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PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice

In Special Collection:

2018 Nobel Prize Collection

Taku Okazaki, Il-mi Okazaki, Jian Wang, Daisuke Sugiura, Fumio Nakaki, Taku Yoshida, Yu Kato, Sidonia Fagarasan, Masamichi Muramatsu, Tomoo Eto, Kyoji Hioki, Tasuku Honjo

J Exp Med (2011) 208 (2): 395–407.

DOI: https://doi.org/10.1084/jem.20100466

Published: 07 February 2011

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Includes: Supplementary data

Journal Articles

AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements

Alexander L. Kovalchuk, Wendy duBois, Elizabeth Mushinski, Nicole E. McNeil, Carsten Hirt, Chen-Feng Qi, Zhaoyang Li, Siegfried Janz, Tasuku Honjo, Masamichi Muramatsu, Thomas Ried, Timothy Behrens, Michael Potter

J Exp Med (2007) 204 (12): 2989–3001.

DOI: https://doi.org/10.1084/jem.20070882

Published: 12 November 2007

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Includes: Supplementary data

Journal Articles

Unmutated Immunoglobulin M Can Protect Mice from Death by Influenza Virus Infection

Yuichi Harada, Masamichi Muramatsu, Toshikatsu Shibata, Tasuku Honjo, Kazumichi Kuroda

J Exp Med (2003) 197 (12): 1779–1785.

DOI: https://doi.org/10.1084/jem.20021457

Published: 09 June 2003

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Journal Articles

Constitutive Expression of AID Leads to Tumorigenesis

Il-mi Okazaki, Hiroshi Hiai, Naoki Kakazu, Shuichi Yamada, Masamichi Muramatsu, Kazuo Kinoshita, Tasuku Honjo

J Exp Med (2003) 197 (9): 1173–1181.

DOI: https://doi.org/10.1084/jem.20030275

Published: 05 May 2003

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Journal Articles

DNA Double-Strand Breaks : Prior to but not Sufficient in Targeting Hypermutation

Linda Bross, Masamichi Muramatsu, Kazuo Kinoshita, Tasuku Honjo, Heinz Jacobs

J Exp Med (2002) 195 (9): 1187–1192.

DOI: https://doi.org/10.1084/jem.20011749

Published: 06 May 2002

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Includes: Supplementary data

Journal Articles

Activation-induced Deaminase (AID)-directed Hypermutation in the Immunoglobulin Sμ Region : Implication of AID Involvement in a Common Step of Class Switch Recombination and Somatic Hypermutation

Hitoshi Nagaoka, Masamichi Muramatsu, Namiko Yamamura, Kazuo Kinoshita, Tasuku Honjo

J Exp Med (2002) 195 (4): 529–534.

DOI: https://doi.org/10.1084/jem.20012144

Published: 19 February 2002

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NARROW

PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice

AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements

Unmutated Immunoglobulin M Can Protect Mice from Death by Influenza Virus Infection

Constitutive Expression of AID Leads to Tumorigenesis

DNA Double-Strand Breaks : Prior to but not Sufficient in Targeting Hypermutation

Activation-induced Deaminase (AID)-directed Hypermutation in the Immunoglobulin Sμ Region : Implication of AID Involvement in a Common Step of Class Switch Recombination and Somatic Hypermutation

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PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice

AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements

Unmutated Immunoglobulin M Can Protect Mice from Death by Influenza Virus Infection

Constitutive Expression of AID Leads to Tumorigenesis

DNA Double-Strand Breaks : Prior to but not Sufficient in Targeting Hypermutation

Activation-induced Deaminase (AID)-directed Hypermutation in the Immunoglobulin Sμ Region : Implication of AID Involvement in a Common Step of Class Switch Recombination and Somatic Hypermutation

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