hans Yssel, James P. Di Santo

J Exp Med (2016) 213 (4): 569–583.

https://doi.org/10.1084/jem.20151750

Published: 14 March 2016

View article titled, IL-12 drives functional plasticity of human group 2 innate lymphoid cells

Includes: Supplementary data

Journal Articles

Intestinal microbiota sustains inflammation and autoimmunity induced by hypomorphic RAG defects

J Exp Med (2016) 213 (3): 355–375.

https://doi.org/10.1084/jem.20151116

Published: 29 February 2016

View article titled, Intestinal microbiota sustains inflammation and autoimmunity induced by hypomorphic RAG defects

Includes: Supplementary data

Journal Articles

Antibodies against a secreted product of Staphylococcus aureus trigger phagocytic killing

Lena Thomer, Carla Emolo, Vilasack Thammavongsa, Hwan Keun Kim, Molly E. McAdow, Wenqi Yu, Matthew Kieffer, Olaf Schneewind, Dominique Missiakas

J Exp Med (2016) 213 (3): 293–301.

https://doi.org/10.1084/jem.20150074

Published: 15 February 2016

View article titled, Antibodies against a secreted product of Staphylococcus aureus trigger phagocytic killing

Includes: Supplementary data

Journal Articles

Type I IFN promotes NK cell expansion during viral infection by protecting NK cells against fratricide

Sharline Madera, Moritz Rapp, Matthew A. Firth, Joshua N. Beilke, Lewis L. Lanier, Joseph C. Sun

J Exp Med (2016) 213 (2): 225–233.

https://doi.org/10.1084/jem.20150712

Published: 11 January 2016

View article titled, Type I IFN promotes NK cell expansion during viral infection by protecting NK cells against fratricide

Journal Articles

Microbiota regulate the ability of lung dendritic cells to induce IgA class-switch recombination and generate protective gastrointestinal immune responses

Darren Ruane, Alejo Chorny, Haekyung Lee, Jeremiah Faith, Gaurav Pandey, Meimei Shan, Noa Simchoni, Adeeb Rahman, Aakash Garg, Erica G. Weinstein, Michael Oropallo, Michelle Gaylord, Ryan Ungaro, Charlotte Cunningham-Rundles, Konstantina Alexandropoulos, Daniel Mucida, Miriam Merad, Andrea Cerutti, Saurabh Mehandru

J Exp Med (2015) 213 (1): 53–73.

https://doi.org/10.1084/jem.20150567

Published: 28 December 2015

View article titled, Microbiota regulate the ability of lung dendritic cells to induce IgA class-switch recombination and generate protective gastrointestinal immune responses

Includes: Supplementary data

Journal Articles

Migratory CD103⁺ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12

Bart Everts, Roxane Tussiwand, Leentje Dreesen, Keke C. Fairfax, Stanley Ching-Cheng Huang, Amber M. Smith, Christina M. O’Neill, Wing Y. Lam, Brian T. Edelson, Joseph F. Urban, Jr., Kenneth M. Murphy, Edward J. Pearce

J Exp Med (2015) 213 (1): 35–51.

https://doi.org/10.1084/jem.20150235

Published: 28 December 2015

View article titled, Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12

Includes: Supplementary data

Journal Articles

XCR1⁺ dendritic cells promote memory CD8⁺ T cell recall upon secondary infections with Listeria monocytogenes or certain viruses

Yannick O. Alexandre, Sonia Ghilas, Cindy Sanchez, Agnès Le Bon, Karine Crozat, Marc Dalod

J Exp Med (2015) 213 (1): 75–92.

https://doi.org/10.1084/jem.20142350

Published: 22 December 2015

View article titled, XCR1+ dendritic cells promote memory CD8+ T cell recall upon secondary infections with Listeria monocytogenes or certain viruses

Includes: Supplementary data

Journal Articles

CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation

James M. Kennedy, Nassima Fodil, Sabrina Torre, Silayuv E. Bongfen, Jean-Frédéric Olivier, Vicki Leung, David Langlais, Charles Meunier, Joanne Berghout, Pinky Langat, Jeremy Schwartzentruber, Jacek Majewski, Mark Lathrop, Silvia M. Vidal, Philippe Gros

J Exp Med (2014) 211 (13): 2519–2535.

https://doi.org/10.1084/jem.20140455

Published: 17 November 2014

View article titled, CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation

Includes: Supplementary data

Journal Articles

Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants

J Exp Med (2014) 211 (12): 2361–2372.

https://doi.org/10.1084/jem.20141050

Published: 10 November 2014

View article titled, Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants

Journal Articles

Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell–dependent inflammation

Jian Wang, Fengqi Li, Haiming Wei, Zhe-Xiong Lian, Rui Sun, Zhigang Tian

J Exp Med (2014) 211 (12): 2397–2410.

https://doi.org/10.1084/jem.20140625

Published: 03 November 2014

View article titled, Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell–dependent inflammation

Includes: Supplementary data

Journal Articles

Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus

Syed Raza Ali, Jerry J. Fong, Aaron F. Carlin, Tamara D. Busch, Rebecka Linden, Takashi Angata, Thomas Areschoug, Mana Parast, Nissi Varki, Jeffrey Murray, Victor Nizet, Ajit Varki

