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Journal Articles

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice

Annie Mirsoian, Myriam N. Bouchlaka, Gail D. Sckisel, Mingyi Chen, Chien-Chun Steven Pai, Emanuel Maverakis, Richard G. Spencer, Kenneth W. Fishbein, Sana Siddiqui, Arta M. Monjazeb, Bronwen Martin, Stuart Maudsley, Charles Hesdorffer, Luigi Ferrucci, Dan L. Longo, Bruce R. Blazar, Robert H. Wiltrout, Dennis D. Taub, William J. Murphy
Journal: Journal of Experimental Medicine
J Exp Med (2014) 211 (12): 2373–2383.
https://doi.org/10.1084/jem.20140116
Published: 03 November 2014
View article titled, Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice
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Journal Articles

Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy

Myriam N. Bouchlaka, Gail D. Sckisel, Mingyi Chen, Annie Mirsoian, Anthony E. Zamora, Emanual Maverakis, Danice E.C. Wilkins, Kory L. Alderson, Hui-Hua Hsiao, Jonathan M. Weiss, Arta M. Monjazeb, Charles Hesdorffer, Luigi Ferrucci, Dan L. Longo, Bruce R. Blazar, Robert H. Wiltrout, Doug Redelman, Dennis D. Taub, William J. Murphy
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (11): 2223–2237.
https://doi.org/10.1084/jem.20131219
Published: 30 September 2013
View article titled, Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy
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Journal Articles

Bcl-2–Mediated Drug Resistance: Inhibition of Apoptosis by Blocking Nuclear Factor of Activated T Lymphocytes (Nfat)-Induced FAS Ligand Transcription

Rakesh K. Srivastava, Carl Y. Sasaki, J. Marie Hardwick, Dan L. Longo
Journal: Journal of Experimental Medicine
J Exp Med (1999) 190 (2): 253–266.
https://doi.org/10.1084/jem.190.2.253
Published: 19 July 1999
View article titled, Bcl-2–Mediated Drug Resistance: Inhibition of Apoptosis by Blocking Nuclear Factor of Activated T Lymphocytes (Nfat)-Induced FAS Ligand Transcription
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Journal Articles

Recombinant transforming growth factor beta 1 and beta 2 protect mice from acutely lethal doses of 5-fluorouracil and doxorubicin.

K Grzegorzewski, F W Ruscetti, N Usui, G Damia, D L Longo, J A Carlino, J R Keller, R H Wiltrout
Journal: Journal of Experimental Medicine
J Exp Med (1994) 180 (3): 1047–1057.
https://doi.org/10.1084/jem.180.3.1047
Published: 01 September 1994
View article titled, Recombinant transforming growth factor beta 1 and beta 2 protect mice from acutely lethal doses of 5-fluorouracil and doxorubicin.
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Journal Articles

Differential effects of growth hormone and prolactin on murine T cell development and function.

W J Murphy, S K Durum, D L Longo
Journal: Journal of Experimental Medicine
J Exp Med (1993) 178 (1): 231–236.
https://doi.org/10.1084/jem.178.1.231
Published: 01 July 1993
View article titled, Differential effects of growth hormone and prolactin on murine T cell development and function.
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Journal Articles

Selection of antigen-specific, idiotype-positive B cells in transgenic mice expressing a rearranged M167-mu heavy chain gene.

J J Kenny, C O'Connell, D G Sieckmann, R T Fischer, D L Longo
Journal: Journal of Experimental Medicine
J Exp Med (1991) 174 (5): 1189–1201.
https://doi.org/10.1084/jem.174.5.1189
Published: 01 November 1991
View article titled, Selection of antigen-specific, idiotype-positive B cells in transgenic mice expressing a rearranged M167-mu heavy chain gene.
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Journal Articles

Rearrangements and aberrant expression of the retinoic acid receptor alpha gene in acute promyelocytic leukemias.

L Longo, P P Pandolfi, A Biondi, A Rambaldi, A Mencarelli, F Lo Coco, D Diverio, L Pegoraro, G Avanzi, A Tabilio
Journal: Journal of Experimental Medicine
J Exp Med (1990) 172 (6): 1571–1575.
https://doi.org/10.1084/jem.172.6.1571
Published: 01 December 1990
View article titled, Rearrangements and aberrant expression of the retinoic acid receptor alpha gene in acute promyelocytic leukemias.
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Journal Articles

Expression and role of p75 interleukin 2 receptor on human monocytes.

I Espinoza-Delgado, J R Ortaldo, R Winkler-Pickett, K Sugamura, L Varesio, D L Longo
Journal: Journal of Experimental Medicine
J Exp Med (1990) 171 (5): 1821–1826.
https://doi.org/10.1084/jem.171.5.1821
Published: 01 May 1990
View article titled, Expression and role of p75 interleukin 2 receptor on human monocytes.
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Journal Articles

CD8 is required during positive selection of CD4-/CD8+ T cells.

J C Zúñiga-Pflücker, L A Jones, D L Longo, A M Kruisbeek
Journal: Journal of Experimental Medicine
J Exp Med (1990) 171 (2): 427–437.
https://doi.org/10.1084/jem.171.2.427
Published: 01 February 1990
View article titled, CD8 is required during positive selection of CD4-/CD8+ T cells.
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Journal Articles

Role of CD4 in thymocyte selection and maturation.

J C Zuñiga-Pflücker, S A McCarthy, M Weston, D L Longo, A Singer, A M Kruisbeek
Journal: Journal of Experimental Medicine
J Exp Med (1989) 169 (6): 2085–2096.
https://doi.org/10.1084/jem.169.6.2085
Published: 01 June 1989
View article titled, Role of CD4 in thymocyte selection and maturation.
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Journal Articles

Preferential differentiation of T cell receptor specificities based on the MHC glycoproteins encountered during development. Evidence for positive selection.

S Marusić-Galesić, D L Longo, A M Kruisbeek
Journal: Journal of Experimental Medicine
J Exp Med (1989) 169 (5): 1619–1630.
https://doi.org/10.1084/jem.169.5.1619
Published: 01 May 1989
View article titled, Preferential differentiation of T cell receptor specificities based on the MHC glycoproteins encountered during development. Evidence for positive selection.
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Journal Articles

Essential role of the interleukin 2-interleukin 2 receptor pathway in thymocyte maturation in vivo.

L Tentori, D L Longo, J C Zuñiga-Pflucker, C Wing, A M Kruisbeek
Journal: Journal of Experimental Medicine
J Exp Med (1988) 168 (5): 1741–1747.
https://doi.org/10.1084/jem.168.5.1741
Published: 01 November 1988
View article titled, Essential role of the interleukin 2-interleukin 2 receptor pathway in thymocyte maturation in vivo.
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Journal Articles

Human T cell leukemia/lymphoma virus I infection and subsequent cloning of normal human B cells. Direct responsiveness of cloned cells to recombinant interleukin 2 by differentiation in the absence of enhanced proliferation.

S Tomita, J L Ambrus, Jr, D J Volkman, D L Longo, H Mitsuya, M S Reitz, Jr, A S Fauci
Journal: Journal of Experimental Medicine
J Exp Med (1985) 162 (1): 393–398.
https://doi.org/10.1084/jem.162.1.393
Published: 01 July 1985
View article titled, Human T cell leukemia/lymphoma virus I infection and subsequent cloning of normal human B cells. Direct responsiveness of cloned cells to recombinant interleukin 2 by differentiation in the absence of enhanced proliferation.
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Journal Articles

Absence of the Lyt-2-,L3T4+ lineage of T cells in mice treated neonatally with anti-I-A correlates with absence of intrathymic I-A-bearing antigen-presenting cell function.

A M Kruisbeek, J J Mond, B J Fowlkes, J A Carmen, S Bridges, D L Longo
Journal: Journal of Experimental Medicine
J Exp Med (1985) 161 (5): 1029–1047.
https://doi.org/10.1084/jem.161.5.1029
Published: 01 May 1985
View article titled, Absence of the Lyt-2-,L3T4+ lineage of T cells in mice treated neonatally with anti-I-A correlates with absence of intrathymic I-A-bearing antigen-presenting cell function.
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Journal Articles

Interleukin 2 receptors on human B cells. Implications for the role of interleukin 2 in human B cell function.

A Muraguchi, J H Kehrl, D L Longo, D J Volkman, K A Smith, A S Fauci
Journal: Journal of Experimental Medicine
J Exp Med (1985) 161 (1): 181–197.
https://doi.org/10.1084/jem.161.1.181
Published: 01 January 1985
View article titled, Interleukin 2 receptors on human B cells. Implications for the role of interleukin 2 in human B cell function.
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Journal Articles

Self-recognition specificity expressed by T cells from nude mice. Absence of detectable Ia-restricted T cells in nude mice that do exhibit self-K/D-restricted T cell responses.

A M Kruisbeek, M L Davis, L A Matis, D L Longo
Journal: Journal of Experimental Medicine
J Exp Med (1984) 160 (3): 839–857.
https://doi.org/10.1084/jem.160.3.839
Published: 01 September 1984
View article titled, Self-recognition specificity expressed by T cells from nude mice. Absence of detectable Ia-restricted T cells in nude mice that do exhibit self-K/D-restricted T cell responses.
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Journal Articles

B lymphocyte immune response gene phenotype is genetically determined.

H Y Tse, J J Mond, D L Longo
Journal: Journal of Experimental Medicine
J Exp Med (1982) 155 (4): 1239–1244.
https://doi.org/10.1084/jem.155.4.1239
Published: 01 April 1982
View article titled, B lymphocyte immune response gene phenotype is genetically determined.
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Journal Articles

Gene complementation. Neither Ir-GLphi gene need be present in the proliferative T cell to generate an immune response to Poly(Glu55Lys36Phe9)n.

D L Longo, R H Schwartz
Journal: Journal of Experimental Medicine
J Exp Med (1980) 151 (6): 1452–1467.
https://doi.org/10.1084/jem.151.6.1452
Published: 01 June 1980
View article titled, Gene complementation. Neither Ir-GLphi gene need be present in the proliferative T cell to generate an immune response to Poly(Glu55Lys36Phe9)n.
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