J Exp Med (2014) 211 (6): 1231–1242.

https://doi.org/10.1084/jem.20131853

Published: 05 May 2014

View article titled, Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus

Includes: Supplementary data

Journal Articles

Interplay of host microbiota, genetic perturbations, and inflammation promotes local development of intestinal neoplasms in mice

Gerold Bongers, Michelle E. Pacer, Thais H. Geraldino, Lili Chen, Zhengxiang He, Daigo Hashimoto, Glaucia C. Furtado, Jordi Ochando, Kevin A. Kelley, Jose C. Clemente, Miriam Merad, Harm van Bakel, Sergio A. Lira

J Exp Med (2014) 211 (3): 457–472.

https://doi.org/10.1084/jem.20131587

Published: 03 March 2014

View article titled, Interplay of host microbiota, genetic perturbations, and inflammation promotes local development of intestinal neoplasms in mice

Includes: Supplementary data

Journal Articles

LECT2 protects mice against bacterial sepsis by activating macrophages via the CD209a receptor

Xin-Jiang Lu, Jiong Chen, Chao-Hui Yu, Yu-Hong Shi, Yu-Qing He, Rui-Cheng Zhang, Zuo-An Huang, Ji-Neng Lv, Shun Zhang, Lei Xu

J Exp Med (2012) 210 (1): 5–13.

https://doi.org/10.1084/jem.20121466

Published: 17 December 2012

View article titled, LECT2 protects mice against bacterial sepsis by activating macrophages via the CD209a receptor

Journal Articles

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

Matthieu Perreau, Anne-Laure Savoye, Elisa De Crignis, Jean-Marc Corpataux, Rafael Cubas, Elias K. Haddad, Laurence De Leval, Cecilia Graziosi, Giuseppe Pantaleo

J Exp Med (2012) 210 (1): 143–156.

https://doi.org/10.1084/jem.20121932

Published: 17 December 2012

View article titled, Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

Journal Articles

Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell–mediated deletion

Dimitra Peppa, Upkar S. Gill, Gary Reynolds, Nicholas J.W. Easom, Laura J. Pallett, Anna Schurich, Lorenzo Micco, Gaia Nebbia, Harsimran D. Singh, David H. Adams, Patrick T.F. Kennedy, Mala K. Maini

J Exp Med (2012) 210 (1): 99–114.

https://doi.org/10.1084/jem.20121172

Published: 17 December 2012

View article titled, Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell–mediated deletion

Includes: Supplementary data

Journal Articles

Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor

Bart Everts, Leonie Hussaarts, Nicole N. Driessen, Moniek H.J. Meevissen, Gabriele Schramm, Alwin J. van der Ham, Barbara van der Hoeven, Thomas Scholzen, Sven Burgdorf, Markus Mohrs, Edward J. Pearce, Cornelis H. Hokke, Helmut Haas, Hermelijn H. Smits, Maria Yazdanbakhsh

J Exp Med (2012) 209 (10): 1753–1767.

https://doi.org/10.1084/jem.20111381

Published: 10 September 2012

View article titled, Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor

Includes: Supplementary data

Journal Articles

Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening

Antonio DiGiandomenico, Paul Warrener, Melissa Hamilton, Sandrine Guillard, Peter Ravn, Ralph Minter, Maria Margarita Camara, Vignesh Venkatraman, Randall S. MacGill, Jia Lin, Qun Wang, Ashley Elaine Keller, Jessica C. Bonnell, Mladen Tomich, Lutz Jermutus, Michael P. McCarthy, David A. Melnick, JoAnn A. Suzich, C. Kendall Stover

J Exp Med (2012) 209 (7): 1273–1287.

https://doi.org/10.1084/jem.20120033

Published: 25 June 2012

View article titled, Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening

Journal Articles

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization

Laura E. McCoy, Anna Forsman Quigley, Nika M. Strokappe, Bianca Bulmer-Thomas, Michael S. Seaman, Daniella Mortier, Lucy Rutten, Nikita Chander, Carolyn J. Edwards, Robin Ketteler, David Davis, Theo Verrips, Robin A. Weiss

J Exp Med (2012) 209 (6): 1091–1103.

https://doi.org/10.1084/jem.20112655

Published: 28 May 2012

View article titled, Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization

Includes: Supplementary data

NARROW

Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammation

The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation

IL-12 drives functional plasticity of human group 2 innate lymphoid cells

Intestinal microbiota sustains inflammation and autoimmunity induced by hypomorphic RAG defects

Antibodies against a secreted product of Staphylococcus aureus trigger phagocytic killing

Type I IFN promotes NK cell expansion during viral infection by protecting NK cells against fratricide

Microbiota regulate the ability of lung dendritic cells to induce IgA class-switch recombination and generate protective gastrointestinal immune responses

Migratory CD103⁺ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12

XCR1⁺ dendritic cells promote memory CD8⁺ T cell recall upon secondary infections with Listeria monocytogenes or certain viruses

CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation

Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants

Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell–dependent inflammation

Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus

Interplay of host microbiota, genetic perturbations, and inflammation promotes local development of intestinal neoplasms in mice

LECT2 protects mice against bacterial sepsis by activating macrophages via the CD209a receptor

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell–mediated deletion

Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor

Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization

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